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Human Monoclonal CXCL1 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4900741
Meen, Øynebråten, Reine, Duelli, Svennevig, Pejler, Jenssen, Kolset: Serglycin is a major proteoglycan in polarized human endothelial cells and is implicated in the secretion of the chemokine GROalpha/CXCL1. in The Journal of biological chemistry 2011
Show all 5 Pubmed References
Human Monoclonal CXCL1 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4900740
Oladipo, Conlon, OGrady, Purcell, Wilson, Maxwell, Johnston, Stevenson, Kay, Wilson, Waugh: The expression and prognostic impact of CXC-chemokines in stage II and III colorectal cancer epithelial and stromal tissue. in British journal of cancer 2011
Show all 5 Pubmed References
Human Polyclonal CXCL1 Primary Antibody for WB - ABIN3044150
Xu, Zhu, Zhang, Tian, Zhang, Wu, Gao: NF?B-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice. in Journal of neuroinflammation 2014
Show all 2 Pubmed References
Human Polyclonal CXCL1 Primary Antibody for IHC, IHC (p) - ABIN4316223
Yeh, Shun, Kuo, Jung, Hsieh, Chiu, Chen, Hsu, Yang, Chia: Activated human valvular interstitial cells sustain interleukin-17 production to recruit neutrophils in infective endocarditis. in Infection and immunity 2015
Mouse (Murine) Polyclonal CXCL1 Primary Antibody for IF (p), IHC (p) - ABIN2173443
Ito, Katano, Kawai, Yagoto, Takahashi, Ka, Ogura, Takahashi, Ito: A Novel Xenogeneic Graft-Versus-Host Disease Model for Investigating the Pathological Role of Human CD4(+) or CD8(+) T Cells Using Immunodeficient NOG Mice. in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2016
Rat (Rattus) Polyclonal CXCL1 Primary Antibody for Func, ELISA - ABIN2473131
Vallès, Grijpink-Ongering, de Bree, Tuinstra, Ronken: Differential regulation of the CXCR2 chemokine network in rat brain trauma: implications for neuroimmune interactions and neuronal survival. in Neurobiology of disease 2006
Human Polyclonal CXCL1 Primary Antibody for ELISA - ABIN4274952
Kawanishi, Matsui, Ito, Watanabe, Takahashi, Nishizawa, Nishiyama, Kamoto, Mikami, Tanaka, Jung, Akiyama, Nobumasa, Guilford, Reeve, Okuno, Tsujimoto, Nakamura, Ogawa: Secreted CXCL1 is a potential mediator and marker of the tumor invasion of bladder cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008
this study demonstrates that in vivo blocking of CXCL1 and CXCL2 (show CXCL2 Antibodies) can significantly reduce the Mycobacterium tuberculosis-induced bioactive IL-1beta (show IL1B Antibodies) production
RelA (show NFkBP65 Antibodies) has a role in regulating OIS in preneoplastic lesions; the RelA (show NFkBP65 Antibodies)/CXCL1/CXCR2 (show CXCR2 Antibodies) axis is an essential mechanism of tumor surveillance in pancreatic ductal adenocarcinoma
CXCL1 contributed to rapid neutrophil recruitment during Bacillus cereus endophthalmitis. In CXCL1-knockout mice, retinal function was greater and neutrophil influx was less than in control mice, confirming its role in ocular inflammation.
Interferon-gamma (IFN-gamma (show IFNG Antibodies)) up-regulated interleukin 6 (IL-6 (show IL6 Antibodies)) and CXCL1 chemokine (show CCL1 Antibodies) (CXCL1) production of bone marrow mesenchymal stem cells (mBM-MSC (show MSC Antibodies)).
MMP7 (show MMP7 Antibodies) shedding of syndecan-1 (show SDC1 Antibodies)/CXCL1 complexes functions as a checkpoint that restricts neutrophil activation at sites of epithelial injury.
Data show that loss of loss of matrix metalloproteinase-3 (MMP-3 (show MMP3 Antibodies)) repressed the upregulation of the chemokines monocyte chemoattractant protein (MCP)-1 (show CPT1B Antibodies) and (C-X-C motif) ligand 1 (CXCL1).
