You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Rat (Rattus) Caspase 8 antibody for Immunohistochemistry (Frozen Sections)

Recommended Caspase 8 Antibody (supplied by: Log in to see )

Antigen
Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
  • ALPS2B
  • CAP4
  • Casp-8
  • CASP-8
  • casp8
  • CASP8
  • casp8-A
  • caspase-8
  • FLICE
  • MACH
  • Mch5
  • MCH5
  • xCaspase-8
  • zgc:92075
Epitope
Large Subunit, Small Subunit, active
46
19
18
17
14
10
10
8
8
7
7
6
6
5
5
5
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Gerbil, Human, Mouse (Murine), Rat (Rattus)
345
101
74
19
18
16
1
1
1
1
Host
Rabbit
269
107
10
2
Clonality
Polyclonal
Conjugate
This Caspase 8 antibody is un-conjugated
18
12
8
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
327
115
84
70
42
37
31
25
13
12
12
8
5
2
2
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN252118
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008871543 ABIN4288161 IHC IHC (fro) IHC (p) IP WB Rabbit AA 449-464, AA 464-479, AA 481-496, AA 523-538, C-Term Log in to see Polyclonal 3
0.0008871543 ABIN4288160 IHC IHC (fro) IHC (p) IP WB Rabbit AA 449-464, AA 464-479, AA 481-496, AA 523-538, C-Term Log in to see Polyclonal
0.0008871543 ABIN1862286 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-Caspase 8 antibody for Immunohistochemistry (Frozen Sections)

Similar anti-Caspase 8 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 17 Antibodies 32 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 4 Antibodies
Flow Cytometry (FACS) 6 Antibodies 10 Antibodies
Immunocytochemistry (ICC) 8 Antibodies 12 Antibodies
Immunofluorescence (IF) 7 Antibodies 7 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 12 Antibodies 12 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 12 Antibodies 12 Antibodies
Immunohistochemistry (IHC) 32 Antibodies 34 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 15 Antibodies
Immunoprecipitation (IP) 8 Antibodies
Western Blotting (WB) 59 Antibodies

General

Antigen Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
Epitope Large Subunit, Small Subunit, active
(46), (19), (18), (17), (14), (10), (10), (8), (8), (7), (7), (6), (6), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Gerbil, Human, Mouse (Murine), Rat (Rattus)
(345), (101), (74), (19), (18), (16), (1), (1), (1), (1)
Host Rabbit
(269), (107), (10), (2)
Clonality
Polyclonal
Conjugate This Caspase 8 antibody is un-conjugated
(18), (12), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(327), (115), (84), (70), (42), (37), (31), (25), (13), (12), (12), (8), (5), (2), (2), (1), (1), (1), (1), (1)
Pubmed 20 references available
Supplier Log in to see

Product Details anti-Caspase 8 Antibody

Target Details Caspase 8 Application Details Handling References for anti-Caspase 8 Antibody (ABIN252118) Images
Specificity This is specific for the active (cleaved) Caspase 8 protein, both large (17-21 kDa) and small (10-13 kDa) subunits.
Cross-Reactivity (Details) May react with dog.
Purification Unpurified
Immunogen Recombinant catalytically active human Caspase-8 protein was used as immunogen.
Isotype IgG

Target Details Caspase 8

Product Details anti-Caspase 8 Antibody Application Details Handling References for anti-Caspase 8 Antibody (ABIN252118) Images back to top
Antigen
Alternative Name Caspase-8 (CASP8 Antibody Abstract)
Background Gene Symbol: CASP8
Molecular Weight Theoretical MW: 55.4 kDa
UniProt Q14790
Pathways Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling

Application Details

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Handling References for anti-Caspase 8 Antibody (ABIN252118) Images back to top
Application Notes Western Blot 1:1000-1:2000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunoprecipitation 1:50-1:200, Immunohistochemistry-Paraffin 1:1000-1:5000, Immunohistochemistry-Frozen 1:10-1:500
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Handling

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details References for anti-Caspase 8 Antibody (ABIN252118) Images back to top
Format Liquid
Buffer Whole antiserum
Buffer contains: 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.

References for anti-Caspase 8 Antibody (ABIN252118)

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling Images back to top
Product cited in:

Matzke-Ogi, Jannasch, Shatirishvili, Fuchs, Chiblak, Morton, Tawk, Lindner, Sansom, Alves, Warth, Schwager, Mier, Kleeff, Ponta, Abdollahi, Orian-Rousseau: "Inhibition of Tumor Growth and Metastasis in Pancreatic Cancer Models by Interference With CD44v6 Signaling." in: Gastroenterology, Vol. 150, Issue 2, pp. 513-25.e10, 2016

Cheng, Cheng, Chang, Chen, Wu, Hsieh: "Dodecyl gallate induces apoptosis by upregulating the caspase-dependent apoptotic pathway and inhibiting the expression of anti-apoptotic Bcl-2 family proteins in human osteosarcoma cells." in: Molecular medicine reports, Vol. 13, Issue 2, pp. 1495-500, 2016 (Sample species: Human). Further details: Western Blotting

Fan, Li, Yao, Deng, Liu, Cui, Wang, Wu, Deng: "Neural differentiation and synaptogenesis in retinal development." in: Neural regeneration research, Vol. 11, Issue 2, pp. 312-8, 2016 (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Wu, Cheng, Lee, Chang, Chen, Hsieh, Chueh: "Ursolic Acid Triggers Apoptosis in Human Osteosarcoma Cells via Caspase Activation and the ERK1/2 MAPK Pathway." in: Journal of agricultural and food chemistry, Vol. 64, Issue 21, pp. 4220-6, 2016 (Sample species: Human). Further details: Western Blotting

