Browse our GNA13 Proteins (GNA13)

Full name:
Guanine Nucleotide Binding Protein (G Protein), alpha 13 Proteins (GNA13)
On www.antibodies-online.com are 3 Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13) Proteins from 2 different suppliers available. Additionally we are shipping GNA13 Antibodies (72) and many more products for this protein. A total of 78 GNA13 products are currently listed.
Synonyms:
AU024132, AU043124, fj64c01, G13, Galpha13, GNA13, wu:fe25e05, wu:fj64c01, zgc:112436
list all proteins Gene Name GeneID UniProt
Rat GNA13 GNA13 303634  
GNA13 10672 Q14344
GNA13 14674 P27601

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GNA13 Proteins (GNA13) by Origin

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More Proteins for GNA13 Interaction Partners

Zebrafish Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13) interaction partners

  1. In embryos defective for S1pr2 (show S1PR2 Proteins)/Galpha13 signaling, endocardial precursors failed to migrate towards the midline, and the presumptive endocardium surrounded the bilaterally-located myocardial cells rather than being encompassed by them.

  2. Gpr56 (show GPR56 Proteins) regulates oligodendrocyte development via interactions with Galpha12/13 and RhoA (show RHOA Proteins)

  3. S1pr2 (show S1PR2 Proteins)/Galpha13 signaling controls myocardial migration by regulating endoderm convergence.

  4. Galpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton.

Human Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13) interaction partners

  1. Findings indicate a tumor suppressive role for G protein subunit alpha 13 (Galpha13) and rhoA (show RHOA Proteins) GTP-binding protein (RhoA (show RHOA Proteins)) in Burkitt's lymphoma and diffuse large B-cell lymphoma (DLBCL).

  2. Data (including data from studies using transgenic mice) suggest that R7BP (show RGS7BP Proteins)-RGS7 heterotrimers interact with Galpha13 to augment signaling pathways in neurons that regulate neurite morphogenesis. (R7BP (show RGS7BP Proteins) = RGS7 family binding protein; RGS7 = regulator of G-protein signaling 7 protein; Galpha13 = GTP-binding protein alpha subunit (show POLG Proteins) 13)

  3. Upregulation of GNA13 expression increased the proliferation and tumorigenicity of gastric cancer.

  4. Knockdown DDR1 (show DDR1 Proteins) reversed the effects of Galpha13 knockdown on cell-cell adhesion and proteolytic invasion in three-dimensional collagen.

  5. RGS22 acts as a tumor suppressor, repressing human pancreatic adenocarcinoma cell migration by coupling to GNA12/13.

  6. Galpha13 Switch Region 2 Binds to the Talin Head Domain and Activates alphaIIbbeta3 Integrin in Human Platelets

  7. GNA13 expression in breast cancer cells is regulated by post-transcriptional mechanisms involving miR (show MLXIP Proteins)-31.

  8. Data show that N-linked glycosylation of protease-activated receptor-1 (PAR1 (show F2R Proteins)) at extracellular loop 2 (ECL2) controls G12 (show TCF3 Proteins)/13 versus Gq G-proteins coupling specificity in response to thrombin (show F2 Proteins) stimulation.

  9. Our findings highlight the important role of miR (show MLXIP Proteins)-29c in regulating CRC (show CALR Proteins) EMT (show ITK Proteins) via GSK-3b/b-catenin signaling by targeting GNA13 and PTP4A (show PTP4A2 Proteins) and provide new insights into the metastatic basis of colorectal cancer

  10. These results place Blk (show BLK Proteins) upstream of the p190RhoGAP (show GRLF1 Proteins)-RhoA (show RHOA Proteins) pathway in Galpha13-activated cells, overall representing an opposing signaling module during CXCL12 (show CXCL12 Proteins)-triggered invasion.

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13) interaction partners

  1. GNA13 loss is associated with GC B (show NPR2 Proteins)-cell persistence, in which impaired apoptosis and ongoing somatic hypermutation may lead to an increased risk of lymphoma development.

  2. Selective inhibition of G12 (show TCF3 Proteins)/13 signaling in macrophages can augment atheroprotective B-cell populations and ameliorate atherosclerosis.

  3. Gpr56 (show GPR56 Proteins) regulates oligodendrocyte development via interactions with Galpha12/13 and RhoA (show RHOA Proteins)

  4. findings identify a Galpha13-dependent pathway that exerts dual actions in suppressing growth and blocking dissemination of germinal centre B cells that is frequently disrupted in germinal centre B-cell-derived lymphoma

  5. Direct Galpha13 binding to ITGB3 (show ITGB3 Proteins) cytoplasmic domain regulates integrin outside-in signaling and thrombus formation in platelets.

  6. Galpha (show SUCLG1 Proteins) 13 is activated in sensory neurons mediated by lysophosphatidylinositol.

  7. Galpha13 binding to VE-cadherin (show CDH5 Proteins) mediates VE-cadherin (show CDH5 Proteins) internalization and endothelial barrier disruption and inflammation.

  8. Data indicate that Pyk2 (show PTK2B Proteins) is a common signaling effector downstream of both G12 (show TCF3 Proteins)/13 and integrin alphaIIbbeta3 signaling, which contributes to thromboxane generation.

  9. Endothelial G13 regulates VEGFR-2 (show KDR Proteins) promoter activity through NF-kappaB (show NFKB1 Proteins) activation.

  10. Negative regulation of Gq-mediated pathways in platelets by G(12/13) pathways through Fyn (show FYN Proteins) kinase

GNA13 Protein Profile

Protein Summary

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

Alternative names and synonyms associated with GNA13

  • guanine nucleotide binding protein (G protein), alpha 13 (Gna13)
  • guanine nucleotide binding protein (G protein), alpha 13a (gna13a)
  • guanine nucleotide binding protein (G protein), alpha 13b (gna13b)
  • guanine nucleotide binding protein (G protein), alpha 13 (GNA13)
  • guanine nucleotide binding protein, alpha 13 (Gna13)
  • AU024132 protein
  • AU043124 protein
  • fj64c01 protein
  • G13 protein
  • Galpha13 protein
  • GNA13 protein
  • wu:fe25e05 protein
  • wu:fj64c01 protein
  • zgc:112436 protein

Protein level used designations for GNA13

guanine nucleotide binding protein, alpha 13 , guanine nucleotide-binding protein subunit alpha-13 , Galpha 13a , Galpha 13b , G-protein alpha 13b , guanine nucleotide binding protein (G protein), alpha 13 , guanine nucleotide-binding protein subunit alpha-13-like , G-protein subunit alpha-13 , g alpha-13

GENE ID SPECIES
303634 Rattus norvegicus
326825 Danio rerio
336333 Danio rerio
417434 Gallus gallus
505611 Bos taurus
100394016 Callithrix jacchus
10672 Homo sapiens
14674 Mus musculus
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