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Browse our anti-HGS (HGS) Antibodies

Full name:
anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate Antibodies (HGS)
On www.antibodies-online.com are 111 Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) Antibodies from 19 different suppliers available. Additionally we are shipping HGS Kits (9) and HGS Proteins (6) and many more products for this protein. A total of 132 HGS products are currently listed.
Synonyms:
CG2903, Dmel\\CG2903, Hgr, Hrs, HRS-2, l(2)23AB5, l(2)23Ad, l(2)23Ad(Hrs), vps27, ZFYVE8

Most Popular Reactivities for anti-HGS (HGS) Antibodies

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anti-Human HGS Antibodies:

anti-Rat (Rattus) HGS Antibodies:

anti-Mouse (Murine) HGS Antibodies:

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Top referenced anti-HGS Antibodies

  1. Human Polyclonal HGS Primary Antibody for IHC (p), WB - ABIN388936 : Kirk, Chin, Li: GRIF1 binds Hrs and is a new regulator of endosomal trafficking. in Journal of cell science 2006 (PubMed)
    Show all 3 references for ABIN388936

  2. Human Polyclonal HGS Primary Antibody for EIA, IHC (p) - ABIN357582 : Sasaki, Sugamura: Involvement of Hgs/Hrs in signaling for cytokine-mediated c-fos induction through interaction with TAK1 and Pak1. in The Journal of biological chemistry 2001 (PubMed)
    Show all 3 references for ABIN357582

  3. Human Monoclonal HGS Primary Antibody for IF, RNAi - ABIN563958 : McLeod, Zhou, Li, Wang, He: The class III kinase Vps34 promotes T lymphocyte survival through regulating IL-7R? surface expression. in Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)

  4. Human Polyclonal HGS Primary Antibody for ELISA, WB - ABIN563957 : Calabia-Linares, Robles-Valero, de la Fuente, Perez-Martinez, Martín-Cofreces, Alfonso-Pérez, Gutierrez-Vázquez, Mittelbrunn, Ibiza, Urbano-Olmos, Aguado-Ballano, Sánchez-Sorzano, Sanchez-Madrid et al.: Endosomal clathrin drives actin accumulation at the immunological synapse. ... in Journal of cell science 2011 (PubMed)

  5. Human Polyclonal HGS Primary Antibody for IHC, ELISA - ABIN185612 : Kobayashi, Tanaka, Asao, Miura, Kyuuma, Semura, Ishii, Sugamura: Hrs, a mammalian master molecule in vesicular transport and protein sorting, suppresses the degradation of ESCRT proteins signal transducing adaptor molecule 1 and 2. in The Journal of biological chemistry 2005 (PubMed)

  6. Human Polyclonal HGS Primary Antibody for IF, IHC - ABIN1533491 : Lu, Komada, Kitamura: Human Hrs, a tyrosine kinase substrate in growth factor-stimulated cells: cDNA cloning and mapping of the gene to chromosome 17. in Gene 1998 (PubMed)

More Antibodies against HGS Interaction Partners

Fruit Fly (Drosophila melanogaster) Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) interaction partners

  1. Hrs is dispensable for cytokinesis. Finally, it was found that although Drosophila Hrs does not localize at acrosome, the other endosomal markers--Rab4, Rab7, and Rab11--are detected at the organelle.

  2. Drosophila epithelia lacking Hrs and Stam (show STAM Antibodies), accumulate Notch (show NOTCH1 Antibodies) and Dome in endosomes, maintain normal apico-basal polarity and proliferation control and do not show ectopic Notch (show NOTCH1 Antibodies) signaling activation.

  3. Hrs mediates Smo trafficking in the late endosome by not only promoting Smo ubiquitination but also blocking Smo phosphorylation.

  4. these data support a model in which Ubpy (show USP8 Antibodies) plays a dual role in both cargo deubiquitylation and the ESCRT-0 subunit Hrs stability during development.

  5. show that the endosomal proteins Myopic (Mop (show OPN4 Antibodies)) and Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) are required for the activation of the Toll (show TLR4 Antibodies) signaling pathway.

Human Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) interaction partners

  1. Results demonstrate the existence of crosstalk between beta-catenin signaling and HGS in two different types of cancer (hepatoblastoma and colorectal).

  2. ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM (show STAM Antibodies)) and the complex formation with STAM (show STAM Antibodies) promotes its endosomal dissociation.

  3. we identified an interaction between EsxH, which is secreted by the Esx-3 TSSS, and human hepatocyte growth factor-regulated tyrosine kinase substrate (Hgs/Hrs), a component of the endosomal sorting complex required for transport (ESCRT).

