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anti-Mouse (Murine) Caspase 1 antibody for Flow Cytometry

Recommended Caspase 1 Antibody (supplied by: Log in to see )

Antigen
Caspase 1 (CASP1) Antibodies
  • CASP1
  • ccp1
  • CG5370
  • dcp-1
  • DCP-1
  • dcp1
  • DCP1
  • Dcp1
  • Dmel\\CG5370
  • ICE
  • Ice
  • Il1bc
  • IL1BC
  • l(2)01862
  • l(2)02132
  • P45
Reactivity
Mouse (Murine)
246
72
51
8
2
2
1
1
1
1
1
1
Host
Rat
232
36
9
2
Clonality
Monoclonal
Conjugate
This Caspase 1 antibody is un-conjugated
19
14
8
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
226
127
119
75
24
19
16
6
5
5
3
2
2
Supplier
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Catalog No. ABIN2664090
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010485112 ABIN200371 FACS ELISA WB Rat IgG1 AA 206-220 Log in to see
0.0010485112 ABIN2664091 FACS Rat IgG2a Log in to see 5B10 3
0.0010485112 ABIN2218939 FACS ELISA WB Rat IgG1 AA 206-220 Log in to see 6D214
0.0010485112 ABIN2218938 FACS ELISA WB Rat IgG1 AA 206-220 Log in to see 6D213
0.0010485112 ABIN187450 EIA FACS WB Rat IgG1 Log in to see 1H11

Top referenced anti-Caspase 1 antibody for Flow Cytometry

Similar anti-Caspase 1 Antibodies

Application / Reactivity Mouse (Murine)
ELISA 18 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 6 Antibodies
Immunocytochemistry (ICC) 4 Antibodies
Immunofluorescence (IF) 8 Antibodies
Immunohistochemistry (IHC) 39 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 29 Antibodies
Immunoprecipitation (IP) 11 Antibodies
Western Blotting (WB) 65 Antibodies

General

Antigen Caspase 1 (CASP1) Antibodies
Reactivity Mouse (Murine)
(246), (72), (51), (8), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rat
(232), (36), (9), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Caspase 1 antibody is un-conjugated
(19), (14), (8), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS)
(226), (127), (119), (75), (24), (19), (16), (6), (5), (5), (3), (2), (2)
Pubmed 3 references available
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Product Details anti-Caspase 1 Antibody

Target Details Caspase 1 Application Details Handling References for anti-Caspase 1 Antibody (ABIN2664090) Images
Purification The antibody was purified by affinity chromatography.
Clone 5B10
Isotype IgG2a

Target Details Caspase 1

Product Details anti-Caspase 1 Antibody Application Details Handling References for anti-Caspase 1 Antibody (ABIN2664090) Images back to top
Antigen
Alternative Name Caspase-1 (CASP1 Antibody Abstract)
Background Caspase -1 plays a vital role in cleaving the inactive procytokine pro-IL-1 beta to generate the active 17 kd mature form of IL-1beta, a key mediator of inflammation. Active caspase-1 (ICE) is derived a single proenzyme of 45 Kd. An active ICE comprises two subunits of P20 and two subunits of P10 after removal a large amino-terminal pro-domain and a small linker peptide. Caspase-1 is reported to be involved in CD95- mediated apoptosis. Four alternatively spliced variants of caspase-1 have been reported, with mw ranging from 30-48 kd.
Research Area Apoptosis/Necrosis
Pathways Apoptosis

Application Details

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Handling References for anti-Caspase 1 Antibody (ABIN2664090) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details References for anti-Caspase 1 Antibody (ABIN2664090) Images back to top
Concentration 0.5 mg/mL
Buffer phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-Caspase 1 Antibody (ABIN2664090)

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details Handling Images back to top
Background publications

Kang, Wang, Kuida, Yuan: "Distinct downstream pathways of caspase-11 in regulating apoptosis and cytokine maturation during septic shock response." in: Cell death and differentiation, Vol. 9, Issue 10, pp. 1115-25, 2002

Kang, Wang, Hara, Peterson, Namura, Amin-Hanjani, Huang, Srinivasan, Tomaselli, Thornberry, Moskowitz, Yuan: "Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions." in: The Journal of cell biology, Vol. 149, Issue 3, pp. 613-22, 2000

Cohen: "Caspases: the executioners of apoptosis." in: The Biochemical journal, Vol. 326 ( Pt 1), Issue 5693, pp. 1-16, 1997

Images

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Supplier Images
Western Blotting (WB) image for anti-Caspase 1 antibody (CASP1) (ABIN2664090) anti-Caspase 1 (CASP1) antibody