Browse our Minichromosome Maintenance Complex Component 7 Proteins (MCM7)

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Minichromosome Maintenance Complex Component 7 Proteins (MCM7)
On www.antibodies-online.com are 5 Minichromosome Maintenance Complex Component 7 (MCM7) Proteins from 3 different suppliers available. Additionally we are shipping Minichromosome Maintenance Complex Component 7 Antibodies (361) and Minichromosome Maintenance Complex Component 7 Kits (1) and many more products for this protein. A total of 378 Minichromosome Maintenance Complex Component 7 products are currently listed.
Synonyms:
AI747533, anon-EST:Liang-1.66, cdc47, cdc47-2, CG4978, chunp6911, clone 1.66, Dmel\\CG4978, DmeMCM7, DmMCM7, mCDC47, MCM2, mcm7, Mcmd7, Mcp-PCR1, nyz175, P1.1-MCM3, P1CDC47, P85MCM, PCR1, PNAS146, sr:nyz175, xmcm7
list all proteins Gene Name GeneID UniProt
MCM7 4176 P33993
Rat MCM7 MCM7 288532  
MCM7 17220 Q61881

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Minichromosome Maintenance Complex Component 7 Proteins (MCM7) by Origin

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Top referenced Minichromosome Maintenance Complex Component 7 Proteins

  1. Human MCM7 Protein expressed in Wheat germ - ABIN1310563 : Henderson, Hall, Prpic, Hessling, Parker, Sampson, Simkins, Brough, Dixon, Lenz, Knapp, Murphy, Taylor, Fischer, Malinowski: The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia. in Journal of immunological methods 2011 (PubMed)

More Proteins for Minichromosome Maintenance Complex Component 7 Interaction Partners

Human Minichromosome Maintenance Complex Component 7 (MCM7) interaction partners

  1. The results clearly demonstrate 7q21-22 amplification, MCM7, and its intronic miR (show MLXIP Proteins)-25 are the major molecular switches involved in the complex oncogenic circuits of gastric cancer.

  2. High MCM7 expression is associated with non-small cell lung cancer.

  3. MCM4 (show MCM4 Proteins) and MCM7 expression is significantly correlated with Ki-67 (show MKI67 Proteins), Bmi1 (show BMI1 Proteins), and cyclin E (show CCNE1 Proteins) expression in esophageal adenocarcinoma, squamous cell carcinoma and precancerous lesions.

  4. Data suggest that interaction of Mcm10 (show MCM10 Proteins) with Mcm2-7 (show MCM2 Proteins) multimer requires Mcm10 (show MCM10 Proteins) domain that contains amino acids 530-655, which overlaps with domain required for stable retention of Mcm10 (show MCM10 Proteins) on chromatin; Mcm10 (show MCM10 Proteins) conserved domain (amino acids 200-482) is essential for DNA replication; both conserved domain and Mcm2-7 (show MCM2 Proteins)-binding domain are required for full activity of Mcm10 (show MCM10 Proteins).

  5. Results show that the expression of MCM7 gene and its microRNA, miR (show MLXIP Proteins)-106b-25 cluster is reduced under hypoxia.

  6. This MCM4 (show MCM4 Proteins) mutation affected human MCM4 (show MCM4 Proteins)/6/7 complex formation, since the complex containing the mutant MCM4 (show MCM4 Proteins) protein is unstable and the mutant MCM4 (show MCM4 Proteins) protein is tend to be degraded.

  7. Authors found that MCM7 highly expressed in K562 cells rather than that in normal neutrophils. Thus, lentivirus-mediated shRNA targeting MCM7 was used to suppress its endogenous expression in K562 cells and develop a novel therapeutic strategy for leukemia.

  8. MCM7 polymorphisms were associated with survival rate and prognosis in acute myeloid leukemia (show BCL11A Proteins) patients.

  9. The BCL2 (show BCL2 Proteins), MCM7, and CCNE1 (show CCNE1 Proteins) genes might play distinctive roles in cisplatin resistance in bladder cancer.

