Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 637-651) antibody

Details for Product No. ABIN969538
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms MELK, xmelk, Melk, HPK38, AI327312, MPK38, mKIAA0175, fb71b01, fe01f04, wu:fb71b01, wu:fe01f04
Epitope
AA 637-651
(41), (15), (12), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(109), (21), (16), (6), (6), (2), (2), (2), (2)
Host
Mouse
(81), (22), (7)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(6), (6), (5), (5), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC)
(89), (52), (10), (7), (6), (6), (5), (4), (4), (2), (2)
Pubmed 2 references available
Quantity 0.1 mg
Options
Shipping to United States ( )
Availability Will be delivered in 3 to 4 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Immunogen Synthesized peptide of human MELK (AA 637-651: C-VYKRLVEDILSSCKV) .
Sequence VYKRLVEDIL SSCKV
Clone 2G2
Isotype IgG2a
Purification Purified
Alternative Name MELK (MELK Antibody Abstract)
Background Maternal embryonic leucine-zipper kinase (MELK) is a key regulator of survival of stemlike GBM cells in vitro. MELK expression is increased in breast cancer tissue and this increase is also associated with poor patient survival, as predicted for a candidate oncogene.
Molecular Weight 74.6 kDa
Gene ID 9833
HGNC 9833
Research Area Embryogenesis, Embryonic stem cells, Hormones, Receptors
Application Notes Recommended Dilution:
ELISA: 1/10000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide and 0.5 % protein stabilizer
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 637-651) antibody Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: ...
anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 637-651) antibody (2) Figure 4: Flow cytometric analysis of MCF-7 cells using MELK mouse mAb (green) and ne...
anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 637-651) antibody (3) Figure 3: Immunofluorescence analysis of HepG2 cells using MELK mouse mAb (green) . B...
anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 637-651) antibody (4) Figure 1: Immunohistochemical analysis of paraffin-embedded liver cancer tissues usin...
anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 637-651) antibody (5) Figure 2: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues usi...
Product cited in: Nakano, Joshi, Visnyei et al.: "Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway." in: Neuro-oncology, Vol. 13, Issue 6, pp. 622-34, 2011 (PubMed).

Pickard, Green, Ellis et al.: "Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer." in: Breast cancer research : BCR, Vol. 11, Issue 4, pp. R60, 2009 (PubMed).

Validation Images
Catalog No. ABIN969538
430.10 $
Plus shipping costs $45.00
Quantity
Price
0.1 mg
430.10 $

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)
Did you look for something else?