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anti-Human Complement Factor B antibody for Immunoprecipitation

Recommended Complement Factor B Antibody (supplied by: Log in to see )

Antigen
Complement Factor B (CFB) Antibodies
  • AHUS4
  • AI195813
  • AI255840
  • B
  • bf
  • BF
  • Bf
  • Bf-1
  • bf/c2
  • Bf B
  • bfb-A
  • BFD
  • Brre-Bf
  • C2
  • CFAB
  • CFB
  • Da1-24
  • Fb
  • FB
  • FBI12
  • fc04c04
  • GBG
  • H2-Bf
  • LOC397725
  • PBF2
  • Sp152
  • wu:fc04c04
  • zgc:114032
Reactivity
Human
168
41
37
Host
Mouse
119
56
17
7
Clonality
Monoclonal
Conjugate
This Complement Factor B antibody is un-conjugated
21
15
9
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Western Blotting (WB)
123
119
28
27
22
19
11
10
10
10
6
5
3
2
2
2
1
1
Supplier
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Catalog No. ABIN1106809
$ 412.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089556724 ABIN1106810 EIA IP WB Mouse IgG2a Log in to see P21-15 3
0.00089556724 ABIN1106808 EIA IP WB Mouse IgG1 Log in to see M13-12 1
0.00089556724 ABIN568601 ID IHC (p) IP Goat Log in to see Polyclonal
0.00089556724 ABIN457969 IP Goat IgG Log in to see Polyclonal
0.00089556724 ABIN2237070 IP ELISA WB Mouse IgG2b AA 26-764 Log in to see 7H80
0.00089556724 ABIN2619157 ID FACS IP IHC ELISA WB Goat Log in to see Polyclonal
0.00089556724 ABIN4299960 IA IP WB Mouse IgG1 Log in to see M13-12
0.00089556724 ABIN2237082 IP ELISA WB Mouse IgG1 Log in to see 13A39
0.00089556724 ABIN2237084 IP ELISA WB Mouse IgG1 Log in to see 13A40
0.00089556724 ABIN2237080 IP ELISA WB Mouse IgG2a Log in to see 13A38

Top referenced anti-Complement Factor B antibody for Immunoprecipitation

Similar anti-Complement Factor B Antibodies

Application / Reactivity Human
ELISA 105 Antibodies
Enzyme Immunoassay (EIA) 11 Antibodies
Flow Cytometry (FACS) 24 Antibodies
Functional Studies (Func) 6 Antibodies
Immunoassay (IA) 3 Antibodies
Immunocytochemistry (ICC) 4 Antibodies
Immunodiffusion (ID) 6 Antibodies
Immunoelectrophoresis (IEP) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 28 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 2 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 15 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 22 Antibodies
Immunoprecipitation (IP) 11 Antibodies
Radioimmunoassay (RIA) 2 Antibodies
Western Blotting (WB) 104 Antibodies

General

Antigen Complement Factor B (CFB) Antibodies
Reactivity Human
(168), (41), (37)
Host Mouse
(119), (56), (17), (7)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Complement Factor B antibody is un-conjugated
(21), (15), (9), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Western Blotting (WB)
(123), (119), (28), (27), (22), (19), (11), (10), (10), (10), (6), (5), (3), (2), (2), (2), (1), (1)
Pubmed 3 references available
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Product Details anti-Complement Factor B Antibody

Target Details Complement Factor B Application Details Handling References for anti-Complement Factor B Antibody (ABIN1106809) Images
Specificity This antibody recognizes human complement Factor B/Ba.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Purified
Clone M20-6
Isotype IgG1

Target Details Complement Factor B

Product Details anti-Complement Factor B Antibody Application Details Handling References for anti-Complement Factor B Antibody (ABIN1106809) Images back to top
Antigen
Alternative Name Complement Factor B (CFB Antibody Abstract)
Background Factor B is an acute-phase protein. Levels of factor B increase during inflammation. Complement factor B is a single- chain molecule of 764 amino acids (MW of 90 kD), including a leader peptide of 25 amino acids. Factor B provides the catalytic subunit of the C3/C5 convertases of the alternative complement pathway. Assembly of the C3 convertase (C3bBb) requires binding of factor B to C3b (C3.H2O) and factor D-mediated cleavage of bound factor B resulting in the release of Ba (MW 33 kD). The C3 convertase is stabilized by the binding of properdin. This provides a positive amplification loop for the classical and alternative complement pathways. Bb (MW 60 kD) is the serine protease element of this convertase. After cleavage of C3, the C5 convertase ((C3b)2Bb) is formed. The Bb fragment may be regarded as a better indicator of the alternative pathway of complement activation than Ba as impaired renal filtration does directly influence Ba levels. Whereas Bb is elevated 2.2-fold in chronic renal failure (CRF) patients, plasma concentrations of Ba are 8.4-fold higher in CRF and 16-fold higher in end-stage renal disease (ESRD) patients compared to normals.In addition to complement activation, factor B fragments participate in other immunological functions.Synonyms: BF, BFD, C3/C5 convertase, CFB, Glycine-rich beta glycoprotein, PBF2, Properdin factor B
Gene ID 629
NCBI Accession NP_001701
UniProt P00751
Research Area Coagulation
Pathways Complement System

Application Details

Product Details anti-Complement Factor B Antibody Target Details Complement Factor B Handling References for anti-Complement Factor B Antibody (ABIN1106809) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Complement Factor B Antibody Target Details Complement Factor B Application Details References for anti-Complement Factor B Antibody (ABIN1106809) Images back to top
Concentration 0.1 mg/mL
Buffer PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2 - 8 °C.

References for anti-Complement Factor B Antibody (ABIN1106809)

Product Details anti-Complement Factor B Antibody Target Details Complement Factor B Application Details Handling Images back to top
Background publications

Oppermann, Kurts, Zierz, Quentin, Weber, Götze: "Elevated plasma levels of the immunosuppressive complement fragment Ba in renal failure." in: Kidney international, Vol. 40, Issue 5, pp. 939-47, 1992

Oppermann, Baumgarten, Brandt, Gottsleben, Kurts, Götze: "Quantitation of components of the alternative pathway of complement (APC) by enzyme-linked immunosorbent assays." in: Journal of immunological methods, Vol. 133, Issue 2, pp. 181-90, 1990

Oppermann, Haubitz, Quentin, Götze: "Complement activation in patients with renal failure as detected through the quantitation of fragments of the complement proteins C3, C5, and factor B." in: Klinische Wochenschrift, Vol. 66, Issue 18, pp. 857-64, 1988