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Browse our Integrin beta 1 Proteins (ITGB1)

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Integrin beta 1 Proteins (ITGB1)
On are 19 Integrin beta 1 (ITGB1) Proteins from 7 different suppliers available. Additionally we are shipping Integrin beta 1 Antibodies (846) and Integrin beta 1 Kits (25) and many more products for this protein. A total of 904 Integrin beta 1 products are currently listed.
4633401G24Rik, AA409975, AA960159, CD29, ENSMUSG00000051907, FNRB, Gm9863, GPIIA, itgb1, MDF2, MSK12, VLA-BETA, VLAB
list all proteins Gene Name GeneID UniProt
ITGB1 16412 P09055
ITGB1 24511 P49134
ITGB1 3688 P05556

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Integrin beta 1 Proteins (ITGB1) by Origin

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Top referenced Integrin beta 1 Proteins

  1. Human ITGB1 Protein expressed in Wheat germ - ABIN2752830 : Ahn, Mohamedali, Anand, Cheruku, Birch, Sowmya, Cantor, Ranganathan, Inglis, Frank, Agrez, Nice, Baker: Characterization of the interaction between heterodimeric ?v?6 integrin and urokinase plasminogen activator receptor (uPAR) using functional proteomics. in Journal of proteome research 2014 (PubMed)

More Proteins for Integrin beta 1 Interaction Partners

Xenopus laevis Integrin beta 1 (ITGB1) interaction partners

  1. Findings demonstrate the neurotrophin (show BDNF Proteins), BDNF (show BDNF Proteins)-dependent formation of integrin beta1-based adhesions in the growth cone and reveal how a positive regulator of substrate adhesions can block the negative remodeling and growth inhibitory effects of myelin-associated glycoprotein (show MAG Proteins) .

  2. Findings identify beta(1)-integrin as an important functional cargo during Ca(2+)-dependent rapid endocytosis stimulated by a diffusible guidance cue in Xenopus spinal neurons.

Mouse (Murine) Integrin beta 1 (ITGB1) interaction partners

  1. results demonstrate that c-Cbl (show CBL Proteins) mediates the ubiquitination/degradation of integrin beta1, which leads to COMP (show COMP Proteins) deficiency-induced dilated cardiomyopathy.

  2. Ptrh2 (show PTRH2 Proteins) levels were up-regulated in dystrophin (show DMD Proteins) deficient mdx (show DMD Proteins) muscle, which correlates with the elevated levels of the a7b1 integrin observed in mdx (show DMD Proteins) muscle and Duchenne muscular dystrophy (show DMD Proteins) patients. Similar to the a7 integrin, Ptrh2 (show PTRH2 Proteins) expression was decreased in laminin-a2 null gastrocnemius muscle

  3. this study has identified a new role for Parvin (show PARVA Proteins) and alphaPix (show ARHGEF6 Proteins) downstream of the integrin-ILK (show ILK Proteins) signaling axis for mammary epithelial cell differentiation.

  4. low expression of alpha2beta1 integrin increased protein kinase B (AKT) activation and alpha-smooth muscle actin (alpha-SMA) expression. This occurred due to the instability of phosphatase and tensin homolog (PTEN) in myofibroblasts on fibrillar collagen.

  5. By modulating its affinity with kindlin, beta3 integrin (show ITGB3 Proteins) may be able to locate near the cell edge where it can control beta1 integrin activation and clustering.

  6. These findings indicated that mechanical strain promoted osteoblastic differentiation through integrinbeta1mediated beta-catenin (show CTNNB1 Proteins) signaling.

  7. TERT (show TERT Proteins) may promote gastric cancer metastasis through the TERT (show TERT Proteins)-miR (show MLXIP Proteins)-29a-ITGB1 regulatory pathway.

  8. the rate of collagen I degradation was increased in Poldip2 (show POLDIP2 Proteins)(+/-) vs. Poldip2 (show POLDIP2 Proteins)(+/+) MASMs. Conversely, activation of the PI3K/Akt (show AKT1 Proteins)/mTOR (show FRAP1 Proteins) signaling pathway, involved in regulation of protein synthesis, was significantly elevated in Poldip2 (show POLDIP2 Proteins)(+/-) MASMs as was beta1-integrin expression.

  9. These findings show that talin and kindlin cooperatively activate integrins leading to fibronectin (show FN1 Proteins) binding and adhesion.

  10. These results suggest that Tie2 (show TEK Proteins) signaling induces alpha4beta1 integrin activation on bone marrow-mast cell progenitor for adhesion to VCAM-1 (show VCAM1 Proteins).

Human Integrin beta 1 (ITGB1) interaction partners

  1. we observed that PRL-3 regulated the clustering of integrin beta1 in FAs (show FAS Proteins) on collagen I but not on fibronectin (show FN1 Proteins). This work identifies PRL-3 as a new regulator of cell adhesion structures to the extracellular matrix, and further supports PRL-3 as a key actor of metastasis in uveal melanoma, of which molecular mechanisms are still poorly understood

  2. Study demonstrates that MARVELD1 (show MARVELD1 Proteins)-mediated balance of integrin beta1 and beta4 regulates cell surface ultrastructure and epithelial-mesenchymal transition phenotype of non-small cell lung cancer (NSCLC).

