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anti-Cow (Bovine) Perforin 1 antibody for Intracellular Staining

Recommended Perforin 1 Antibody (supplied by: Log in to see )

Antigen
Perforin 1 (Pore Forming Protein) (PRF1) Antibodies
  • Cyta
  • FLH2
  • HPLH2
  • LOC443187
  • P1
  • perforin
  • Pfn
  • PFN1
  • Pfp
  • PFP
  • Prf-1
  • prf1
  • PRF1
  • RATCYTA
Reactivity
Cow (Bovine), Human
161
48
20
18
1
1
Host
Mouse
107
72
28
Clonality
Monoclonal
Conjugate
This Perforin 1 antibody is un-conjugated
18
13
10
5
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Intracellular Staining (ICS), Immunoprecipitation (IP), Western Blotting (WB)
91
79
62
58
44
44
43
42
31
8
6
6
2
2
2
1
1
1
1
1
Supplier
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Catalog No. ABIN2689879
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General

Antigen Perforin 1 (Pore Forming Protein) (PRF1) Antibodies
Reactivity Cow (Bovine), Human
(161), (48), (20), (18), (1), (1)
Host Mouse
(107), (72), (28)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Perforin 1 antibody is un-conjugated
(18), (13), (10), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Intracellular Staining (ICS), Immunoprecipitation (IP), Western Blotting (WB)
(91), (79), (62), (58), (44), (44), (43), (42), (31), (8), (6), (6), (2), (2), (2), (1), (1), (1), (1), (1)
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Product Details anti-Perforin 1 Antibody

Target Details Perforin 1 Application Details Handling Images
Brand BD Pharmingen™
Characteristics Perforin has a key role in cell-mediated cytotoxicity. It is a 70 kDa cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. CTLs are involved in eliminating virally infected cells, in anti-tumor immune responses, in allograft rejections, and in some autoimmune diseases. NK cells are important for tumor surveillance and destruction and are involved in allograft rejections. Cytotoxic cells release the contents of their cytotoxic granules, including perforin upon recognition of their target cell. In the presence of calcium, perforin forms transmembrane channels or pores in the membrane of the target cell leading to a cell death that resembles apoptosis. The ability to detect perforin-positive cells with specific antibody should be useful in identifying and understanding perforin-mediated reactions.

BD Pharmingen™ Purified Mouse Anti-Human Perforin - Purified - Clone δG9 - Isotype Mouse IgG2b, κ - Reactivity Hu, Cow - 0.1 mg
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Purified Granules from the Human Lymphoma Cell Line YT
Clone DeltaG9
Isotype IgG2b, kappa

Target Details Perforin 1

Product Details anti-Perforin 1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Perforin (PRF1 Antibody Abstract)
Background Synonyms: PRF1, P1, PERF, PFN1, PFP, Perforin-1, Cytolysin, FLH2, HPLH2
Research Area Immunology, Innate Immunity, Adaptive Immunity, Inflammation
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-Perforin 1 Antibody Target Details Perforin 1 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Perforin 1 Antibody Target Details Perforin 1 Application Details Images back to top
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 4°C.