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NCK2 Protein (AA 1-380, full length) (His-SUMO Tag)

NCK2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5709993
  • Target See all NCK2 Proteins
    NCK2 (NCK Adaptor Protein 2 (NCK2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-380, full length
    Origin
    • 6
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This NCK2 protein is labelled with His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MTEEVIVIAK WDYTAQQDQE LDIKKNERLW LLDDSKTWWR VRNAANRTGY VPSNYVERKN SLKKGSLVKN LKDTLGLGKT RRKTSARDAS PTPSTDAEYP ANGSGADRIY DLNIPAFVKF AYVAEREDEL SLVKGSRVTV MEKCSDGWWR GSYNGQIGWF PSNYVLEEVD EAAAESPSFL SLRKGASLSN GQGSRVLHVV QTLYPFSSVT EEELNFEKGE TMEVIEKPEN DPEWWKCKNA RGQVGLVPKN YVVVLSDGPA LHPAHAPQIS YTGPSSSGRF AGREWYYGNV TRHQAECALN ERGVEGDFLI RDSESSPSDF SVSLKASGKN KHFKVQLVDN VYCIGQRRFH TMDELVEHYK KAPIFTSEHG EKLYLVRALQ
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product NCK2 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    NCK2 (NCK Adaptor Protein 2 (NCK2))
    Alternative Name
    NCK2 (NCK2 Products)
    Synonyms
    GRB4 Protein, NCKbeta Protein, NCK2 Protein, 4833426I10Rik Protein, Grb4 Protein, Nck-2 Protein, Nck2 Protein, zgc:55283 Protein, fd20h08 Protein, im:7147817 Protein, si:ch211-147g19.3 Protein, wu:fd20h08 Protein, zgc:92024 Protein, NCK adaptor protein 2 Protein, cytoplasmic protein NCK2-like Protein, non-catalytic region of tyrosine kinase adaptor protein 2 Protein, NCK adaptor protein 2a Protein, NCK adaptor protein 2b Protein, NCK2 Protein, Nck2 Protein, LOC100227348 Protein, nck2a Protein, nck2b Protein
    Background
    Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling.
    Molecular Weight
    58.9 kDa
    UniProt
    O43639
    Pathways
    EGFR Signaling Pathway, Regulation of Actin Filament Polymerization
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