HGS antibody (N-Term)

Catalog No. ABIN545153

Product Details anti-HGS Antibody

Target: HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HGS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of HGS.

Cross-Reactivity: Human, Mouse

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human HGS.

Application Details

Application Notes: ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-HGS antibody (ABIN545153)

Kirk, Chin, Li: "GRIF1 binds Hrs and is a new regulator of endosomal trafficking." in: Journal of cell science, Vol. 119, Issue Pt 22, pp. 4689-701, (2006) (PubMed).

Sasaki, Sugamura: "Involvement of Hgs/Hrs in signaling for cytokine-mediated c-fos induction through interaction with TAK1 and Pak1." in: The Journal of biological chemistry, Vol. 276, Issue 32, pp. 29943-52, (2001) (PubMed).

Miura, Takeshita, Asao, Kimura, Murata, Sasaki, Hanai, Beppu, Tsukazaki, Wrana, Miyazono, Sugamura: "Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA." in: Molecular and cellular biology, Vol. 20, Issue 24, pp. 9346-55, (2000) (PubMed).

Target Details for HGS

Target: HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))

Alternative Name: HGS / HRS (HGS Products)

Synonyms: HRS antibody, Hrs antibody, fi34f05 antibody, zgc:63492 antibody, wu:fi34f05 antibody, Hgr antibody, ZFYVE8 antibody, CG2903 antibody, Dmel\\CG2903 antibody, HRS-2 antibody, Vps27 antibody, hrs antibody, l(2)23AB5 antibody, l(2)23Ad antibody, l(2)23Ad(Hrs) antibody, vps27 antibody, hgs antibody, hepatocyte growth factor-regulated tyrosine kinase substrate antibody, HGF-regulated tyrosine kinase substrate antibody, Hepatocyte growth factor regulated tyrosine kinase substrate antibody, hepatocyte growth factor-regulated tyrosine kinase substrate L homeolog antibody, HGS antibody, Hgs antibody, hgs antibody, Hrs antibody, hgs.L antibody

Gene ID: 9146

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Synaptic Vesicle Exocytosis, EGFR Downregulation