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|Antigen||Plasminogen (PLG) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This PLG antibody is un-conjugated Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-PLG AntibodyTarget Details PLG Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human PLG|
Target Details PLGProduct Details anti-PLG Antibody Application Details Handling Images back to top
|Alternative Name||Plasminogen (PLG Antibody Abstract)|
Plasminogen is a plasma protein synthesised mostly in the liver. Plasma concentration is usually in the range of 70 to 200 mg/l. Plasminogen is activated by tissue plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen.
Synonyms: Plasminogen, Angiostatin, DKFZp779M0222, Microplasmin, Plasmin, Plasmin heavy chain A, PLG, PLMN_HUMAN.
|Research Area||Proteolysis / Ubiquitin, Angiogenesis, Coagulation, Proteases|
Application DetailsProduct Details anti-PLG Antibody Target Details PLG Handling Images back to top
|Restrictions||For Research Use only|
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|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at -20°C|
|Expiry Date||12 months|
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