Magarin, Pohl, Lill, Schulz, Blaschke, Heuser, Thierfelder, Donath, Drenckhahn: "Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress." in: Journal of molecular and cellular cardiology, Vol. 97, pp. 1-14, 2016 (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Paraffin-embedded Sections)

El-Hawary, Abdel-Halim, Sayed, Abdelkader: "Apocytolysis, a proposed mechanism of blister formation in epidermolysis bullosa simplex." in: Archives of dermatological research, Vol. 307, Issue 4, pp. 371-7, 2015 (Sample species: Human). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Seko, Fujimura, Yao, Taka, Mineki, Okumura, Murayama: "Secreted tyrosine sulfated-eIF5A mediates oxidative stress-induced apoptosis." in: Scientific reports, Vol. 5, pp. 13737, 2015 (Sample species: Rat (Rattus)). Further details: Western Blotting

Wang, Wu, Wang, Deng, Ma, Fan, He, Deng: "Prenatal alcohol exposure inducing the apoptosis of mossy cells in hippocampus of SMS2-/- mice." in: Environmental toxicology and pharmacology, Vol. 40, Issue 3, pp. 975-82, 2015 (Sample species: Mouse (Murine)). Further details: Western Blotting,Immunohistochemistry (Paraffin-embedded Sections)

Thamizhiniyan, Young-Woong, Young-Kyoon: "The cytotoxic nature of Acanthopanax sessiliflorus stem bark extracts in human breast cancer cells." in: Saudi journal of biological sciences, Vol. 22, Issue 6, pp. 752-9, 2015 (Sample species: Human).

Kasloff, Pizzuto, Silic-Benussi, Pavone, Ciminale, Capua: "Oncolytic activity of avian influenza virus in human pancreatic ductal adenocarcinoma cell lines." in: Journal of virology, Vol. 88, Issue 16, pp. 9321-34, 2014 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Garraway, Woller, Huie, Hartman, Hook, Miranda, Huang, Ferguson, Grau: "Peripheral noxious stimulation reduces withdrawal threshold to mechanical stimuli after spinal cord injury: role of tumor necrosis factor alpha and apoptosis." in: Pain, Vol. 155, Issue 11, pp. 2344-59, 2014 Method employed by authors: Immunofluorescence (IF)

Zhang, De Paiva, Su, Volpe, Li, Pflugfelder: "Topical interferon-gamma neutralization prevents conjunctival goblet cell loss in experimental murine dry eye." in: Experimental eye research, Vol. 118, pp. 117-24, 2013 (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Frozen Sections)

Tauber, Harms, Falkenburger, Weis, Sellhaus, Nau, Schulz, Reich: "Modulation of hippocampal neuroplasticity by Fas/CD95 regulatory protein 2 (Faim2) in the course of bacterial meningitis." in: Journal of neuropathology and experimental neurology, Vol. 73, Issue 1, pp. 2-13, 2013 (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Niu, Li, Zang, Huang, Deng, Cui, Yu, Deng: "Death receptor 5 and neuroproliferation." in: Cellular and molecular neurobiology, Vol. 32, Issue 2, pp. 255-65, 2012

Herold, Rennekampff, Ohm, Strauss, Linkner, Reimers, Allmeling, Vaske, Vogt: "Apoptosis in extracorporeal preserved inguinal fat flaps of the rat." in: Apoptosis : an international journal on programmed cell death, Vol. 17, Issue 4, pp. 400-9, 2012 (Sample species: Rat (Rattus)). Further details: Immunocytochemistry,Immunofluorescence,Immunohistochemistry

Yang, Wu, Cao, Huang, Zhu, Tang, Dai: "Pathways of macrophage apoptosis within the interface membrane in aseptic loosening of prostheses." in: Biomaterials, Vol. 32, Issue 35, pp. 9159-67, 2011

Csak, Dolganiuc, Kodys, Nath, Petrasek, Bala, Lippai, Szabo: "Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice." in: Hepatology (Baltimore, Md.), Vol. 53, Issue 6, pp. 1917-31, 2011 Further details: Western Blotting

Zhang, Chen, De Paiva, Corrales, Volpe, McClellan, Farley, Li, Pflugfelder: "Interferon-? exacerbates dry eye-induced apoptosis in conjunctiva through dual apoptotic pathways." in: Investigative ophthalmology & visual science, Vol. 52, Issue 9, pp. 6279-85, 2011

Anand, Wilson, Hasan, Maytin: "Vitamin D3 enhances the apoptotic response of epithelial tumors to aminolevulinate-based photodynamic therapy." in: Cancer research, Vol. 71, Issue 18, pp. 6040-50, 2011

Krajewska, You, Rong, Kress, Huang, Yang, Kyoda, Leyva, Banares, Hu, Sze, Whalen, Salmena, Hakem, Head, Reed, Krajewski: "Neuronal deletion of caspase 8 protects against brain injury in mouse models of controlled cortical impact and kainic acid-induced excitotoxicity." in: PLoS ONE, Vol. 6, Issue 9, pp. e24341, 2011 (Sample species: Mouse (Murine)). Further details: Western Blotting

Images

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling References for anti-Caspase 8 Antibody (ABIN252118) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (Large Subunit) (ABIN252118) Immunohistochemistry: Active/Cleaved Caspase-8 Antibody [ABIN252118] - Formalin-fixed...
Immunohistochemistry (IHC) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (Large Subunit) (ABIN252118) Immunohistochemistry: Active/Cleaved Caspase-8 Antibody [ABIN252118] - Formalin-fixed...
Western Blotting (WB) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (Large Subunit) (ABIN252118) Western Blot: active/cleaved Caspase 8 Antibody [ABIN2521186] - Analysis of active/cl...