Browse our NCK2 Proteins (NCK2)

Full name:
NCK Adaptor Protein 2 Proteins (NCK2)
On are 14 NCK Adaptor Protein 2 (NCK2) Proteins from 5 different suppliers available. Additionally we are shipping NCK2 Antibodies (81) and many more products for this protein. A total of 100 NCK2 products are currently listed.
4833426I10Rik, Grb4, Nck-2, NCK2, NCKbeta
list all proteins Gene Name GeneID UniProt
NCK2 8440 O43639
Rat NCK2 NCK2 316369  
NCK2 17974 O55033

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NCK2 Proteins (NCK2) by Origin

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More Proteins for NCK2 Interaction Partners

Human NCK Adaptor Protein 2 (NCK2) interaction partners

  1. Nck1 (show NCK1 Proteins) and Nck2 Interact with WTIP (show WTIP Proteins). Nck1 (show NCK1 Proteins)/2 integrates nephrin (show NPHS1 Proteins) with the Hippo kinase cascade through association with the adaptor protein WTIP (show WTIP Proteins).

  2. Data suggest that PINCH1 (show LIMS1 Proteins) and Nck2 critically participate in the regulation of cellular radiosensitivity and EGFR (show EGFR Proteins) function and downstream signaling in a cellular model of human squamous cell carcinoma.

  3. Tir-Intimin interaction recruits the Nck (show NCK1 Proteins) adaptor to a Tir tyrosine phosphorylated residue where it activates neural Wiskott-Aldrich syndrome protein (N-WASP (show WASL Proteins)).

  4. Proteasomal degradation of Nck1 but not Nck2 regulates RhoA activation and actin dynamics.

  5. NCK2 is involved in the susceptibility to opiates addiction.

  6. The hNck2 SH3 domain also exhibited pH dependent monomer-dimer transition.

  7. Data show that both HK2 (show HK2 Proteins) and NCK2 are expressed in the retinal ganglion cell layer.

  8. Nck2 effectively influences human melanoma phenotype progression.

  9. p21-Activated kinase 3 (PAK3) protein regulates synaptic transmission through its interaction with the Nck2/Grb4 protein adaptor.

  10. Nck2 is an adaptor protein composed of 3N-SH3 domains followed by a unique Cterminal SH2 domain. It interacts with PINCH (show LIMS1 Proteins) in integrin signal transduction, cell migratio and survival. Review.

Mouse (Murine) NCK Adaptor Protein 2 (NCK2) interaction partners

  1. Authors propose that Nck2 should be further investigated as a regulator of the reliance of white adipose tissue on hyperplasia versus hypertrophy during adipose tissue expansion, and hence, as a potential novel molecular target in obesity.

  2. Findings reveal that Nck2 is a novel regulator of adiposity and suggest that Nck2 is important in limiting WAT expansion and dysfunction in mice and humans.

  3. Inactivation of NCK2 (and NCK1 (show NCK1 Proteins)) inhibits endothelial cell polarity.

  4. These results reveal that Nck (show NCK1 Proteins) regulates preosteoblastic/osteoblastic migration and bone mass.

  5. we show that the non-catalytic region of tyrosine kinase (show NCK1 Proteins) adaptor (NCK (show NCK1 Proteins)) proteins 1 and 2 are distributed in the developing spinal cord

  6. Mouse embryos lacking endothelial Nck1 (show NCK1 Proteins)/2 expression develop extensive angiogenic defects that result in lethality at about embryonic day 10.

  7. Data show that only Nck2 is required for the Slit1 (show SLIT1 Proteins)-induced changes in cortical neuron morphology in vitro.

  8. These results revealed an essential role for HSF4-mediated SKAP2 expression in the regulation of actin reorganization during lens differentiation.

  9. The Cas (show CTNND1 Proteins) utilizes Nck2 to activate Cdc42 (show CDC42 Proteins) and induce cell polarization in response to wound healing.

  10. Nck1 (show NCK1 Proteins) and Nck2 have roles in cell movement and cytoskeletal organization

NCK2 Protein Profile

Protein Summary

This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with NCK2

  • NCK adaptor protein 2 (NCK2)
  • NCK adaptor protein 2 (LOC100227348)
  • NCK adaptor protein 2 (LOC100353755)
  • NCK adaptor protein 2 (Nck2)
  • non-catalytic region of tyrosine kinase adaptor protein 2 (Nck2)
  • 4833426I10Rik protein
  • Grb4 protein
  • Nck-2 protein
  • NCK2 protein
  • NCKbeta protein

Protein level used designations for NCK Adaptor Protein 2 Proteins (NCK2)

NCK adaptor protein 2 , cytoplasmic protein NCK2-like , SH2/SH3 adaptor protein NCK-beta , cytoplasmic protein NCK2 , growth factor receptor-bound protein 4 , noncatalytic region of tyrosine kinase, beta , non-catalytic region of tyrosine kinase adaptor protein 2

459472 Pan troglodytes
713287 Macaca mulatta
100014693 Monodelphis domestica
100227348 Taeniopygia guttata
100353755 Oryctolagus cuniculus
100401429 Callithrix jacchus
100452789 Pongo abelii
100475197 Ailuropoda melanoleuca
100544012 Meleagris gallopavo
100607084 Nomascus leucogenys
8440 Homo sapiens
316369 Rattus norvegicus
418727 Gallus gallus
481319 Canis lupus familiaris
526430 Bos taurus
17974 Mus musculus
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