You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Mouse (Murine) CAPNL1 antibody for Immunohistochemistry

Recommended CAPNL1 Antibody (supplied by: Log in to see )

Antigen
Calpain 1, Large Subunit (CAPNL1) Antibodies
  • CANP
  • CANP1
  • CANPL1
  • Capa-1
  • Capa1
  • mu-calpin
  • muCANP
  • muCL
  • si:ch211-203k12.4
  • si:dkeyp-101g1.3
Reactivity
Mouse (Murine), Rat (Rattus), Human
46
15
14
1
1
Host
Rabbit
30
18
4
Clonality
Polyclonal
Conjugate
This CAPNL1 antibody is un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
46
30
7
5
5
4
4
2
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN3021623
$ 302.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.22865479 ABIN2427867 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.22865479 ABIN2404014 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011340706 ABIN1871429 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011340706 ABIN2409242 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.0011340706 ABIN2989382 IHC WB Rabbit IgG Log in to see Polyclonal

Similar anti-CAPNL1 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 45 Antibodies 14 Antibodies 13 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 3 Antibodies 3 Antibodies 3 Antibodies
Immunohistochemistry (IHC) 6 Antibodies 6 Antibodies 8 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies 2 Antibodies 2 Antibodies
Immunofluorescence (IF) 5 Antibodies 1 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 2 Antibodies 2 Antibodies 2 Antibodies

General

Antigen Calpain 1, Large Subunit (CAPNL1) Antibodies
Reactivity Mouse (Murine), Rat (Rattus), Human
(46), (15), (14), (1), (1)
Host Rabbit
(30), (18), (4)
Clonality
Polyclonal
Conjugate This CAPNL1 antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(46), (30), (7), (5), (5), (4), (4), (2), (1)
Supplier Log in to see

Product Details anti-CAPNL1 Antibody

Target Details CAPNL1 Application Details Handling Images
Purification Affinity purification
Immunogen Recombinant protein of human CAPN1
Isotype IgG

Target Details CAPNL1

Product Details anti-CAPNL1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CAPN1 (CAPNL1 Antibody Abstract)
Background Calpain is a calcium-dependent thiol proteinase that is functionally active as a heterodimer composed of a small regulatory subunit and one of at least two large catalytic subunits (calpain 1 or calpain 2). In vitro, calpain 1 (mu-calpain) requires micromolar levels of calcium, while calpain 2 (M-calpain) requires millimolar levels of calcium for activation. The regulation of calpain in vivo is the subject of many current studies, which suggest that proteolytic activity is regulated post-transcriptionally by mechanisms such as calcium requirements, subcellular localization of the heterodimer, phosphorylation via the EGFR-Erk signaling cascade, endogenous inhibitors (calpastatin) and autoproteolytic cleavage. Calpastatin negatively regulates autoproteolytic cleavage of calpain 1 between Gly27 and Leu28. Calpain influences cell migration by modifying rather than degrading its substrates responsible for cell adhesion and cytoskeletal arrangement. Control of calpain activity has caught the attention of drug development since limiting its activity could mute invasiveness of tumors or chronic inflammation.
Synonyms: CAPN1, CANP, CANP1, CANPL1, muCANP, muCL
Gene ID 823
UniProt P07384
Pathways Apoptosis

Application Details

Product Details anti-CAPNL1 Antibody Target Details CAPNL1 Handling Images back to top
Application Notes Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
Restrictions For Research Use only

Handling

Product Details anti-CAPNL1 Antibody Target Details CAPNL1 Application Details Images back to top
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze / thaw cycles
Storage -20 °C/-80 °C

Images

Product Details anti-CAPNL1 Antibody Target Details CAPNL1 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-CAPNL1 antibody (Calpain 1, Large Subunit) (ABIN3021623) Western blot analysis of extracts of various cell lines, using CAPN1 antibody.
Immunohistochemistry (IHC) image for anti-CAPNL1 antibody (Calpain 1, Large Subunit) (ABIN3021623) anti-Calpain 1, Large Subunit (CAPNL1) antibody (Image 2)