anti-Rat (Rattus) Caspase 8 antibody for Immunohistochemistry

Recommended Caspase 8 Antibody (supplied by: Log in to see )

Antigen
Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
  • casp8-A
  • xCaspase-8
  • casp8
  • CASP8
  • CASP-8
  • FLICE
  • MACH
  • Mch5
  • ALPS2B
  • CAP4
  • Casp-8
  • MCH5
  • caspase-8
  • zgc:92075
  • caspase 8, apoptosis-related cysteine peptidase
  • death related ced-3/Nedd2-like protein
  • caspase-8
  • caspase 8
  • casp8
  • Dredd
  • CASP8
  • AaeL_AAEL014148
  • LOC100222284
  • Casp8
  • LOC100348477
Epitope
Large Subunit, Small Subunit, active
43
19
18
16
15
12
10
10
8
8
7
6
6
6
5
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Gerbil, Human, Mouse (Murine), Rat (Rattus)
359
119
94
25
21
20
2
2
1
Host
Rabbit
277
115
10
2
Clonality
Polyclonal
Conjugate
This Caspase 8 antibody is un-conjugated
18
13
8
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
360
109
91
78
50
36
35
27
14
13
8
8
6
5
2
2
2
1
1
1
1
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Catalog No. ABIN252118
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.894933 ABIN969003 FACS IHC ELISA WB Mouse IgG1 Log in to see 1H11 2
8.894933 ABIN1531215 IHC ELISA WB Rabbit IgG pSer347 Log in to see Polyclonal
8.894933 ABIN1532233 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
8.894933 ABIN3181527 IHC WB Mouse IgG1 Log in to see 2G12
8.894933 ABIN2705694 IHC WB Rabbit Center Log in to see Polyclonal
8.894933 ABIN3188046 IHC WB Rabbit IgG Log in to see Polyclonal
8.894933 ABIN4288165 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal
8.894933 ABIN2852721 IHC WB Rabbit Log in to see Polyclonal
8.894933 ABIN2852720 IHC WB Mouse Log in to see
8.894933 ABIN1846137 FACS IHC ELISA WB Mouse IgG1 Log in to see
1 ABIN4288172 ICC IF IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 1
1 ABIN4288161 IHC IHC (fro) IHC (p) IP WB Rabbit AA 449-464, AA 464-479, AA 481-496, AA 523-538, C-Term Log in to see Polyclonal 3
1 ABIN3183671 ELISA IHC WB Rabbit IgG Ser2 Log in to see Polyclonal
1 ABIN3181944 ELISA IHC WB Rabbit IgG pSer347 Log in to see Polyclonal
1 ABIN4288173 ELISA FACS IHC IHC (p) WB Mouse IgG1 Log in to see 1H11
1 ABIN4903139 IF IHC IP WB Mouse IgG Log in to see
1 ABIN4880223 ELISA FACS IHC WB Mouse IgG1 Log in to see 1H11
1 ABIN1585723 IHC ELISA WB Rabbit C-Term Log in to see Polyclonal
1 ABIN1885811 IF IHC WB Rabbit AA 1-227 Log in to see Polyclonal
1 ABIN4278125 ICC IF IHC IHC (fro) IHC (p) IP WB Rabbit Large Subunit, Small Subunit, active Log in to see Polyclonal

General

Antigen Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
Epitope Large Subunit, Small Subunit, active
(43), (19), (18), (16), (15), (12), (10), (10), (8), (8), (7), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Gerbil, Human, Mouse (Murine), Rat (Rattus)
(359), (119), (94), (25), (21), (20), (2), (2), (1)
Host Rabbit
(277), (115), (10), (2)
Clonality
Polyclonal
Conjugate This Caspase 8 antibody is un-conjugated
(18), (13), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(360), (109), (91), (78), (50), (36), (35), (27), (14), (13), (8), (8), (6), (5), (2), (2), (2), (1), (1), (1), (1)
Pubmed 20 references available
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Product Details anti-Caspase 8 Antibody

Target Details Caspase 8 Application Details Handling ProductDetails: References for anti-Caspase 8 antibody (ABIN252118) Images
Specificity This is specific for the active (cleaved) Caspase 8 protein, both large (17-21 kDa) and small (10-13 kDa) subunits.
Purification Unpurified
Immunogen Recombinant catalytically active human Caspase-8 protein was used as immunogen.

