Browse our RARRES2 Proteins (RARRES2)

Full name:
Retinoic Acid Receptor Responder (Tazarotene Induced) 2 Proteins (RARRES2)
On are 30 Retinoic Acid Receptor Responder (Tazarotene Induced) 2 (RARRES2) Proteins from 12 different suppliers available. Additionally we are shipping RARRES2 Antibodies (128) and RARRES2 Kits (58) and many more products for this protein. A total of 243 RARRES2 products are currently listed.
0610007L05Rik, AI303516, HP10433, TIG2
list all proteins Gene Name GeneID UniProt
RARRES2 5919 Q99969
RARRES2 71660 Q9DD06
RARRES2 297073  

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RARRES2 Proteins (RARRES2) by Origin

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More Proteins for RARRES2 Interaction Partners

Human Retinoic Acid Receptor Responder (Tazarotene Induced) 2 (RARRES2) interaction partners

  1. RARRES2 overexpression in adrenocortical carcinoma cells inhibited Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) pathway activity by promoting beta-catenin (show CTNNB1 Proteins) phosphorylation and degradation, it also inhibited the phosphorylation of p38 mitogen-activated protein kinase (show MAPK14 Proteins). Thus our study identifies RARRES2 as a novel tumor suppressor for adrenocortical carcinoma, which can function through an immune-independent mechanism.

  2. study reveals the tumor-inhibitory effect of chemerin by suppressing inflammatory tumor microenvironment with therapeutic implications for inflammation-associated cancer-like Hepatocellular carcinoma.

  3. Further analysis of chemerin functions in vivo might constitute a crucial step toward optimizing Mesenchymal stromal cells-based therapy for inflammatory diseases.

  4. Stimulation of mesenchymal stromal cells (MSCs) by chemerin increases phosphorylation of p42 (show EPB42 Proteins)/44, p38 (show CRK Proteins) and JNK (show MAPK8 Proteins)-II kinases and inhibitors of these kinases and PKC (show PRRT2 Proteins) reverse chemerin-stimulated MSC (show MSC Proteins) migration.

  5. Elevated chemerin levels in colons from ulcerative colitis patients correlate with disease severity

  6. cathepsin S (show CTSS Proteins) and chemerin only correlated positively with insulin (show INS Proteins) resistance and inflammation

  7. Cathepsin L (show CTSL1 PLURAL_@34956@)- and K-cleaved chemerin trigger robust migration of human blood-derived plasmacytoid dendritic cells ex vivo

  8. Plasma chemerin levels are correlated with obesity, blood pressure, and high-density lipoprotein cholesterol, suggesting that it may play a role in the pathogenesis of metabolic syndrome.

  9. High serum RARRES2 expression is associated with Adrenocortical Carcinoma.

  10. Hypoxia-induced chemerin expression is mediated by TNF-alpha (show TNF Proteins) and at least in part by the ERK (show EPHB2 Proteins) pathway

Mouse (Murine) Retinoic Acid Receptor Responder (Tazarotene Induced) 2 (RARRES2) interaction partners

  1. elevated levels of chemerin were found in colons of mice with experimental colitis, and a neutralizing anti-chemerin antibody improved intestinal inflammation

  2. Data suggest a potential role for chemerin and CMKLR1 (show CMKLR1 Proteins) in the regulation of inflammatory responses in the tumor microenvironment.

  3. Suggest reduction of chemerin could contribute to the antiobesity/antidiabetic properties described for alpha-lipoic acid.

  4. Study indicates that Chemerin plays a role in the negative cross-talk between skeletal muscle and adipose tissue. Specifically, Chemerin promotes the adipogenic differentiation potential and alters the myoblast cell fate from myogenesis to adipogenesis.

  5. Data indicate that chemerin may play an important role in regulating mitochondrial remodelling and function in skeletal muscle.

  6. The chemerin15 (C15) precursor, chemerin, and its receptor, ChemR23, are both upregulated after skin damage and the receptor is expressed by macrophages, neutrophils, and keratinocytes. C15 delivery dampens immediate inflammatory events.

  7. findings reveal previously uncharacterized regulators of chemerin expression in skin and identify a physiologic role for chemerin in skin barrier defense against microbial pathogens.

  8. A novel autocrine/paracrine role for chemerin in regulating osteoclast differentiation of hematopoietic stem cells

  9. this study reports that retinoic acid-activated endothelial cells can promote myeloid and plasmacytoid dendritic cell transmigration across endothelial cell monolayers through the endogenous production of chemerin

  10. Data suggest that chemerin/ChemR23 (chemokine-like receptor 1 (show CMKLR1 Proteins)) signaling is not essential for adipocyte differentiation, but it appears to play a role in control of body weight and energy metabolism as overweight/obesity progresses.

Pig (Porcine) Retinoic Acid Receptor Responder (Tazarotene Induced) 2 (RARRES2) interaction partners

  1. Chemerin regulates energy metabolism partly through the Akt and ERK1/2 signaling pathways.

Cow (Bovine) Retinoic Acid Receptor Responder (Tazarotene Induced) 2 (RARRES2) interaction partners

  1. These results suggest that Chemerin promotes lipolysis in mature adipocytes and induces adipogenesis during preadipocyte re-differentiation, further indicating a dual role for Chemerin in the deposition of intramuscular fat in ruminant animals.

  2. chemerin is a novel regulator of lactogenesis via its own receptor in bovine mammary epithelial cells

RARRES2 Protein Profile

Protein Summary

This gene encodes a secreted chemotactic protein that initiates chemotaxis via the ChemR23 G protein-coupled seven-transmembrane domain ligand. Expression of this gene is upregulated by the synthetic retinoid tazarotene and occurs in a wide variety of tissues. The active protein has several roles, including that as an adipokine, and is truncated on both termini from the proprotein.

Alternative names and synonyms associated with RARRES2

  • chemerin preproprotein-like (LOC100346066)
  • retinoic acid receptor responder (tazarotene induced) 2 (RARRES2)
  • retinoic acid receptor responder (tazarotene induced) 2 (Rarres2)
  • 0610007L05Rik protein
  • AI303516 protein
  • HP10433 protein
  • TIG2 protein

Protein level used designations for RARRES2

RAR-responsive protein TIG2 , chemerin , retinoic acid receptor responder protein 2 , tazarotene-induced gene 2 protein , CHO functionally unknown type II transmembrane protein , Tazarotene-induced gene 2 protein

100346066 Oryctolagus cuniculus
5919 Homo sapiens
71660 Mus musculus
297073 Rattus norvegicus
100141314 Sus scrofa
508990 Bos taurus
100689253 Cricetulus griseus
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