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ALOXE3 Products

(Arachidonate Lipoxygenase 3 (ALOXE3))

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This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009].

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Featured ALOXE3 Categories

ALOXE3 Antibodies

High quality antibodies with extensive validation data.

ALOXE3 ELISA Kits

Reliable ELISA kits for a wide range of species.

ALOXE3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ALOXE3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7155980
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC (p), WB
Validations
  • (2)
Cat. No. ABIN2856503
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF
Validations
  • (1)
Cat. No. ABIN7264287
Quantity 200 μL
Datasheet Datasheet

Recommended ALOXE3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964997
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953909
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1568302
Quantity 96 tests
Datasheet Datasheet

Recommended ALOXE3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3137520
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093553
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344926
Quantity 2 μg
Datasheet Datasheet

Latest Publications for our ALOXE3 products

Sasaki, Akiyama, Yanagi, Sakai, Miyamura, Sato, Shimizu: "CYP4F22 is highly expressed at the site and timing of onset of keratinization during skin development." in: Journal of dermatological science, Vol. 65, Issue 2, pp. 156-8, (2012) (PubMed).

Synonyms and alternative names related to ALOXE3

arachidonate lipoxygenase 3 (ALOXE3), arachidonate lipoxygenase 3 L homeolog (aloxe3.L), arachidonate lipoxygenase 3 (aloxe3), arachidonate lipoxygenase 3 (Aloxe3), arachidonate 15-lipoxygenase, type B (ALOX15B), ALOX15B, ARCI3, e-lox, E-LOX, e-LOX-3, elox3, eLOX3

Protein level used designations for ALOXE3

  • arachidonate lipoxygenase 3
  • e-LOX-3
  • epidermal lipoxygenase
  • epidermis-type lipoxygenase 3
  • arachidonate 15-lipoxygenase, type B
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