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anti-Human Clusterin antibody for Enzyme Immunoassay

Recommended Clusterin Antibody (supplied by: Log in to see )

Antigen
Clusterin (CLU) Antibodies
  • 40
  • AI893575
  • APO-J
  • APOJ
  • ApoJ
  • Cli
  • CLI
  • CLU
  • clu
  • CLU1
  • CLU2
  • D14Ucla3
  • DAG
  • GP80
  • gpIII
  • KUB1
  • LOC100136120
  • MGC53055
  • MGC89163
  • NA1/NA2
  • RATTRPM2B
  • SGP-2
  • Sgp-2
  • SGP2
  • Sgp2
  • SP-40
  • SP40
  • Sugp-2
  • TRPM-2
  • Trpm2
  • TRPM2
  • TRPM2B
  • Trpmb
  • xclu
  • zgc:73352
Reactivity
Human
300
60
56
19
18
5
4
3
2
1
Host
Mouse
167
141
73
8
5
2
Clonality
Monoclonal
Conjugate
This Clusterin antibody is un-conjugated
33
26
13
11
7
7
3
3
3
3
3
3
3
3
3
3
3
3
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
322
267
139
99
60
54
35
30
28
10
7
1
1
Supplier
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Catalog No. ABIN238421
$ 286.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008867729 ABIN950467 EIA FACS IHC (p) WB Rabbit Ig AA 71-99, N-Term Log in to see Polyclonal 1
0.0008867729 ABIN317504 EIA IHC (p) WB Mouse IgG1 AA 1-333, N-Term Log in to see 1A11 4
0.0008867729 ABIN114700 EIA IHC (fro) IF WB Mouse IgG1 Log in to see Hs-3 3
0.0008867729 ABIN499644 EIA IHC (p) WB Rabbit IgG Isoform 1 Log in to see Polyclonal 4
0.0008867729 ABIN181112 EIA FACS IHC (fro) WB Mouse IgG1 Log in to see 3R3-2 2
0.0008867729 ABIN614876 EIA IHC (p) WB Goat C-Term Log in to see Polyclonal
0.0008867729 ABIN116548 EIA IHC (fro) IHC (p) IP WB Goat Log in to see Polyclonal
0.0008867729 ABIN2716300 EIA IHC (p) WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-Clusterin antibody for Enzyme Immunoassay

Similar anti-Clusterin Antibodies

Application / Reactivity Human
ELISA 197 Antibodies
Enzyme Immunoassay (EIA) 9 Antibodies
Flow Cytometry (FACS) 28 Antibodies
Immunochromatography (IC) 5 Antibodies
Immunocytochemistry (ICC) 47 Antibodies
Immunofluorescence (IF) 52 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 130 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 25 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 91 Antibodies
Immunoprecipitation (IP) 29 Antibodies
Western Blotting (WB) 260 Antibodies

General

Antigen Clusterin (CLU) Antibodies
Reactivity Human
(300), (60), (56), (19), (18), (5), (4), (3), (2), (1)
Host Mouse
(167), (141), (73), (8), (5), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Clusterin antibody is un-conjugated
(33), (26), (13), (11), (7), (7), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(322), (267), (139), (99), (60), (54), (35), (30), (28), (10), (7), (1), (1)
Pubmed 6 references available
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Product Details anti-Clusterin Antibody

Target Details Clusterin Application Details Handling References for anti-Clusterin Antibody (ABIN238421) Images
Specificity Recognizes Apolipoprotein J (Apo J).
Cross-Reactivity (Details) Species reactivity (tested):Human. Negative in Bovine, Canine (Dog) and Feline (Cat).
Characteristics Synonyms: Clusterin, APOJ, CLI, KUB1, AAG4, NA1/NA2, SP-40, 40, Complement-associated proteinSP-40, Complement cytolysis inhibitor, Testosterone-repressed prostate message 2,Ku70-binding protein 1, Aging-associated gene 4 protein
Purification Affinity Chromatography on Protein A
Immunogen Freshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid,10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0. 2% acetic acid and subsequently used forimmunization.
Clone Hs-3
Isotype IgG1

