NTRK3 antibody (AA 32-429)
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- Target See all NTRK3 Antibodies
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
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Binding Specificity
- AA 32-429
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This NTRK3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- purified
- Immunogen
- Purified recombinant extracellular fragment of human NTRK3 (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.
- Clone
- 4G5
- Isotype
- IgG1
- Top Product
- Discover our top product NTRK3 Primary Antibody
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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Gene expression of TrkC (NTRK3) in human soft tissue tumours." in: The Journal of pathology, Vol. 197, Issue 5, pp. 661-7, (2002) (PubMed).
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Gene expression of TrkC (NTRK3) in human soft tissue tumours." in: The Journal of pathology, Vol. 197, Issue 5, pp. 661-7, (2002) (PubMed).
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- Target
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
- Alternative Name
- NTRK3 (NTRK3 Products)
- Synonyms
- TRKC antibody, gp145(trkC) antibody, trkC antibody, AW125844 antibody, Ntrk3_tv3 antibody, TrkC antibody, neurotrophic receptor tyrosine kinase 3 antibody, neurotrophic tyrosine kinase, receptor, type 3 antibody, NTRK3 antibody, Ntrk3 antibody
- Background
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Description: NTRK3 (neurotrophic tyrosine kinase, receptor, type 3), it is a member of the neurotrophic tyrosine receptor kinase (NTRK) family and plays an important role in the development and maintenance of neural tissues. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Aliases: TRKC, gp145(trkC)
- Molecular Weight
- 94 kDa
- Gene ID
- 4916
- HGNC
- 4916
- Pathways
- RTK Signaling, Neurotrophin Signaling Pathway, Regulation of Cell Size
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