Target Details Caspase 8

Product Details anti-Caspase 8 Antibody Application Details Handling ProductDetails: References for anti-Caspase 8 antibody (ABIN252118) Images back to top
Antigen
Alternative Name Caspase-8 (CASP8 Antibody Abstract)
Background Gene Symbol: CASP8
Molecular Weight Theoretical MW: 55.4 kDa
Gene ID 841
UniProt Q14790
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades

Application Details

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Handling ProductDetails: References for anti-Caspase 8 antibody (ABIN252118) Images back to top
Application Notes Western Blot 1:1000-1:2000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunoprecipitation 1:50-1:200, Immunohistochemistry-Paraffin 1:1000-1:5000, Immunohistochemistry-Frozen 1:10-1:500The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Handling

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details ProductDetails: References for anti-Caspase 8 antibody (ABIN252118) Images back to top
Format Liquid
Buffer Whole antisera
Buffer contains: 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.

ProductDetails: References for anti-Caspase 8 antibody (ABIN252118)

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling Images back to top
Product cited in:

Chi, Hua, Chen, Bian, Yuan, Zhang, Wang, Chen, Deng, Li, Liu, de Paiva, Pflugfelder, Li: "Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye." in: Journal of autoimmunity, Vol. 80, pp. 65-76, 2017 Method employed by authors: Immunofluorescence (fixed cells) (IF/ICC) (Sample species: Mouse (Murine)).

Gao, Yang, Fan, Li, Fang, Yang: "Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis." in: Mediators of inflammation, Vol. 2016, pp. 1320365, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

Xiao, Yao, Jia, Lin, Zacks: "Protective Effect of Met12, a Small Peptide Inhibitor of Fas, on the Retinal Pigment Epithelium and Photoreceptor After Sodium Iodate Injury." in: Investigative ophthalmology & visual science, Vol. 58, Issue 3, pp. 1801-1810, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

Matzke-Ogi, Jannasch, Shatirishvili, Fuchs, Chiblak, Morton, Tawk, Lindner, Sansom, Alves, Warth, Schwager, Mier, Kleeff, Ponta, Abdollahi, Orian-Rousseau: "Inhibition of Tumor Growth and Metastasis in Pancreatic Cancer Models by Interference With CD44v6 Signaling." in: Gastroenterology, Vol. 150, Issue 2, pp. 513-25.e10, 2016

Cheng, Cheng, Chang, Chen, Wu, Hsieh: "Dodecyl gallate induces apoptosis by upregulating the caspase-dependent apoptotic pathway and inhibiting the expression of anti-apoptotic Bcl-2 family proteins in human osteosarcoma cells." in: Molecular medicine reports, Vol. 13, Issue 2, pp. 1495-500, 2016 (Sample species: Human). Further details: Western Blotting

Fan, Li, Yao, Deng, Liu, Cui, Wang, Wu, Deng: "Neural differentiation and synaptogenesis in retinal development." in: Neural regeneration research, Vol. 11, Issue 2, pp. 312-8, 2016 (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Wu, Cheng, Lee, Chang, Chen, Hsieh, Chueh: "Ursolic Acid Triggers Apoptosis in Human Osteosarcoma Cells via Caspase Activation and the ERK1/2 MAPK Pathway." in: Journal of agricultural and food chemistry, Vol. 64, Issue 21, pp. 4220-6, 2016 (Sample species: Human). Further details: Western Blotting

Magarin, Pohl, Lill, Schulz, Blaschke, Heuser, Thierfelder, Donath, Drenckhahn: "Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress." in: Journal of molecular and cellular cardiology, Vol. 97, pp. 1-14, 2016 (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Paraffin-embedded Sections)

El-Hawary, Abdel-Halim, Sayed, Abdelkader: "Apocytolysis, a proposed mechanism of blister formation in epidermolysis bullosa simplex." in: Archives of dermatological research, Vol. 307, Issue 4, pp. 371-7, 2015 (Sample species: Human). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Seko, Fujimura, Yao, Taka, Mineki, Okumura, Murayama: "Secreted tyrosine sulfated-eIF5A mediates oxidative stress-induced apoptosis." in: Scientific reports, Vol. 5, pp. 13737, 2015 (Sample species: Rat (Rattus)). Further details: Western Blotting