Target Details Clusterin

Product Details anti-Clusterin Antibody Application Details Handling References for anti-Clusterin Antibody (ABIN238421) Images back to top
Antigen
Alternative Name Apolipoprotein J (Apo J) (CLU Antibody Abstract)
Background Clusterin (APO J, SGP-2, TRPM-2, SP-40, pADHC-9, CLJ, T64, GP III, XIP8) is a 75-80 kD disulfide-linked heterodimeric protein containing about 30 % of N-linked carbohydrate rich in sialic acid but truncated forms targeted to the nucleus have also been identified. It is a conserved secreted glycoprotein expressed by a wide range of tissues and being implicated in many physiological processes, including e.g. lipid transportation, complement inhibition, tissue remodeling, membrane recycling, or clearence of cellular debris. It is nearly ubiqitously expressed in most mammalian tissues and can be found in plasma, milk, urine, cerebrospinal fluid and semen. Clusterin is able to bind and form complexes with numerous partners (immunoglobulins, lipids, heparin, bacteria, complement components, paraoxonase, beta amyloid, leptin etc.) and is expressed in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity and others. A genuine function of clusterin is still enigmatic.Synonyms: 40, 40, AAG4, APOJ, Aging-associated gene 4 protein, CLI, Clusterin, Complement cytolysis inhibitor, Complement-associated protein SP-40, KUB1, Ku70-binding protein 1, NA1/NA2, SP-40, Testosterone-repressed prostate message 2
Gene ID 1191
UniProt P10909
Research Area Metabolism, Receptors
Pathways Apoptosis

Application Details

Product Details anti-Clusterin Antibody Target Details Clusterin Handling References for anti-Clusterin Antibody (ABIN238421) Images back to top
Application Notes ELISA. Western blot: 1/ μg/mLPositive Material: seminal plasmaImmunocytochemistry. Immunohistochemistry on Paraffin Sections: 10 μg/mL. Positive Tissue: Sertoli cells.
Restrictions For Research Use only

Handling

Product Details anti-Clusterin Antibody Target Details Clusterin Application Details References for anti-Clusterin Antibody (ABIN238421) Images back to top
Concentration 1.0 mg/mL
Buffer PBS, pH ~7.4 with 15 mM Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months

References for anti-Clusterin Antibody (ABIN238421)

Product Details anti-Clusterin Antibody Target Details Clusterin Application Details Handling Images back to top
Background publications

Cochrane, Wang, Muramaki, Gleave, Nelson: "Differential regulation of clusterin and its isoforms by androgens in prostate cells." in: The Journal of biological chemistry, Vol. 282, Issue 4, pp. 2278-87, 2007

Schepeler, Mansilla, Christensen, Orntoft, Andersen: "Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling." in: Journal of molecular signaling, Vol. 2, pp. 6, 2007

Rodríguez-Piñeiro, de la Cadena, López-Saco, Rodríguez-Berrocal: "Differential expression of serum clusterin isoforms in colorectal cancer." in: Molecular & cellular proteomics : MCP, Vol. 5, Issue 9, pp. 1647-57, 2006

Pajak, Orzechowski: "Clusterin: the missing link in the calcium-dependent resistance of cancer cells to apoptogenic stimuli." in: Postȩpy higieny i medycyny doświadczalnej (Online), Vol. 60, pp. 45-51, 2006

Shannan, Seifert, Boothman, Tilgen, Reichrath: "Clusterin and DNA repair: a new function in cancer for a key player in apoptosis and cell cycle control." in: Journal of molecular histology, Vol. 37, Issue 5-7, pp. 183-8, 2006

Capková, Geussová, Peknicová: "New monoclonal antibody to human apolipoprotein J." in: Folia biologica, Vol. 48, Issue 1, pp. 40-2, 2002

Images

Product Details anti-Clusterin Antibody Target Details Clusterin Application Details Handling References for anti-Clusterin Antibody (ABIN238421) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Clusterin antibody (CLU) (ABIN238421) anti-Clusterin (CLU) antibody