Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Human ITGB1 Protein expressed in Wheat germ - ABIN2752830
Ahn, Mohamedali, Anand, Cheruku, Birch, Sowmya, Cantor, Ranganathan, Inglis, Frank, Agrez, Nice, Baker: Characterization of the interaction between heterodimeric ?v?6 integrin and urokinase plasminogen activator receptor (uPAR) using functional proteomics. in Journal of proteome research 2014
Findings demonstrate the neurotrophin (show BDNF Proteins), BDNF (show BDNF Proteins)-dependent formation of integrin beta1-based adhesions in the growth cone and reveal how a positive regulator of substrate adhesions can block the negative remodeling and growth inhibitory effects of myelin-associated glycoprotein (show MAG Proteins) .
Findings identify beta(1)-integrin as an important functional cargo during Ca(2+)-dependent rapid endocytosis stimulated by a diffusible guidance cue in Xenopus spinal neurons.
Itgb1 inhibition alleviates the chronic hyperproliferative dermatitis phenotype of Sharpin-deficient mice.
Taken together, acid-induced acute lung injury results in epithelial microvesicle shuttling of miR-17/221 that in turn modulates macrophage beta1 integrin recycling, promoting macrophage recruitment and ultimately contributing to lung inflammation.
Type I collagen was highly expressed in the spinal cord during the scar-forming phase and induced astrocytic scar formation via the integrin-N-cadherin (show CDH2 Proteins) pathway.
the transcription regulators YAP (show YAP1 Proteins) and TAZ (show TAZ Proteins) localise to the nucleus in the basal layer of skin and are elevated upon wound healing.
Itgb1 is an essential niche molecule that maintains satellite cell (SC) homeostasis, and sustains the expansion and self-renewal of this stem cell pool during regeneration. We further show that Itgb1 cooperates with fibroblast growth factor 2 (Fgf2 (show FGF2 Proteins)), a potent growth factor for SCs (show TWIST1 Proteins), to synergistically activate their common downstream effectors, the mitogen-activated protein (MAP) kinase Erk (show MAPK1 Proteins) and protein kinase B (Akt (show AKT1 Proteins)).
this study shows that alpha4beta1 integrin mediates memory CD8 (show CD8A Proteins)+ T cells accumulation in salivary glands after infection with lymphocytic choriomeningitis virus
FAK sustained the active integrin conformation by maintaining talin association with Rab11 endosomes in a type I phosphatidylinositol phosphate kinase (PIPKIgamma)-dependent manner.
results demonstrate that c-Cbl (show CBL Proteins) mediates the ubiquitination/degradation of integrin beta1, which leads to COMP (show COMP Proteins) deficiency-induced dilated cardiomyopathy.
Ptrh2 (show PTRH2 Proteins) levels were up-regulated in dystrophin (show DMD Proteins) deficient mdx (show DMD Proteins) muscle, which correlates with the elevated levels of the a7b1 integrin observed in mdx (show DMD Proteins) muscle and Duchenne muscular dystrophy (show DMD Proteins) patients. Similar to the a7 integrin, Ptrh2 (show PTRH2 Proteins) expression was decreased in laminin-a2 null gastrocnemius muscle
this study has identified a new role for Parvin (show PARVA Proteins) and alphaPix (show ARHGEF6 Proteins) downstream of the integrin-ILK (show ILK Proteins) signaling axis for mammary epithelial cell differentiation.
alpha5beta1 integrin can stimulate drug resistance in cancer cells via a mechanism based on inhibition of protein kinase (show CDK7 Proteins) Erk (show EPHB2 Proteins).
We measured the effect of recombinant Gal-3 (show LGALS3 Proteins) added exogenously on the lateral mobility of the alpha5b1 integrin on HeLa cells. Using single-particle tracking (SPT (show AGXT Proteins)) we detected increased lateral mobility of the integrin in the presence of Gal-3 (show LGALS3 Proteins), while its truncated C-terminal domain (Gal (show GAL Proteins)-3C) showed only minor reductions in lateral mobility.
By directly binding to the 3'UTRs of ITGA6 (show ITGA6 Proteins) and ITGB1, we found miR (show MLXIP Proteins)-30e-5p to suppress mainly the adhesion of ITGA6 (show ITGA6 Proteins) in CRC (show CALR Proteins) cells to laminin.Taken together, miR (show MLXIP Proteins)-30e-5p is a novel effector of P53 (show TP53 Proteins)-induced suppression of migration, invasion and metastasis
These data outline a new signaling mechanism by which KCa1.1 (show KCNMA1 Proteins) regulates beta1-integrin function and therefore invasiveness of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs).
sp(2) -Iminosugar alpha-glucosidase (show AGLU Proteins) inhibitor 1 (show PPP1R1A Proteins)-C-octyl-2-oxa-3-oxocastanospermine inhibits breast cancer cell migration via beta1-integrin, Stim1 (show STIM1 Proteins), and FAK (show PTK2 Proteins) signaling pathways.
beta1-integrin expression is regulated in pancreatic and colon cancer cells by the pro-oncogenic orphan nuclear receptor 4A1
The SALL4 (show SALL4 Proteins) - integrin alpha6 - integrin beta1 network promotes cell migration for metastasis via activation of focal adhesion dynamics in basal-like breast cancer cells.
membrane-proximal N-glycosylation is critical for intermolecular interactions between integrin beta1 and other cell membrane proteins, such as syndecan-4 (show SDC4 Proteins) and epidermal growth factor receptor (show EGFR Proteins). Moreover, alpha2,6-sialylation is required for beta1 activation
High ITGB1 expression is associated with lung metastasis in ovarian cancer.
the loss of MUC16 (show MUC16 Proteins) and E-cadherin (show CDH1 Proteins) expression resulted in the formation of more compact spheroids. In addition, our data describe an unusual link between E-cadherin (show CDH1 Proteins) expression and less compact spheroids. Our data also emphasize the role of MUC16 (show MUC16 Proteins) and b1 integrin in Epithelial ovarian cancer (EOC) spheroid formation.
beta1-integrin antigen-antibody interactions and the distribution of beta1-integrin protein on spermatogonial stem cell membrane were demonstrated using atomic force microscopy
The overall findings suggest that the secreted galectin-3 (show LGALS3 Proteins) stimulated by PGF (show PGF Proteins) plays a role in structural luteolysis by binding to beta 1 integrin.
Putative function of fibronectin (show FN1 Proteins) and its receptor (integrin alpha(5 (show ITGA5 Proteins))beta(1)) in male and female gametes during bovine fertilization in vitro.
integrin activation with shear stress results in SFK-regulated caveolin-1 phosphorylation that, in turn, mediates Csk association at integrin sites, where it plays a role in downstream, shear-stimulated myosin light chain diphosphorylation.
Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.
both the gpIb-VWF (show VWF Proteins) interaction and the integrin alpha(2 (show ITGA2 Proteins))beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (show GSTA3 Proteins))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF (show VWF Proteins) is bound
TRPV4 (show TRPV4 Proteins) channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling.
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
integrin beta 1
, integrin beta-1*
, integrin beta-1-B
, VLA-4 subunit beta
, fibronectin receptor subunit beta
, integrin beta-1
, beta OL
, beta oligodendroglia
, integrin VLA-4 subunit beta
, integrin beta 1 (fibronectin receptor beta)
, glycoprotein IIa
, integrin VLA-4 beta subunit
, very late activation protein, beta polypeptide
, integrin beta-1 subunit
, CSAT antigen
, JG22 antigen
, Fibronectin receptor subunit beta
, Integrin VLA-4 subunit beta
, Integrin subunit beta-1