Wang, Wu, Wang, Deng, Ma, Fan, He, Deng: "Prenatal alcohol exposure inducing the apoptosis of mossy cells in hippocampus of SMS2-/- mice." in: Environmental toxicology and pharmacology, Vol. 40, Issue 3, pp. 975-82, 2015 (Sample species: Mouse (Murine)). Further details: Western Blotting,Immunohistochemistry (Paraffin-embedded Sections)

Thamizhiniyan, Young-Woong, Young-Kyoon: "The cytotoxic nature of Acanthopanax sessiliflorus stem bark extracts in human breast cancer cells." in: Saudi journal of biological sciences, Vol. 22, Issue 6, pp. 752-9, 2015 (Sample species: Human).

Kasloff, Pizzuto, Silic-Benussi, Pavone, Ciminale, Capua: "Oncolytic activity of avian influenza virus in human pancreatic ductal adenocarcinoma cell lines." in: Journal of virology, Vol. 88, Issue 16, pp. 9321-34, 2014 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Garraway, Woller, Huie, Hartman, Hook, Miranda, Huang, Ferguson, Grau: "Peripheral noxious stimulation reduces withdrawal threshold to mechanical stimuli after spinal cord injury: role of tumor necrosis factor alpha and apoptosis." in: Pain, Vol. 155, Issue 11, pp. 2344-59, 2014 Method employed by authors: Immunofluorescence (IF)

Zhang, De Paiva, Su, Volpe, Li, Pflugfelder: "Topical interferon-gamma neutralization prevents conjunctival goblet cell loss in experimental murine dry eye." in: Experimental eye research, Vol. 118, pp. 117-24, 2013 (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Frozen Sections)

Tauber, Harms, Falkenburger, Weis, Sellhaus, Nau, Schulz, Reich: "Modulation of hippocampal neuroplasticity by Fas/CD95 regulatory protein 2 (Faim2) in the course of bacterial meningitis." in: Journal of neuropathology and experimental neurology, Vol. 73, Issue 1, pp. 2-13, 2013 (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Niu, Li, Zang, Huang, Deng, Cui, Yu, Deng: "Death receptor 5 and neuroproliferation." in: Cellular and molecular neurobiology, Vol. 32, Issue 2, pp. 255-65, 2012

Herold, Rennekampff, Ohm, Strauss, Linkner, Reimers, Allmeling, Vaske, Vogt: "Apoptosis in extracorporeal preserved inguinal fat flaps of the rat." in: Apoptosis : an international journal on programmed cell death, Vol. 17, Issue 4, pp. 400-9, 2012 (Sample species: Rat (Rattus)). Further details: Immunocytochemistry,Immunofluorescence,Immunohistochemistry

Yang, Wu, Cao, Huang, Zhu, Tang, Dai: "Pathways of macrophage apoptosis within the interface membrane in aseptic loosening of prostheses." in: Biomaterials, Vol. 32, Issue 35, pp. 9159-67, 2011

Csak, Dolganiuc, Kodys, Nath, Petrasek, Bala, Lippai, Szabo: "Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice." in: Hepatology (Baltimore, Md.), Vol. 53, Issue 6, pp. 1917-31, 2011 Further details: Western Blotting

Images

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling ProductDetails: References for anti-Caspase 8 antibody (ABIN252118) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) (Large Subunit), (Small Subunit), (active) antibody (ABIN252118) Immunohistochemistry: Active/Cleaved Caspase-8 Antibody [ABIN252118] - Formalin-fixed...
Immunohistochemistry (IHC) image for anti-Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) (Large Subunit), (Small Subunit), (active) antibody (ABIN252118) Immunohistochemistry: Active/Cleaved Caspase-8 Antibody [ABIN252118] - Formalin-fixed...
Western Blotting (WB) image for anti-Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) (Large Subunit), (Small Subunit), (active) antibody (ABIN252118) Western Blot: active/cleaved Caspase 8 Antibody [ABIN2521186] - Analysis of active/cl...