ITGB1 Protein (His tag)

Catalog No. ABIN7319758

Product Details

Target: ITGB1 (Integrin beta 1 (ITGB1))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This ITGB1 protein is labelled with His tag.

Purpose: Recombinant Human Integrin Beta-1/ITGB1 (C-6His)

Sequence: Gln21-Asp728

Characteristics: Recombinant Human Integrin β-1/ITGB1 is produced by our Mammalian expression system and the target gene encoding Gln21-Asp728 is expressed with a 6His tag at the C-terminus.

Purity: >90 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: ITGB1 (Integrin beta 1 (ITGB1))

Alternative Name: Integrin Beta-1/ITGB1 (ITGB1 Products)

Synonyms: CD29 Protein, FNRB Protein, GPIIA Protein, MDF2 Protein, MSK12 Protein, VLA-BETA Protein, VLAB Protein, 4633401G24Rik Protein, AA409975 Protein, AA960159 Protein, ENSMUSG00000051907 Protein, Fnrb Protein, Gm9863 Protein, gpIIa Protein, cd29 Protein, fnrb Protein, gpiia Protein, itgb1 Protein, mdf2 Protein, msk12 Protein, vla-beta Protein, vlab Protein, itgb1-a Protein, itgb1-b Protein, integrin subunit beta 1 Protein, integrin beta 1 (fibronectin receptor beta) Protein, integrin subunit beta 1 S homeolog Protein, integrin beta 1 Protein, integrin subunit beta 1 L homeolog Protein, ITGB1 Protein, Itgb1 Protein, itgb1.S Protein, LOC100009173 Protein, itgb1.L Protein

Background:

Background: Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin.

Synonym: Integrin Beta-1, Fibronectin Receptor Subunit Beta, VLA-4 Subunit Beta, CD29, ITGB1, FNRB, MDF2, MSK12

Molecular Weight: 79.4 kDa

UniProt: P05556

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome