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anti-Rat (Rattus) Caspase 2 antibody for Immunohistochemistry

Recommended Caspase 2 Antibody (supplied by: Log in to see )

Antigen
Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) Antibodies
  • CASP-2
  • Caspase-2
  • ICH-1
  • ICH-1L/1S
  • ICH1
  • ICH1L1S
  • NEDD-2
  • Nedd2
  • NEDD2
  • PPP1R57
  • xCaspase-2
Reactivity
Human, Mouse (Murine), Rat (Rattus)
202
63
45
6
2
2
Host
Rabbit
159
53
11
Clonality
Polyclonal
Conjugate
This Caspase 2 antibody is un-conjugated
6
6
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
178
102
40
30
13
12
11
10
9
7
4
4
1
1
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Catalog No. ABIN222882
$ 283.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0011325823 ABIN2406520 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011325823 ABIN2427573 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.0011325823 ABIN2561574 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011325823 ABIN2976269 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011325823 ABIN1885021 IHC ELISA WB Rabbit Log in to see Polyclonal

Top referenced anti-Caspase 2 antibody for Immunohistochemistry

Similar anti-Caspase 2 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Human
Western Blotting (WB) 32 Antibodies 48 Antibodies 162 Antibodies
Immunoprecipitation (IP) 10 Antibodies 4 Antibodies 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 27 Antibodies 12 Antibodies 6 Antibodies
Immunohistochemistry (IHC) 41 Antibodies 6 Antibodies 6 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 6 Antibodies 3 Antibodies 2 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies

General

Antigen Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(202), (63), (45), (6), (2), (2)
Host Rabbit
(159), (53), (11)
Clonality
Polyclonal
Conjugate This Caspase 2 antibody is un-conjugated
(6), (6), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(178), (102), (40), (30), (13), (12), (11), (10), (9), (7), (4), (4), (1), (1)
Pubmed 2 references available
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Product Details anti-Caspase 2 Antibody

Target Details Caspase 2 Application Details Handling References for anti-Caspase 2 Antibody (ABIN222882) Images
Blocking Peptide Blocking peptide for this product available: ABIN412649
Specificity Detects the full length and small subunit of caspase-2.
Purification Affinity purified
Immunogen Synthetic peptide surrounding amino acid 417 of mouse caspase-2
Isotype IgG

Target Details Caspase 2

Product Details anti-Caspase 2 Antibody Application Details Handling References for anti-Caspase 2 Antibody (ABIN222882) Images back to top
Antigen
Alternative Name Caspase-2 (CASP2 Antibody Abstract)
Background Caspases play a key role in apoptosis. Similar as other caspases, caspase-2 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Caspase-2 mRNA is alternatively spliced. The larger mRNA species encoding a product of 435 amino acids is known as ICH-1L. The smaller mRNA species encoding a protein of 312 amino acids is named ICH-1S. Over expression of ICH-1L induces apoptosis, while over expression of ICH-1S suppresses Rat-1 cell death induced by serum deprivation.
Synonyms: CASP-2, NEDD-2,NEDD2, ICH1, ICH-1L/1S, ICH-1L, EC 3.4.22.55
Gene ID 12366
Research Area Apoptosis/Necrosis, Cancer, Autophagy
Pathways Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway

Application Details

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Handling References for anti-Caspase 2 Antibody (ABIN222882) Images back to top
Application Notes Western blotting (1-2 μg/mL), and Immunohistochemistry (5 μg/mL).
However, the optimal conditions should be determined individually.
Comment

Suggested positive control: Western Blot: Jurkat cell lysate, treated and untreated. IHC: Placenta tissue.
Country of Animal Origin: China

Restrictions For Research Use only

Handling

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Application Details References for anti-Caspase 2 Antibody (ABIN222882) Images back to top
Format Liquid
Concentration 0.2 mg/mL
Buffer 100 μg (0.2 mg/mL) affinity purified rabbit anti-caspase-2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months

References for anti-Caspase 2 Antibody (ABIN222882)

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Application Details Handling Images back to top
Product cited in:

Zhu, Sun, Okano, Chen, Zhang, Maeda, Palczewski: "Sponge transgenic mouse model reveals important roles for the microRNA-183 (miR-183)/96/182 cluster in postmitotic photoreceptors of the retina." in: The Journal of biological chemistry, Vol. 286, Issue 36, pp. 31749-60, 2011

Basu, Adkins, Basu: "Down-regulation of caspase-2 by rottlerin via protein kinase C-delta-independent pathway." in: Cancer research, Vol. 68, Issue 8, pp. 2795-802, 2008

Images

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Application Details Handling References for anti-Caspase 2 Antibody (ABIN222882) back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 2 antibody (Caspase 2, Apoptosis-Related Cysteine Peptidase) (ABIN222882) Western blot analysis of caspase-2 in untreated (Lane and treated (Lane cell lysate.