anti-Human Caspase 10 antibody for Enzyme Immunoassay

Recommended Caspase 10 Antibody (supplied by: Log in to see )

Antigen
Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) Antibodies
  • xCaspase-10
  • alps2
  • caspace-10
  • caspase-10
  • flice2
  • mch4
  • xCaspace-10
  • ALPS2
  • FLICE2
  • MCH4
  • caspase 10, apoptosis-related cysteine peptidase
  • caspase-10
  • casp10
  • CASP10
  • Casp10
  • LOC100101580
Epitope
C-Term
26
8
6
6
5
5
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
151
32
28
2
1
1
Host
Rabbit
135
10
3
2
1
Clonality
Polyclonal
Conjugate
This Caspase 10 antibody is un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
125
44
37
31
22
14
13
7
7
3
2
1
1
1
Supplier
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Catalog No. ABIN5554652
$ 375.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1449660 EIA IF IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal

Similar anti-Caspase 10 Antibodies

Application / Reactivity Human
ELISA 44 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 8 Antibodies
Immunofluorescence (IF) 23 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 7 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 38 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 32 Antibodies
Immunoprecipitation (IP) 14 Antibodies
Intracellular Flow Cytometry (ICFC) 1 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Western Blotting (WB) 127 Antibodies

General

Antigen Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) Antibodies
Epitope C-Term
(26), (8), (6), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(151), (32), (28), (2), (1), (1)
Host Rabbit
(135), (10), (3), (2), (1)
Clonality
Polyclonal
Conjugate This Caspase 10 antibody is un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(125), (44), (37), (31), (22), (14), (13), (7), (7), (3), (2), (1), (1), (1)
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Product Details anti-Caspase 10 Antibody

Target Details Caspase 10 Application Details Handling Images
Specificity Caspase-10 antibody was raised against a peptide corresponding to amino acids 505 to 521 of human FLICE2. Antibody only recognizes FLICE2 form of caspase-10.
Purification DEAE
Immunogen Human Caspase-10 (C-Terminus) Peptide
Isotype IgG

Target Details Caspase 10

Product Details anti-Caspase 10 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Caspase-10 (CASP10 Antibody Abstract)
Background Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. A novel ICE/CED-3 protease was identified recently, designated FLICE2 and Mch41,2 and renamed as caspase-10. Caspase-10 has two death effector domains (DEDs) that bind to the DED in the adapter molecule FADD and recruits both TNFR1 and CD95 to form complexes with these receptors. Caspase-10 is therefore involved in the CD95 and TNFR1 induced apoptosis1. Caspase-10 cleaves and activates caspase-3, -4, -6, -7, -8 and -9, which causes the proteolytic cleavage of many key proteins such as PARP. Cleavage of PARP occurs in many different systems during apoptosis and is the hallmark of programmed cell death. Caspase-10 is expressed in many tissues and cell lines.Synonyms: Apoptotic protease Mch-4, CASP-10, CASP10, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE-like apoptotic protease 4, MCH4
Gene ID 843
UniProt Q92851
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-Caspase 10 Antibody Target Details Caspase 10 Handling Images back to top
Application Notes ELISA. Western Blot: Caspase-10 antibody can be used for detection of caspase-10 at 1/500 to1/1000 dilution. A 59 kDa band can be detected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 10 Antibody Target Details Caspase 10 Application Details Images back to top
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.