Browse our anti-HAP1 (HAP1) Antibodies

Full name:
anti-Huntingtin Associated Protein 1 Antibodies (HAP1)
On are 87 Huntingtin Associated Protein 1 (HAP1) Antibodies from 18 different suppliers available. Additionally we are shipping HAP1 Proteins (6) and HAP1 Kits (4) and many more products for this protein. A total of 103 HAP1 products are currently listed.
APE, Apex, HAP-1, HAP1, HAP1-A, HAP1-B, HAP2, hHLP1, HIP5, HLP, Ref-1

Most Popular Reactivities for anti-HAP1 (HAP1) Antibodies

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anti-Mouse (Murine) HAP1 Antibodies:

anti-Human HAP1 Antibodies:

anti-Rat (Rattus) HAP1 Antibodies:

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Top referenced anti-HAP1 Antibodies

  1. Human Monoclonal HAP1 Primary Antibody for ICC, FACS - ABIN259097 : Chan, Nasir, Gutekunst, Coleman, Maclean, Maas, Metzler, Gertsenstein, Ross, Nagy, Hayden: Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior. in Human molecular genetics 2002 (PubMed)
    Show all 7 references for 259097

  2. Mouse (Murine) Monoclonal HAP1 Primary Antibody for IF, WB - ABIN968461 : Gutekunst, Li, Yi, Ferrante, Li, Hersch: The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): comparison with huntingtin in rat and human. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1998 (PubMed)
    Show all 5 references for 968461

  3. Mouse (Murine) Polyclonal HAP1 Primary Antibody for EIA, WB - ABIN615992 : Rong, McGuire, Fang, Sheng, Shin, Li, Li: Regulation of intracellular trafficking of huntingtin-associated protein-1 is critical for TrkA protein levels and neurite outgrowth. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 2 references for 615992

  4. Human Polyclonal HAP1 Primary Antibody for ELISA, WB - ABIN188689 : Takeshita, Fujinaga, Zhao, Yanai, Shinoda: Huntingtin-associated protein 1 (HAP1) interacts with androgen receptor (AR) and suppresses SBMA-mutant-AR-induced apoptosis. in Human molecular genetics 2006 (PubMed)

More Antibodies against HAP1 Interaction Partners

Mouse (Murine) Huntingtin Associated Protein 1 (HAP1) interaction partners

  1. findings provide evidence that endogenous APE1 (show APEX1 Antibodies) protects against ischemic infarction in both gray and white matter and facilitates the functional recovery of the central nervous system after mild stroke injury

  2. HAP1 co-localizes with synapsin I (show SYN1 Antibodies) in cortical neurons as discrete puncta

  3. Suppression of Ape1/Ref-1 (show APEX1 Antibodies) redox function leads to an increased cell surface retention of IL-12 (show IL12A Antibodies) and enhances Th1 (show HAND1 Antibodies) responses.

  4. findings suggest that Hap1 is important for insulin (show INS Antibodies) secretion of pancreatic beta-cells via regulating the intracellular trafficking and plasma membrane localization of Cav1.2 (show CACNA1C Antibodies), providing new insight into the mechanisms that regulate insulin (show INS Antibodies) release from pancreatic beta-cells.

  5. Is closely associated with upregulation of the Ref1 (show THOC4 Antibodies)/Nrf2 (show NFE2L2 Antibodies) signalling pathway.

  6. Results show the stimulatory effect of PARP-1 (show PARP1 Antibodies) on APE1 (show APEX1 Antibodies)-dependent base excision repair (BER). PARP-1 (show PARP1 Antibodies) and APE1 (show APEX1 Antibodies) appear to have a functional interaction in BER since PARP-1 (show PARP1 Antibodies) can stimulate the strand incision activity of APE1 (show APEX1 Antibodies).

  7. Early loss of Hap1 significantly reduces postnatal hippocampal neurogenesis, and leads to adult depressive-like behavior.

  8. Hap1 interacts with Bcr (show BCR Antibodies) on microtubules to regulate neuronal differentiation.

  9. increases in APEX1 (show APEX1 Antibodies) level confer protection against the murine paternal age effect, thus highlighting the role of APEX1 (show APEX1 Antibodies) in preserving reproductive health with increasing age and in protection against genotoxin-induced mutagenesis in somatic cells

  10. Endothelial cell tumor proliferation was found to be dependent on Apex-1 (show APEX1 Antibodies) expression.

Human Huntingtin Associated Protein 1 (HAP1) interaction partners

  1. HAP1 (show APEX1 Antibodies) is expressed in endocrine cells of the human gut (show GUSB Antibodies).

  2. data fully support that HAP1 (show APEX1 Antibodies) is a GKAP (show DLGAP1 Antibodies), anchoring specifically to the cGMP-dependent protein kinase (show CDK7 Antibodies) isoform Ibeta, and provide further evidence that also PKG (show PRKG1 Antibodies) spatiotemporal signaling is largely controlled by anchoring proteins

  3. HAP1 (show APEX1 Antibodies) gene expression is related to the radiosensitivity of breast cancer cells and may play an important role in the regulation of cellular radiosensitivity

  4. Overexpression of HAP1 (show APEX1 Antibodies) reduced in vitro cell growth in breast cancer cell lines.

  5. The results of this study found no association was found between the HAP1 (show APEX1 Antibodies) T441M polymorphism and the age at onset of Huntington's disease .

  6. The results of this study suggested that HAP1 (show APEX1 Antibodies) co-localizes and associates with APP (show APP Antibodies) in physiological conditions of mouse and human brain.

  7. WT HTT (show HTT Antibodies) regulates ciliogenesis by interacting through huntingtin-associated protein 1 (HAP1) with pericentriolar material 1 protein (PCM1 (show PCM1 Antibodies)).

  8. HAP1 (show APEX1 Antibodies)/stigmoid body interacts with the normal ataxin-3 (show ATXN3 Antibodies) through Josephin (show ATXN3 Antibodies) domain

  9. sortilin (show SORT1 Antibodies) stabilizes the proBDNF.HAP1 complex

  10. ADORA2A (show ADORA2A Antibodies), but not HAP1 (show APEX1 Antibodies) or OGG1 (show OGG1 Antibodies), may have a role in age at onset in Huntington's disease

HAP1 Antigen Profile

Antigen Summary

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alternative names and synonyms associated with HAP1

  • apurinic/apyrimidinic endonuclease 1 (Apex1) antibody
  • huntingtin-associated protein 1 (HAP1) antibody
  • huntingtin-associated protein 1 (Hap1) antibody
  • APE antibody
  • Apex antibody
  • HAP-1 antibody
  • HAP1 antibody
  • HAP1-A antibody
  • HAP1-B antibody
  • HAP2 antibody
  • hHLP1 antibody
  • HIP5 antibody
  • HLP antibody
  • Ref-1 antibody

Protein level used designations for HAP1

AP endonuclease 1 , APEN , APEX nuclease , DNA-(apurinic or apyrimidinic site) lyase , apurinic-apyrimidinic endonuclease 1 , redox factor-1 , HAP-1 , huntingtin-associated protein 2 , neuroan 1 , huntingtin-associated protein 1 (neuroan 1)

11792 Mus musculus
9001 Homo sapiens
15114 Mus musculus
29430 Rattus norvegicus
607751 Canis lupus familiaris
618422 Bos taurus
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