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anti-Human Caspase 8 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Caspase 8 Antibody (supplied by: Log in to see )

Antigen
Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
  • ALPS2B
  • CAP4
  • Casp-8
  • CASP-8
  • casp8
  • CASP8
  • casp8-A
  • caspase-8
  • FLICE
  • MACH
  • Mch5
  • MCH5
  • xCaspase-8
  • zgc:92075
Epitope
C-Term
47
18
18
17
13
10
10
8
8
7
7
6
6
5
5
5
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
342
96
69
19
18
14
4
1
1
1
Host
Rabbit
271
104
11
2
Clonality
Polyclonal
Conjugate
This Caspase 8 antibody is un-conjugated
18
12
8
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
326
114
81
69
42
34
31
23
12
11
8
5
2
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN615326
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.34288716 ABIN615327 IHC (p) WB Rabbit C-Term, Isoform E Log in to see Polyclonal
0.34288716 ABIN307184 IHC (p) IP WB Rabbit IgG Log in to see Polyclonal
0.0008982679 ABIN724205 IF (p) IHC (p) WB Rabbit IgG AA 430-482 Log in to see Polyclonal 4
0.0008982679 ABIN390474 FACS IF IHC (p) WB Rabbit Ig AA 432-461, C-Term Log in to see Polyclonal 2
0.0008982679 ABIN271875 IHC (p) WB Rabbit Log in to see Polyclonal
0.0008982679 ABIN127031 IHC (p) WB Rabbit Cleavage Site, active Log in to see Polyclonal
0.0008982679 ABIN1688339 IHC (p) Rabbit IgG N-Term Log in to see Polyclonal
0.0008982679 ABIN1687079 IHC (p) Rabbit IgG N-Term Log in to see Polyclonal
0.0008982679 ABIN189211 FACS IHC (p) IP IHC WB Rabbit IgG N-Term Log in to see E6
0.0008982679 ABIN372513 IHC (p) IP WB Rabbit IgG Log in to see Polyclonal
0.0008982679 ABIN373123 IHC (p) Rabbit N-Term Log in to see Polyclonal
0.0008982679 ABIN269525 IHC (p) IP IHC WB Mouse IgG1 kappa Log in to see 8CSP03
0.0008982679 ABIN3044129 IHC (p) WB Rabbit IgG AA 257-277, N-Term Log in to see Polyclonal
0.0008982679 ABIN3044432 IHC (p) WB Rabbit IgG AA 458-473, C-Term Log in to see Polyclonal
0.0008982679 ABIN957192 IHC (fro) IHC (p) IP WB Rabbit Log in to see Polyclonal
0.0008982679 ABIN462480 ICC IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.0008982679 ABIN2854891 ICC IF IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
0.0008982679 ABIN957191 IHC (fro) IHC (p) IP WB Rabbit Log in to see Polyclonal
0.0008982679 ABIN462481 IHC (p) WB Rabbit Log in to see Polyclonal
0.0008982679 ABIN2618013 IHC (p) WB Rabbit IgG AA 458-473 Log in to see Polyclonal

Top referenced anti-Caspase 8 antibody for Immunohistochemistry (Paraffin-embedded Sections)

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Application / Reactivity Human
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Enzyme Immunoassay (EIA) 7 Antibodies
Flow Cytometry (FACS) 31 Antibodies
Immunoassay (IA) 1 Antibodies
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Immunocytochemistry (ICC) 22 Antibodies
Immunofluorescence (IF) 23 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 77 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 68 Antibodies
Immunoprecipitation (IP) 44 Antibodies
Immunostaining (ISt) 1 Antibodies

General

Antigen Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
Epitope C-Term
(47), (18), (18), (17), (13), (10), (10), (8), (8), (7), (7), (6), (6), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(342), (96), (69), (19), (18), (14), (4), (1), (1), (1)
Host Rabbit
(271), (104), (11), (2)
Clonality
Polyclonal
Conjugate This Caspase 8 antibody is un-conjugated
(18), (12), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(326), (114), (81), (69), (42), (34), (31), (23), (12), (11), (8), (5), (2), (2), (1), (1), (1), (1), (1), (1)
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Product Details anti-Caspase 8 Antibody

Target Details Caspase 8 Application Details Handling Images
Specificity This antibody reacts to Caspase 8 (CASP8).
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Immunoaffinity Chromatography
Immunogen CASP8 antibody was raised against synthetic peptide - KLH conjugated

Target Details Caspase 8

Product Details anti-Caspase 8 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Caspase-8 (CASP8 Antibody Abstract)
Background Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase-8 is an initiator caspase that was identified as a member of the Fas/APO-1 death-inducing signaling complex. The adaptor molecule FADD couples procaspase-8 to the Fas receptor death domain, subsequent oligomerization promotes procaspase-8 autoactivation. FLIP, a catalytically inactive caspase-8-like molecule inhibits these interactions and thus can inhibit apoptosis.Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, CASP-8, CASP8, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, ICE-like apoptotic protease 5, MCH5, MORT1-associated CED-3 homolog
Gene ID 841
NCBI Accession NP_001073593
UniProt Q14790
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling

Application Details

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer PBS containing 0.02 % sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Images

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling back to top
Supplier Images
Immunofluorescence (IF) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (C-Term) (ABIN615326) Immunocytochemistry of caspase-8 in Jurkat cells with caspase-8 antibody at 2 µg/ml.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (C-Term) (ABIN615326) Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (C-Term) (ABIN615326) Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western Blotting (WB) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (C-Term) (ABIN615326) Western blot analysis of caspase-8 in Jurkat cell lysate with caspase-8 antibody at (...