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Browse our anti-ALOXE3 (ALOXE3) Antibodies

Full name:
anti-Arachidonate Lipoxygenase 3 Antibodies (ALOXE3)
On www.antibodies-online.com are 54 Arachidonate Lipoxygenase 3 (ALOXE3) Antibodies from 14 different suppliers available. Additionally we are shipping ALOXE3 Kits (10) and ALOXE3 Proteins (4) and many more products for this protein. A total of 72 ALOXE3 products are currently listed.
Synonyms:
ALOX15B, ARCI3, E-LOX, e-LOX-3, eLOX3
list all antibodies Gene Name GeneID UniProt
ALOXE3 59344 Q9BYJ1
ALOXE3 23801 Q9WV07
ALOXE3 287424  

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anti-Human ALOXE3 Antibodies:

anti-Mouse (Murine) ALOXE3 Antibodies:

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Top referenced anti-ALOXE3 Antibodies

  1. Human Polyclonal ALOXE3 Primary Antibody for EIA, WB - ABIN950356 : Han, Lan, Park, Lee, Park, Ahn, Shin, Kang, Koo, Seo, Choi, Ahn, Chanock, Kim, Rothman, Kang: Polymorphisms in innate immunity genes and risk of childhood leukemia. in Human immunology 2010 (PubMed)
    Show all 4 references for ABIN950356

  2. Human Polyclonal ALOXE3 Primary Antibody for IHC (p), IHC - ABIN442499 : Sasaki, Akiyama, Yanagi, Sakai, Miyamura, Sato, Shimizu: CYP4F22 is highly expressed at the site and timing of onset of keratinization during skin development. in Journal of dermatological science 2012 (PubMed)

More Antibodies against ALOXE3 Interaction Partners

Human Arachidonate Lipoxygenase 3 (ALOXE3) interaction partners

  1. In summary, we have identified three novel sequence variants, one in TGM1 (show TGM1 Antibodies) and two in ALOXE3, in three consanguineous families segregating lamellar ichthyosis (show LBR Antibodies) and congenital ichthyosiform erythroderma types of autosomal recessive congenital ichthyosis (show LBR Antibodies).

  2. Case Report: homozygous ALOXE3 mutation causing autosomal recessive congenital ichthyosis (show LBR Antibodies).

  3. Loss-of-function mutations in the LOX (show LOX Antibodies) genes ALOX12B (show ALOX12B Antibodies) and ALOXE3 have been found to represent the second most common cause of autosomal recessive congenital ichthyosis (show LBR Antibodies). [review]

  4. This review covers the background to discovery of the two key lipoxygenases (LOX (show LOX Antibodies)) involved in epidermal barrier function, 12R-LOX (show ALOX12B Antibodies) and eLOX3. [review]

  5. Autosomal recessive congenital ichthyosis (show LBR Antibodies) patients with NIPAL4 (show NIPAL4 Antibodies) mutations and abnormal ichthyin (show NIPAL4 Antibodies) expression showed increased 12R-LOX (show ALOX12B Antibodies) and eLOX-3 staining and a colocalization signal of these LOXs that was three times the normal intensity.

  6. On the role of molecular oxygen in lipoxygenase activation: comparison and contrast of epidermal lipoxygenase-3 with soybean lipoxygenase-1.

  7. Dioxygenase activity of epidermal lipoxygenase-3 unveiled: typical and atypical features of its catalytic activity with natural and synthetic polyunsaturated fatty acids.

  8. ALOX12B (show ALOX12B Antibodies) mutations are the leading cause of self-improving collodion ichthyosis (show LBR Antibodies) in Scandinavia, followed by ALOXE3 mutations, and TGM1 (show TGM1 Antibodies) mutations

  9. Lipoxygenase-3 (ALOXE3) and 12(R)-lipoxygenase (ALOX12B (show ALOX12B Antibodies)) are mutated in non-bullous congenital ichthyosiform erythroderma (NCIE) linked to chromosome 17p13.1.

  10. eLOX-3 hydrolase functions in the normal process of skin differentiation, and that the loss of function mutations are the basis of the LOX (show LOX Antibodies)-dependent form of Non-bullous congenital ichthyosiform erythroderma.

Mouse (Murine) Arachidonate Lipoxygenase 3 (ALOXE3) interaction partners

  1. Loss-of-function mutations in the LOX (show LOX Antibodies) genes ALOX12B (show ALOX12B Antibodies) and ALOXE3 have been found to represent the second most common cause of autosomal recessive congenital ichthyosis (show LBR Antibodies). [review]

  2. Aloxe3 deficiency in mice resulted in early postnatal death. Skin lipid analysis demonstrated that the severity of barrier failure is related to the loss of covalently bound ceramides in both ALOX12B (show ALOX12B Antibodies)- and Aloxe3-null mice.

  3. expression of eLOX3 or addition of eLOX3 products stimulated adipogenesis under conditions that normally require an exogenous PPAR gamma (show PPARG Antibodies) ligand for differentiation

  4. The substrate preference of mouse eLOX3 and the unique occurrence of an 8S-LOX (show ALOX15B Antibodies) enzyme in mouse skin point to a potential LOX (show LOX Antibodies) pathway for the production of epoxyalcohol in murine epidermal differentiation.

  5. The 12R-LOX (show ALOX12B Antibodies)-eLOX-3 pathway plays a key role in the process of epidermal barrier acquisition by affecting lipid metabolism, as well as protein processing.

  6. findings suggest that endogenous PPARgamma (show PPARG Antibodies) ligand(s) promoting adipocyte differentiation are generated via a baicalein-sensitive pathway involving the novel eLOX-3

ALOXE3 Antigen Profile

Antigen Summary

This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with ALOXE3

  • arachidonate lipoxygenase 3 (ALOXE3) antibody
  • arachidonate lipoxygenase 3 (aloxe3) antibody
  • similar to arachidonate lipoxygenase 3 (ALOXE3) antibody
  • arachidonate lipoxygenase 3 (Aloxe3) antibody
  • arachidonate lipoxygenase 3 (LOC100342323) antibody
  • ALOX15B antibody
  • ARCI3 antibody
  • E-LOX antibody
  • e-LOX-3 antibody
  • eLOX3 antibody

Protein level used designations for ALOXE3

arachidonate lipoxygenase 3 , e-LOX-3 , epidermal lipoxygenase , epidermis-type lipoxygenase 3 , arachidonate 15-lipoxygenase, type B

GENE ID SPECIES
100062351 Equus caballus
446930 Xenopus laevis
455102 Pan troglodytes
548601 Xenopus (Silurana) tropicalis
100014706 Monodelphis domestica
59344 Homo sapiens
23801 Mus musculus
489487 Canis lupus familiaris
100511043 Sus scrofa
517001 Bos taurus
287424 Rattus norvegicus
425997 Gallus gallus
100342323 Oryctolagus cuniculus
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