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anti-Mouse (Murine) CFLAR antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CFLAR Antibody (supplied by: Log in to see )

Antigen
CASP8 and FADD-Like Apoptosis Regulator (CFLAR) Antibodies
  • 2310024N18Rik
  • A430105C05Rik
  • c-Flip
  • c-FLIP
  • c-FLIPL
  • c-FLIPR
  • c-FLIPS
  • CASH
  • Cash
  • CASP8AP1
  • Casper
  • cflar
  • CFLAR
  • CLARP
  • Clarp1
  • ENSMUSG00000072980
  • FLAME
  • FLAME-1
  • FLAME1
  • Flip
  • FLIP
  • Gm9845
  • I-FLICE
  • MRIT
Epitope
C-Term, long form
38
24
21
19
13
13
13
10
8
7
6
6
6
5
4
4
3
3
3
2
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
251
102
76
2
2
2
2
2
1
Host
Rabbit
167
81
23
Clonality
Polyclonal
Conjugate
This CFLAR antibody is un-conjugated
9
6
5
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
230
97
59
41
39
28
22
18
14
8
5
3
1
1
1
Supplier
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Catalog No. ABIN1106673
$ 313.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008985059 ABIN401040 IHC (p) WB Rabbit IgG Log in to see Polyclonal 4
0.0008985059 ABIN725255 IF (p) IHC (p) WB Rabbit IgG AA 1-50 Log in to see Polyclonal
0.0008985059 ABIN737946 IF (p) IHC (p) WB Rabbit IgG AA 462-480 Log in to see Polyclonal
0.0008985059 ABIN725257 IHC (p) WB Biotin Rabbit IgG AA 1-50 Log in to see Polyclonal
0.0008985059 ABIN725264 IHC (p) WB HRP Rabbit IgG AA 1-50 Log in to see Polyclonal
0.0008985059 ABIN737948 IHC (p) WB Biotin Rabbit IgG AA 462-480 Log in to see Polyclonal
0.0008985059 ABIN737955 IHC (p) WB HRP Rabbit IgG AA 462-480 Log in to see Polyclonal
0.0008985059 ABIN1858388 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 210-460 Log in to see Polyclonal
0.0008985059 ABIN1733023 ICC IHC (p) ELISA WB Rabbit IgG AA 191-209 Log in to see Polyclonal
0.0008985059 ABIN4312113 ELISA ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal

Top referenced anti-CFLAR antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-CFLAR Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 219 Antibodies 81 Antibodies 56 Antibodies
SDS-PAGE (SDS) 1 Antibodies 1 Antibodies 1 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunoprecipitation (IP) 18 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 39 Antibodies 11 Antibodies 8 Antibodies
Immunohistochemistry (IHC) 59 Antibodies 15 Antibodies 11 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies 2 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies 22 Antibodies

General

Antigen CASP8 and FADD-Like Apoptosis Regulator (CFLAR) Antibodies
Epitope C-Term, long form
(38), (24), (21), (19), (13), (13), (13), (10), (8), (7), (6), (6), (6), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(251), (102), (76), (2), (2), (2), (2), (2), (1)
Host Rabbit
(167), (81), (23)
Clonality
Polyclonal
Conjugate This CFLAR antibody is un-conjugated
(9), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(230), (97), (59), (41), (39), (28), (22), (18), (14), (8), (5), (3), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-CFLAR Antibody

Target Details CFLAR Application Details Handling References for anti-CFLAR Antibody (ABIN1106673) Images
Specificity Recognizes FLIP-L No cross reactivity with other proteins.
Purification Immunoaffinity Chromatography
Immunogen A synthetic peptide corresponding to a sequence mapping at the C-terminal of Human FLIP- L, identical to the related Mouse sequence.
Isotype IgG

Target Details CFLAR

Product Details anti-CFLAR Antibody Application Details Handling References for anti-CFLAR Antibody (ABIN1106673) Images back to top
Antigen
Alternative Name CFLAR / Casper / I-FLICE (CFLAR Antibody Abstract)
Background Irmler et al. (1997) isolated human cDNAs encoding 2 isoforms of FLIP. FLIP(L), the longer isoform, contains 2 DEDs and a caspase-like domain, and FLIP(S), the shorter isoform, contains only the 2 DEDs followed by a C-terminal extension of approximately 50 amino acids. High levels of FLIP(L) protein were detected in melanoma cell lines and malignant melanoma tumors. FLIP may be implicated in tissue homeostasis as an important regulator of apoptosis.Synonyms: CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP
Gene ID 8837
NCBI Accession NP_001120655
UniProt O15519
Pathways Apoptosis

Application Details

Product Details anti-CFLAR Antibody Target Details CFLAR Handling References for anti-CFLAR Antibody (ABIN1106673) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details References for anti-CFLAR Antibody (ABIN1106673) Images back to top
Reconstitution Restore with 0.2 mL of distilled water to yield a concentration of 0.5 mg/mL.
Concentration 0.5 mg/mL
Buffer 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg Sodium Azide
Preservative Sodium azide, Thimerosal (Merthiolate)
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody after reconstitution at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-CFLAR Antibody (ABIN1106673)

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details Handling Images back to top
Background publications

Irmler, Thome, Hahne, Schneider, Hofmann, Steiner, Bodmer, Schröter, Burns, Mattmann, Rimoldi, French, Tschopp: "Inhibition of death receptor signals by cellular FLIP." in: Nature, Vol. 388, Issue 6638, pp. 190-5, 1997

Images

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details Handling References for anti-CFLAR Antibody (ABIN1106673) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-CFLAR antibody (CASP8 and FADD-Like Apoptosis Regulator) (C-Term) (ABIN1106673) Immunohistochemical FLIPL antibody staining of Human Mammary Cancer Paraffin Sections.