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Browse our anti-SKP1 (SKP1) Antibodies

Full name:
anti-S-Phase Kinase-Associated Protein 1 Antibodies (SKP1)
On www.antibodies-online.com are 112 S-Phase Kinase-Associated Protein 1 (SKP1) Antibodies from 18 different suppliers available. Additionally we are shipping SKP1 Proteins (22) and SKP1 Kits (14) and many more products for this protein. A total of 155 SKP1 products are currently listed.
Synonyms:
15kDa, 2610043E24Rik, 2610206H23Rik, ARABIDOPSIS SKP1 HOMOLOGUE 1, ASK1, ATSKP1, EMC19, ocp-2, OCP-II, OCP2, p19A, p19Skp1, SKP1, Skp1a, S phase kinase-associated protein 1, T4O12.17, T4O12_17, Tceb1l, UFO INTERACTING PROTEIN 1, UIP1, zgc:73186

Most Popular Reactivities for anti-SKP1 (SKP1) Antibodies

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anti-Human SKP1 Antibodies:

anti-Rat (Rattus) SKP1 Antibodies:

anti-Mouse (Murine) SKP1 Antibodies:

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Top referenced anti-SKP1 Antibodies

  1. Human Polyclonal SKP1 Primary Antibody for EIA, IP - ABIN117959 : Wang, He, Wang, Wang, Zhai, Zhou, Zhang, Zhai, Feng, Han: [Impact of Donor KIR2DS5 Genotype on Outcome Following Haploidentical Hematopoietic Stem Cell Transplantation.] in Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology 2008 (PubMed)
    Show all 13 references for ABIN117959

  2. Human Polyclonal SKP1 Primary Antibody for EIA, WB - ABIN357264 : Wu, Xu, Schulman, Jeffrey, Harper, Pavletich: Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase. in Molecular cell 2003 (PubMed)
    Show all 5 references for ABIN357264

  3. Human Monoclonal SKP1 Primary Antibody for IF, WB - ABIN393543 : Davies, Kaplan: Hsp90-Sgt1 and Skp1 target human Mis12 complexes to ensure efficient formation of kinetochore-microtubule binding sites. in The Journal of cell biology 2010 (PubMed)
    Show all 5 references for ABIN393543

  4. Chicken Monoclonal SKP1 Primary Antibody for BI, IP - ABIN968019 : Carrano, Pagano: Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression. in The Journal of cell biology 2001 (PubMed)
    Show all 4 references for ABIN968019

  5. Human Polyclonal SKP1 Primary Antibody for IP, WB - ABIN233777 : Shiraishi, Zhou, Aoki, Sato, Chiba, Tanaka, Yoshida, Nabeshima, Nabeshima, Tamura: TBP-interacting protein 120B (TIP120B)/cullin-associated and neddylation-dissociated 2 (CAND2) inhibits SCF-dependent ubiquitination of myogenin and accelerates myogenic differentiation. in The Journal of biological chemistry 2007 (PubMed)

  6. Human Monoclonal SKP1 Primary Antibody for ICC, FACS - ABIN969397 : Werden, Lanchbury, Shattuck, Neff, Dufford, McFadden: The myxoma virus m-t5 ankyrin repeat host range protein is a novel adaptor that coordinately links the cellular signaling pathways mediated by Akt and Skp1 in virus-infected cells. in Journal of virology 2009 (PubMed)

  7. Human Monoclonal SKP1 Primary Antibody for FACS, IHC - ABIN969398 : Plesca, Mazumder, Gama, Matsuyama, Almasan: A C-terminal fragment of Cyclin E, generated by caspase-mediated cleavage, is degraded in the absence of a recognizable phosphodegron. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against SKP1 Interaction Partners

Human S-Phase Kinase-Associated Protein 1 (SKP1) interaction partners

  1. Both the F-box domain of Skp2 and Skp1-Skp2 domain motions displaying preferential conformational control can together facilitate polyubiquitination of a wide variety of substrates.

  2. Skp1 is critical to lung cancer pathogenesis

  3. Data show that epithelial-mesenchymal transition (EMT (show ITK Antibodies))-transcription factors can be dynamically degraded by an atypical ubiquitin E3 ligase complex Skp1-Pam (show PAM Antibodies)-Fbxo45 (show FBXO45 Antibodies) (SPFFbxo45).

  4. We discuss how these results can explain the rapid association of Cdc34 (show CDC34 Antibodies) and Skp1-cullin-F-box ligase (SCF (show KITLG Antibodies)).

  5. SKP1 variation modifies association between Parkinson's disease and ubiquitin-proteasome system-inhibiting pesticides

  6. Studies indicate that in SCFs, Rbx1 serves as the RING-containing enzyme, Cul1 (show CUL1 Antibodies) is the Cullin scaffold, and Skp1 is an adaptor, which serves to link the beta-TrCP (show BTRC Antibodies) F-box substrate-specific factor to the rest of the ligase.

  7. Substrate binding promotes formation of the Skp1-Cul1 (show CUL1 Antibodies)-Fbxl3 (show FBXL3 Antibodies) (SCF (show KITLG Antibodies)(Fbxl3 (show FBXL3 Antibodies))) protein complex.

  8. Skp1-Cul1 (show CUL1 Antibodies)-F-box ubiquitin ligase (SCF (show KITLG Antibodies)(betaTrCP (show BTRC Antibodies)))-mediated destruction of the ubiquitin-specific protease USP37 (show USP37 Antibodies) during G2-phase promotes mitotic entry

  9. Deconjugation of Nedd8 (show NEDD8 Antibodies) from Cul1 (show CUL1 Antibodies) is directly regulated by Skp1-F-box and substrate, and the COP9 (show COPS8 Antibodies) signalosome inhibits deneddylated SCF (show KITLG Antibodies) by a noncatalytic mechanism.

