NCK2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all NCK2 Proteins
- NCK2 (NCK Adaptor Protein 2 (NCK2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NCK2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NCK2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NCK2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NCK2 (NCK Adaptor Protein 2 (NCK2))
- Alternative Name
- Nck2 (NCK2 Products)
- Synonyms
- GRB4 Protein, NCKbeta Protein, NCK2 Protein, 4833426I10Rik Protein, Grb4 Protein, Nck-2 Protein, Nck2 Protein, zgc:55283 Protein, fd20h08 Protein, im:7147817 Protein, si:ch211-147g19.3 Protein, wu:fd20h08 Protein, zgc:92024 Protein, NCK adaptor protein 2 Protein, cytoplasmic protein NCK2-like Protein, non-catalytic region of tyrosine kinase adaptor protein 2 Protein, NCK adaptor protein 2a Protein, NCK adaptor protein 2b Protein, NCK2 Protein, Nck2 Protein, LOC100227348 Protein, nck2a Protein, nck2b Protein
- Background
- This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
- Molecular Weight
- 42.7 kDa
- NCBI Accession
- NP_001004720
- Pathways
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization
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