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anti-Human Caspase 8 antibody for Enzyme Immunoassay

Recommended Caspase 8 Antibody (supplied by: Log in to see )

Antigen
Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
  • ALPS2B
  • CAP4
  • Casp-8
  • CASP-8
  • casp8
  • CASP8
  • casp8-A
  • caspase-8
  • FLICE
  • MACH
  • Mch5
  • MCH5
  • xCaspase-8
  • zgc:92075
Epitope
C-Term
47
18
17
17
13
10
10
8
8
7
7
6
6
5
5
5
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
339
96
69
18
18
14
4
1
1
1
Host
Rabbit
271
101
11
2
Clonality
Polyclonal
Conjugate
This Caspase 8 antibody is un-conjugated
17
12
8
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
323
113
81
70
42
34
31
24
12
11
7
5
2
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN452817
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008870071 ABIN499573 EIA IF WB Rabbit IgG C-Term Log in to see Polyclonal 4
0.0008870071 ABIN499575 EIA WB Rabbit IgG Log in to see Polyclonal 4
0.0008870071 ABIN1105678 EIA FACS IHC (p) WB Mouse IgG1 Log in to see 1H11
0.0008870071 ABIN187520 EIA Mouse IgG1 N-Term Log in to see FLICE-3
0.0008870071 ABIN1105680 EIA WB Mouse IgG Log in to see 04-01-20
0.0008870071 ABIN2717103 EIA Rabbit IgG Log in to see Polyclonal

Top referenced anti-Caspase 8 antibody for Enzyme Immunoassay

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Application / Reactivity Human
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ELISA 90 Antibodies
Enzyme Immunoassay (EIA) 7 Antibodies
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Immunoassay (IA) 1 Antibodies
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Immunocytochemistry (ICC) 22 Antibodies
Immunofluorescence (IF) 23 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 77 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 68 Antibodies
Immunoprecipitation (IP) 44 Antibodies
Immunostaining (ISt) 1 Antibodies

General

Antigen Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
Epitope C-Term
(47), (18), (17), (17), (13), (10), (10), (8), (8), (7), (7), (6), (6), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(339), (96), (69), (18), (18), (14), (4), (1), (1), (1)
Host Rabbit
(271), (101), (11), (2)
Clonality
Polyclonal
Conjugate This Caspase 8 antibody is un-conjugated
(17), (12), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(323), (113), (81), (70), (42), (34), (31), (24), (12), (11), (7), (5), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-Caspase 8 Antibody

Target Details Caspase 8 Application Details Handling References for anti-Caspase 8 Antibody (ABIN452817) Images
Specificity This antibody detects
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen KLH conjugated synthetic peptide selected from the C-terminal region of human CASP8

Target Details Caspase 8

Product Details anti-Caspase 8 Antibody Application Details Handling References for anti-Caspase 8 Antibody (ABIN452817) Images back to top
Antigen
Alternative Name Caspase-8 (CASP8 Antibody Abstract)
Background CASP8 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases.Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, CASP-8, CASP8, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, ICE-like apoptotic protease 5, MCH5, MORT1-associated CED-3 homolog
Molecular Weight 55391 Da
Gene ID 841
NCBI Accession NP_001073593
UniProt Q14790
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling

Application Details

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Handling References for anti-Caspase 8 Antibody (ABIN452817) Images back to top
Application Notes Western blot: 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details References for anti-Caspase 8 Antibody (ABIN452817) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

References for anti-Caspase 8 Antibody (ABIN452817)

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling Images back to top
Background publications

Ji, Gu, Hu, Wang, Liang, Xia, Lu, Song, Fu, Wang: "Polymorphisms in cell death pathway genes are associated with altered sperm apoptosis and poor semen quality." in: Human reproduction (Oxford, England), Vol. 24, Issue 10, pp. 2439-46, 2009

Images

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling References for anti-Caspase 8 Antibody (ABIN452817) back to top
Supplier Images
 image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (C-Term) (ABIN452817) anti-Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) (C-Term) antibody