  4. the role for tumoral c-Met expression or sMet/HGF (show HGF Antibodies) levels as upfront selection criterion or predictive biomarkers deserve further study in this emerging area of therapeutic focus in RCC (show XRCC1 Antibodies)

  5. Hrs tyrosine phosphorylation detected upon EGF (show EGF Antibodies)-stimulation.

  6. Hrs inhibits HIV-1 production by inhibiting citron kinase (show CIT Antibodies)-mediated exocytosis.

  7. ESCRT-0 component HRS is required for HIV-1 Vpu-mediated BST-2/tetherin (show BST2 Antibodies) down-regulation.

  8. Plasma hepatocyte growth factor (show HGF Antibodies) is associated with periampullary cancer.

  9. hSpry2 binds to the endocytic regulatory protein, hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) and blocks intracellular signal propagation.

  10. The HRS domain required for merlin (show NF2 Antibodies) binding is narrowed to a region (residues 470-497) containing the predicted coiled-coil domain whereas the major domain responsible for HRS growth suppression is distinct (residues 498-550).

Cow (Bovine) Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) interaction partners

  1. structure of a complex of Hrs-UIM and ubiquitin at 1.7-A resolution [ubiquitin]

Mouse (Murine) Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) interaction partners

  1. HGS expression in the nervous system is developmentally regulated.HGS is required for motor neuron function.

  2. Smooth Muscle Hgs Deficiency Leads to Impaired Esophageal Motility.

  3. ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM (show STAM Antibodies)) and the complex formation with STAM (show STAM Antibodies) promotes its endosomal dissociation.

  4. A new mechanism to modify BMP signaling by Hgs during early mouse development.

  5. Hrs is a master molecule that controls in part the degradation of STAM1 (show STAM Antibodies) and the accumulation of ubiquitinated proteins

  6. Data suggest that Hrs regulates the KGFR (show FGFR2 Antibodies) degradative pathway, but not its juxtanuclear recycling transport, and that Hrs recruitment to the receptor, but not its ligand-induced phosphorylation, could be required for its function.

  7. Nedd4-2 (show NEDD4L Antibodies) induces binding of ENaC (show SCNN1A Antibodies) to Hrs, which mediates the sorting decision between ENaC (show SCNN1A Antibodies) degradation and recycling.

  8. Peptidergic versus nonpeptidergic specification depends on a balance between HGF (show HGF Antibodies)-Met signaling and Runx1 (show RUNX1 Antibodies) extinction/maintenance in primary nociceptive neurons.

  9. Src (show SRC Antibodies) phosphorylates Hrs in vitro & in vivo. Hrs is phosphorylated in Src (show SRC Antibodies)-, Yes- & Fyn (show FYN Antibodies)-negative cells. 10-20% is phosphorylated after EGF (show EGF Antibodies) stimulation at multiple tyrosines in different parts of Hrs by several kinases downstream of the EGF receptor (show EGFR Antibodies).

  10. Hrs, Eps15 (show EPS15 Antibodies), and STAM (show STAM Antibodies) proteins function in a multivalent complex that sorts ubiquitinated proteins into the multivesicular body pathway.

HGS Antigen Profile

Antigen Summary

The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.

Alternative names and synonyms associated with HGS

  • Hepatocyte growth factor regulated tyrosine kinase substrate (Hrs) antibody
  • hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) antibody
  • hepatocyte growth factor-regulated tyrosine kinase substrate (Hgs) antibody
  • HGF-regulated tyrosine kinase substrate (Hgs) antibody
  • CG2903 antibody
  • Dmel\\CG2903 antibody
  • Hgr antibody
  • Hrs antibody
  • HRS-2 antibody
  • l(2)23AB5 antibody
  • l(2)23Ad antibody
  • l(2)23Ad(Hrs) antibody
  • vps27 antibody
  • ZFYVE8 antibody

Protein level used designations for HGS

CG2903-PA , CG2903-PB , CG2903-PC , Hrs-PA , Hrs-PB , Hrs-PC , hepatocyte growth factor regulated tyrosine kinase , hepatocyte growth factor regulated tyrosine kinase substrate , hepatocyte growth factor-regulated tyrosine kinase substrate , hepatocyte growth-factor-regulated substrate , human growth factor-regulated tyrosine kinase substrate , protein pp110 , HGF-regulated tyrosine kinase substrate , SNAP-25-interacting protein Hrs-2

GENE ID SPECIES
33458 Drosophila melanogaster
9146 Homo sapiens
56084 Rattus norvegicus
511582 Bos taurus
15239 Mus musculus
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