  10. Purified MCM4 (show MCM4 Proteins)/6/7 complex containing the G364R MCM4 (show MCM4 Proteins) exhibited similar levels of single-stranded DNA binding and ATPase activities to the complex containing wild-type MCM4 (show MCM4 Proteins)

Xenopus laevis Minichromosome Maintenance Complex Component 7 (MCM7) interaction partners

  1. Mcm2-7 (show MCM2 Proteins) associate with Cdc45 (show CDC45 Proteins) and GINS to form a relatively stable CMG (show CASK Proteins) (Cdc45 (show CDC45 Proteins)-MCM-GINS) complex.

Mouse (Murine) Minichromosome Maintenance Complex Component 7 (MCM7) interaction partners

  1. Unique pattern of ORC2 and MCM7 localization during DNA replication licensing in the mouse zygote.

  2. cyclin D1 (show CCND1 Proteins)/CDK4 (show CDK4 Proteins) complexes play a direct role in altering an inhibitory RB.MCM7 complex possibly allowing for setting of the origin in preparation for DNA replication

  3. MCM7 may be a highly informative biomarker for cervical cancer.

  4. Substrate preference and helicase actions of mouse MCM4/6/7 helicase complexes.

  5. Accumulation and dynamics of Mcm7 are described during oogenesis and the first embryonic cell cycle.

  6. cellular DNA replication factor (show CDT1 Proteins) MCM7 is involved in prostate cancer (CaP) and MCM7 gene expression was reduced by green tea catechins

  7. DNA binding and helicase activities of Mcm4 (show MCM4 Proteins)/6/7 are significantly stimulated by Cdt1 (show CDT1 Proteins)

Minichromosome Maintenance Complex Component 7 (MCM7) Protein Profile

Protein Summary

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with Minichromosome Maintenance Complex Component 7 (MCM7)

  • Minichromosome maintenance 7 (Mcm7)
  • Mcm7p (MCM7)
  • chromatin binding/ DNA replication (CDC47)
  • minichromosome maintenance complex component 2 (MCM2)
  • minichromosome maintenance complex component 7 (MCM7)
  • MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) (mcm7)
  • minichromosome maintenance complex component 7 (mcm7-b)
  • minichromosome maintenance complex component 7 (Mcm7)
  • minichromosome maintenance deficient 7 (S. cerevisiae) (Mcm7)
  • AI747533 protein
  • anon-EST:Liang-1.66 protein
  • cdc47 protein
  • cdc47-2 protein
  • CG4978 protein
  • chunp6911 protein
  • clone 1.66 protein
  • Dmel\\CG4978 protein
  • DmeMCM7 protein
  • DmMCM7 protein
  • mCDC47 protein
  • MCM2 protein
  • mcm7 protein
  • Mcmd7 protein
  • Mcp-PCR1 protein
  • nyz175 protein
  • P1.1-MCM3 protein
  • P1CDC47 protein
  • P85MCM protein
  • PCR1 protein
  • PNAS146 protein
  • sr:nyz175 protein
  • xmcm7 protein

Protein level used designations for MCM7

CG4978-PA , Mcm7-PA , minichromosome maintenance 7 , minichromosome maintenance-PCR1 , hypothetical protein , minichromosome maintenance complex component 7 , minichromosome maintenance protein 2 , minichromosome maintenance protein 7 , minichromosome maintenance complex component 2 , DNA replication licensing factor MCM7-like , DNA replication licensing factor MCM7 , CDC47 homolog , homolog of S. cerevisiae Cdc47 , minichromosome maintenance deficient 7 , CDC47 homolog B , CDC47-2p , DNA replication licensing factor mcm7-B , minichromosome maintenance protein 7-B , xMCM7-B , MCM7 minichromosome maintenance deficient 7 , mini chromosome maintenance deficient 7

GENE ID SPECIES
39014 Drosophila melanogaster
852501 Saccharomyces cerevisiae S288c
3645780 Candida albicans SC5314
3645802 Candida albicans SC5314
460668 Pan troglodytes
472460 Pan troglodytes
484622 Canis lupus familiaris
710766 Macaca mulatta
710888 Macaca mulatta
100053690 Equus caballus
100088867 Ornithorhynchus anatinus
100337896 Oryctolagus cuniculus
100401193 Callithrix jacchus
100432206 Pongo abelii
100442048 Pongo abelii
100481582 Ailuropoda melanoleuca
192333 Danio rerio
4176 Homo sapiens
380414 Xenopus laevis
479737 Canis lupus familiaris
288532 Rattus norvegicus
539924 Bos taurus
17220 Mus musculus
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