Browse our TJP1 Proteins (TJP1)

Full name:
Tight Junction Protein 1 (Zona Occludens 1) Proteins (TJP1)
On www.antibodies-online.com are 9 Tight Junction Protein 1 (Zona Occludens 1) (TJP1) Proteins from 4 different suppliers available. Additionally we are shipping TJP1 Antibodies (97) and TJP1 Kits (39) and many more products for this protein. A total of 151 TJP1 products are currently listed.
Synonyms:
ZO-1, zo1
list all proteins Gene Name GeneID UniProt
TJP1 7082 Q07157
Mouse TJP1 TJP1 21872 P39447
TJP1 292994  

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More Proteins for TJP1 Interaction Partners

Human Tight Junction Protein 1 (Zona Occludens 1) (TJP1) interaction partners

  1. Aberrant expression of the tight junction molecules claudin-1 (show CLDN7 Proteins) and zonula occludens-1 mediates cell growth and invasion in oral squamous cell carcinoma cells.

  2. ZO-1-occludin (show OCLN Proteins) interactions regulate multiple phases of epithelial polarization by providing cell-intrinsic signals that are required for single lumen formation.

  3. It is postulated that ZO-1, when not phosphorylated by PKC (show PRRT2 Proteins), keeps Octn2 (show SLC22A5 Proteins) in an active state, while elimination of this binding in DeltaPDZ mutant or after ZO-1 phosphorylation leads to diminution of Octn2 (show SLC22A5 Proteins) activity.

  4. Results uncovered ZO-1 as part of a signaling node activated by VEGF (show VEGFA Proteins), but not Ang-1 (show ANGPT1 Proteins), that specifically modulates endothelial cells proliferation during angiogenesis.

  5. Data suggest that long noncoding RNA PlncRNA1 and microRNA miR (show MLXIP Proteins)-34c bound together to regulate the expressions of MAZ (show MAZ Proteins), ZO-1 and occludin (show OCLN Proteins).

  6. STAT3 activation downregulates the ZO-1 and occludin levels and increases the endothelial permeability through the induction of VEGF production in retinal endothelial cells.

  7. Data show that tight junction protein 1 (TJP1) suppressed expression of the catalytically proteasome subunits LMP7 (show PSMB8 Proteins) and LMP2 (show PSMB9 Proteins), decreased proteasome activity, and enhanced proteasome inhibitor sensitivity in vitro and in vivo through suppression of EGFR (show EGFR Proteins)/JAK1 (show JAK1 Proteins)/STAT3 (show STAT3 Proteins) signaling.

  8. ZO-1 highly expresses in cell-cell junctions and is related to odontoblast differentiation, which may contribute to dental pulp repair or even the formation of an odontoblast layer.

  9. this study shows that the expression and the immunoreactivity of ZO-1 is decreased in the nasal epithelium of patients with allergic rhinitis

  10. The frequency of alleles and genotypes of rs2291166 gene polymorphism TJP1 was determined in the Mexico Mestizos population. The ancestral allele was the most prevalent. The conformational effect of this amino acid change was performed in silico.

Mouse (Murine) Tight Junction Protein 1 (Zona Occludens 1) (TJP1) interaction partners

  1. STAT3 activation downregulates the ZO-1 and occludin levels and increases the endothelial permeability through the induction of VEGF production in retinal endothelial cells.

  2. Cx43 (show GJA1 Proteins) tethers the F-actin cytoskeleton through a ZO-1 linker and supports cell spreading and exploration during locomotion in cerebral endothelial cells.

  3. Expression of Podocalyxin (show PODXL Proteins), which positively regulates the formation of microvilli and the apical membrane, is repressed in embryoid bodies lacking both ZO-1 and ZO-2 (show TJP2 Proteins) and this correlates with an aberrant submembranous localization of Ezrin (show EZR Proteins).

  4. Zonula occludens-1, occludin (show OCLN Proteins) and E-cadherin (show CDH1 Proteins) expression and organization in salivary glands

  5. Tjp1 expression was decreased in glomerular diseases in human and animal models, our results indicate that the suppression of Tjp1 could directly aggravate glomerular disorders, highlights Tjp1 as a potential therapeutic target.

  6. Arecoline increases the production of TNF-alpha (show TNF Proteins) and induces protein redistribution of ZO-1.

  7. Vcl (show VCL Proteins) plays a crucial role in stabilizing gap junctions and myocyte integrity through direct interactions with ZO-1 and stabilization of CX43 (show GJA1 Proteins).

  8. Activation of RhoA (show RHOA Proteins)/ROCK1 (show ROCK1 Proteins) by high glucose in diabetic nephropathy disrupts the expression and translocation of occludin (show OCLN Proteins)/ZO-1, which can be corrected by simvastatin.

  9. Vascular endothelial tight junctions and barrier function are disrupted by 15(S)-hydroxyeicosatetraenoic acid partly via protein kinase C epsilon (show PRKCE Proteins)-mediated zona occludens-1 phosphorylation at threonine 770/772.

  10. The JAM-A (show F11R Proteins) and ZO-1 genes were highly expressed in all the tested tissues.

Cow (Bovine) Tight Junction Protein 1 (Zona Occludens 1) (TJP1) interaction partners

  1. cyclic strain modulates both the expression and phosphorylation state of occludin (show OCLN Proteins) and ZO-1 in vascular endothelial cells, with putative consequences for endothelial tight junction assembly and barrier integrity

Pig (Porcine) Tight Junction Protein 1 (Zona Occludens 1) (TJP1) interaction partners

  1. ZO-1 and occludin (show OCLN Proteins) are expressed in oocytes and preimplantation embryos, and that ZO-1alpha+ is transcribed by zygotic gene activation and translated from early blastocysts with prominent increase of occludin (show OCLN Proteins) at the blastocyst stage.

TJP1 Protein Profile

Protein Summary

This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with TJP1

  • tight junction protein 1 (TJP1)
  • tight junction protein 1 (Tjp1)
  • tight junction protein 1 (ZO1)
  • tight junction protein 1 (zona occludens 1) (TJP1)
  • zonula occludens 1 (ZO1)
  • ZO-1 protein
  • zo1 protein

Protein level used designations for TJP1

tight junction protein ZO-1 , zona occludens 1 , zona occludens protein 1 , zonula occludens 1 protein , zonula occludens protein 1 , tight junction protein 1 (zona occludens 1) , zonula occludens 1

GENE ID SPECIES
7082 Homo sapiens
21872 Mus musculus
292994 Rattus norvegicus
100346390 Oryctolagus cuniculus
100718142 Cavia porcellus
407102 Bos taurus
443200 Ovis aries
101082238 Felis catus
403752 Canis lupus familiaris
415388 Gallus gallus
396567 Sus scrofa
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