CXCR2 (show CXCR2 Antibodies)/CXCL1 axis promotes granulocytic myeloid-derived suppressor cells recruitment and facilitates arginase I (show ARG1 Antibodies) expression and activity of these cells at maternal-fetal interface
The novel findings reveal the critical role of NLRP12 (show NLRP12 Antibodies)-IL-17A (show IL17A Antibodies)-CXCL1 axis in host defense by modulating neutrophil recruitment against Klebsiella pneumoniae.
Nlrp12 (show NLRP12 Antibodies) deficiency caused increased neutrophil migration towards the chemokine (show CCL1 Antibodies) CXCL1 and the neutrophil parasite Leishmania major, revealing NLRP12 (show NLRP12 Antibodies) as a negative regulator of directed neutrophil migration under these conditions.
CXCL1 monomer-dimer distribution and receptor interactions are highly coupled and regulate neutrophil trafficking and that injury in the context of disease is a consequence of inappropriate CXCR2 (show CXCR2 Antibodies) activation
Taken together, the present study indicates that IL-33 (show IL33 Antibodies) localized in the human atherosclerotic plaque increases GRO-alpha mRNA expression and protein secretion via activation of ERK1/2 (show MAPK1/3 Antibodies), JNK (show MAPK8 Antibodies), and NF-kappaB (show NFKB1 Antibodies) in HUVECs, suggesting that IL-33 (show IL33 Antibodies) plays an important role in the pathophysiology and development of atherosclerosis.
Study provides the first evidence that primary malignant cell-secreted VEGFA (show VEGFA Antibodies) stimulates tumor-associated macrophages to produce CXCL1, which recruits CXCR2 (show CXCR2 Antibodies)-positive MDSCs to form a premetastatic niche to promote liver metastases.
the presence of elevated circulating levels of VEGF (show VEGFA Antibodies) and CXCL1 are predictive of liver and lung metastasis, respectively of colorectal cancer.
This study describe elevated levels of CXCL1 and it receptor in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma, relative to other pediatric brain tumors and normal cerebral tissue.
The expressions of CXCL1 in cancer cells and CXCR2 (show CXCR2 Antibodies) in stromal cells are useful prognostic factors for gastric cancer patients
CXCL1 secreted by tumor-associated lymphatic endothelial cells promotes lymph node metastasis of gastric cancer through integrin beta1/FAK (show PTK2 Antibodies)/AKT (show AKT1 Antibodies) signaling pathway.
S100A9 (show S100A9 Antibodies) and S100A12 (show S100A12 Antibodies) may have a role in the pathogenesis of pneumonia: S100A9 (show S100A9 Antibodies) and CXCL1 may contribute solely in mild pneumonia, and CCL5 (show CCL5 Antibodies) and CXCL11 (show CXCL11 Antibodies) may contribute in severe pneumonia.
These findings support a role for CXCL1 and IL-8 (show IL8 Antibodies) in cystic fibrosis (show S100A8 Antibodies) lung disease severity and identify STAT3 (show STAT3 Antibodies) as a modulating pathway.
Results suggest that CXCL1 is a key molecular link between senescence of stromal fibroblasts and tumor growth.
Increased IL-8 (show IL8 Antibodies) and CXCL1 transcription in T84 and THP-1 (show GLI2 Antibodies) cells compared to that in wild-type EPEC.
This gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.
, growth-regulated alpha protein
, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
, melanoma growth stimulatory activity homolog
, C-X-C motif chemokine 1
, cytokine-induced neutrophil chemoattractant 1
, platelet-derived growth factor-inducible protein KC
, GRO1 oncogene
, secretory protein N51
, growth regulated protein GRO
, growth regulated
, GRO1 oncogene (melanoma growth stimulating activity, alpha)
, GRO1 oncogene (melanoma growth-stimulating activity)
, MGSA alpha
, fibroblast secretory protein
, melanoma growth stimulatory activity alpha
, neutrophil-activating protein 3
, growth related gene 1
, growth-regulated protein homolog alpha