PTPN3 antibody (N-Term)
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- Target See all PTPN3 Antibodies
- PTPN3 (Protein tyrosine Phosphatase, Non-Receptor Type 3 (PTPN3))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PTPN3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ASAGVAVYRK YICTSFYPWV NILKISFKRK KFFIHQRQKQ AESREHIVAF
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against PTPN3. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product PTPN3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 782 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PTPN3 (Protein tyrosine Phosphatase, Non-Receptor Type 3 (PTPN3))
- Alternative Name
- PTPN3 (PTPN3 Products)
- Synonyms
- PTP-H1 antibody, PTPH1 antibody, 9530011I20Rik antibody, PTPCL antibody, protein tyrosine phosphatase, non-receptor type 3 antibody, PTPN3 antibody, Ptpn3 antibody
- Background
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DKFZp686N0569, PTPH1, PTP-H1
Protein Interaction Partner: NXT2, ZCCHC10, DIP2A, WDR6, LMO1, AKR1C1, YWHAQ, UBE3A, VDR, GHR, YWHAG, ADAM17, YWHAB, VCP, CD247, ZAP70, SFN,
Protein Size: 782 - Molecular Weight
- 86 kDa
- Gene ID
- 5774
- NCBI Accession
- NM_001145369, NP_001138841
- UniProt
- E9PGU7
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