  3. Expression levels of CD98 (show SLC3A2 Proteins) and beta1-integrin-A (the activated form of beta1-integrin) were significantly increased in hepatocellular carcinoma (HCC (show FAM126A Proteins)) tissues relative to those of normal liver tissues.

  4. High expression of ITGB1 is associated with migration and invasion of nonsmall cell lung cancer.

  5. Our results suggest that an impairment in adhesion exists in vitiligo (show MITF Proteins) skin, which is supported by the diminished immunohistochemical expression of laminin, beta1 integrin, ICAM-1 (show ICAM1 Proteins) and VCAM-1 (show VCAM1 Proteins).

  6. The altered expression of anti-apoptotic gene Bcl-2 (show BCL2 Proteins) played critical roles in regulating both spontaneous and radiation-induced apoptosis in the presence of RelB (show RELB Proteins) knockdown. For the first time, we showed that RelB (show RELB Proteins) knockdown significantly attenuated the migration and invasion of DU145 prostate cancer cells, due to the reduction of integrin b-1

  7. ITGB1 role in hepatocellular carcinoma cell adhesion and motility

  8. Data show that high mobility group nucleosomal binding domain 2 (HMGN2 (show HMGN2 Proteins)) knockdown induced the increased expression of alpha5beta1 integrin on cell membranes, which resulted in a significant increase in Klebsiella pneumoniae internalization.

  9. ectopic expression of miR-17 in ovarian cancer cells resulted in repressed ILK (show ILK Proteins) phosphorylation as well as decreased production of active matrix metalloproteinase-2 (MMP-2 (show MMP2 Proteins)). Our results indicated that miR-17 hampered ovarian cancer peritoneal propagation by targeting integrin a5 and b1.

  10. results provide insight into the regulation of beta1 integrin through miR (show MLXIP Proteins)-199a-5p-mediated Ets-1 (show ETS1 Proteins) silence and will help in designing new therapeutic strategies to inhibit signal pathways induced by miR (show MLXIP Proteins)-199a-5p in breast cancer invasion

Pig (Porcine) Integrin beta 1 (ITGB1) interaction partners

  1. beta1-integrin antigen-antibody interactions and the distribution of beta1-integrin protein on spermatogonial stem cell membrane were demonstrated using atomic force microscopy

Cow (Bovine) Integrin beta 1 (ITGB1) interaction partners

  1. The overall findings suggest that the secreted galectin-3 (show LGALS3 Proteins) stimulated by PGF (show PGF Proteins) plays a role in structural luteolysis by binding to beta 1 integrin.

  2. Putative function of fibronectin (show FN1 Proteins) and its receptor (integrin alpha(5 (show ITGA5 Proteins))beta(1)) in male and female gametes during bovine fertilization in vitro.

  3. integrin activation with shear stress results in SFK-regulated caveolin-1 phosphorylation that, in turn, mediates Csk association at integrin sites, where it plays a role in downstream, shear-stimulated myosin light chain diphosphorylation.

  4. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

  5. both the gpIb-VWF (show VWF Proteins) interaction and the integrin alpha(2 (show ITGA2 Proteins))beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (show GSTA3 Proteins))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF (show VWF Proteins) is bound

  6. TRPV4 (show TRPV4 Proteins) channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling.

Integrin beta 1 (ITGB1) Protein Profile

Protein Summary

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

Alternative names and synonyms associated with Integrin beta 1 (ITGB1)

  • integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (itgb1-b)
  • integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (ITGB1)
  • integrin beta 1 (fibronectin receptor beta) (Itgb1)
  • integrin, beta 1 (Itgb1)
  • 4633401G24Rik protein
  • AA409975 protein
  • AA960159 protein
  • CD29 protein
  • ENSMUSG00000051907 protein
  • FNRB protein
  • Gm9863 protein
  • GPIIA protein
  • itgb1 protein
  • MDF2 protein
  • MSK12 protein
  • VLA-BETA protein
  • VLAB protein

Protein level used designations for Integrin beta 1 Proteins (ITGB1)

integrin beta 1 , integrin beta-1* , integrin beta-1-B , VLA-4 subunit beta , fibronectin receptor subunit beta , integrin beta-1 , beta OL , beta oligodendroglia , integrin VLA-4 subunit beta , integrin beta 1 (fibronectin receptor beta) , glycoprotein IIa , integrin VLA-4 beta subunit , very late activation protein, beta polypeptide , integrin beta-1 subunit , CSAT antigen , JG22 antigen , RGD-receptor , Fibronectin receptor subunit beta , Integrin VLA-4 subunit beta , Integrin subunit beta-1

399443 Xenopus laevis
574312 Macaca mulatta
100055024 Equus caballus
16412 Mus musculus
24511 Rattus norvegicus
3688 Homo sapiens
397019 Sus scrofa
751821 Felis catus
374058 Gallus gallus
477956 Canis lupus familiaris
281876 Bos taurus
443141 Ovis aries
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