  10. we determined that the phage-encoded GogB effector protein in Salmonella targets the host SCF (show KITLG Antibodies) E3 type ubiquitin ligase through an interaction with Skp1 and the human F-box only 22 (FBXO22 (show FBXO22 Antibodies)) protein

Cow (Bovine) S-Phase Kinase-Associated Protein 1 (SKP1) interaction partners

  1. The SCF (show KITLG Antibodies)-complex gene expression has been characterized during bovine preimplantation development (show MTA2 Antibodies).

Arabidopsis thaliana S-Phase Kinase-Associated Protein 1 (SKP1) interaction partners

  1. ABA induced the phosphorylation of three basic helix-loop-helix (bHLH) transcription factors, called AKSs (ABA-responsive kinase substrates; AKS1, AKS2, and AKS3), in Arabidopsis guard cells

  2. ASK1 and ASK2, are required for Agrobacterium-mediated plant transformation.

  3. ASK1 or ASK2 overexpression could rescue or partially rescue the Abscisic acid (ABA)insensitivity of abi5 (show ABI5 Antibodies)-1 mutants, respectively.

  4. ASK1 is predominately expressed from leptotene to pachytene, and negatively regulates recombination in Arabidopsis.

  5. Through the ASK1-mediated proteolysis pathway, ASK1 proteins showed pleiotropic functions including photomorphogenesis, circadian oscillation, post-translation process, stress-responses and cell expansion or elongation.

  6. ASK1 is required for normal SYN1 distribution during meiotic prophase I and suggest that ask1 associated defects may be primarily related to SYN1 mislocalization.

  7. These results raise the interesting possibility that ASK1 controls chromatin structure by targeting of either an early regulator of meiotic progression or possibly matrix attachment proteins for destruction.

Mouse (Murine) S-Phase Kinase-Associated Protein 1 (SKP1) interaction partners

  1. Substrate binding promotes formation of the Skp1-Cul1 (show CUL1 Antibodies)-Fbxl3 (show FBXL3 Antibodies) (SCF (show KITLG Antibodies)(Fbxl3 (show FBXL3 Antibodies))) protein complex.

  2. In this review, deficiency of SKP1A in SN4741 cells closely recapitulates cardinal (show CARD8 Antibodies) features of the dopamine (DA) neuron pathology of human Parkinson's disease, such as decreased expression of DA phenotypic markers and cell cycle aberrations.

  3. phosphorylated NIPA (show ZC3HC1 Antibodies) is degraded in late mitosis in an APC (show APC Antibodies)/C(Cdh1 (show CDH1 Antibodies))-dependent manner

  4. Skp1 is a potential modifier in sporadic Parkinson disease neurodegeneration

Guinea Pig S-Phase Kinase-Associated Protein 1 (SKP1) interaction partners

  1. study evaluated the conformational stabilities of OCP1 (show FBXO2 Antibodies) and OCP2

SKP1 Antigen Profile

Antigen Summary

This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

Alternative names and synonyms associated with SKP1

  • S-phase kinase-associated protein 1 (skp1) antibody
  • S-phase kinase-associated protein 1 (SKP1) antibody
  • S-phase kinase-associated protein 1 (LOC100340043) antibody
  • S-phase kinase-associated protein 1 (Skp1) antibody
  • S-phase kinase-associated protein 1A (Skp1a) antibody
  • S-phase kinase-associated protein 1A (Skp1) antibody
  • 15kDa antibody
  • 2610043E24Rik antibody
  • 2610206H23Rik antibody
  • ARABIDOPSIS SKP1 HOMOLOGUE 1 antibody
  • ASK1 antibody
  • ATSKP1 antibody
  • EMC19 antibody
  • ocp-2 antibody
  • OCP-II antibody
  • OCP2 antibody
  • p19A antibody
  • p19Skp1 antibody
  • SKP1 antibody
  • Skp1a antibody
  • S phase kinase-associated protein 1 antibody
  • T4O12.17 antibody
  • T4O12_17 antibody
  • Tceb1l antibody
  • UFO INTERACTING PROTEIN 1 antibody
  • UIP1 antibody
  • zgc:73186 antibody

Protein level used designations for SKP1

S-phase kinase-associated protein 1 , SCF complex component , S-phase kinase-associated protein 1A , S-phase kinase-associated protein 1A (p19A) , OCP-2 , RNA polymerase II elongation factor-like protein OCP2 , SIII , cyclin A/CDK2-associated p19 , cyclin A/CDK2-associated protein p19 , cyclin-A/CDK2-associated protein p19 , organ of Corti protein 2 , organ of Corti protein II , p19skp1 , transcription elongation factor B , p19A

GENE ID SPECIES
100195936 Salmo salar
100240716 Ovis aries
100340043 Oryctolagus cuniculus
100528639 Ictalurus punctatus
393716 Danio rerio
462063 Pan troglodytes
474682 Canis lupus familiaris
549273 Xenopus (Silurana) tropicalis
735335 Pan troglodytes
6500 Homo sapiens
287280 Rattus norvegicus
615427 Bos taurus
416319 Gallus gallus
100174716 Pongo abelii
380538 Xenopus laevis
843928 Arabidopsis thaliana
21402 Mus musculus
100135616 Cavia porcellus
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