NCK2 Protein (AA 1-380, full length) (His-SUMO Tag)
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- Target See all NCK2 Proteins
- NCK2 (NCK Adaptor Protein 2 (NCK2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-380, full length
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NCK2 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MTEEVIVIAK WDYTAQQDQE LDIKKNERLW LLDDSKTWWR VRNAANRTGY VPSNYVERKN SLKKGSLVKN LKDTLGLGKT RRKTSARDAS PTPSTDAEYP ANGSGADRIY DLNIPAFVKF AYVAEREDEL SLVKGSRVTV MEKCSDGWWR GSYNGQIGWF PSNYVLEEVD EAAAESPSFL SLRKGASLSN GQGSRVLHVV QTLYPFSSVT EEELNFEKGE TMEVIEKPEN DPEWWKCKNA RGQVGLVPKN YVVVLSDGPA LHPAHAPQIS YTGPSSSGRF AGREWYYGNV TRHQAECALN ERGVEGDFLI RDSESSPSDF SVSLKASGKN KHFKVQLVDN VYCIGQRRFH TMDELVEHYK KAPIFTSEHG EKLYLVRALQ
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product NCK2 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- NCK2 (NCK Adaptor Protein 2 (NCK2))
- Alternative Name
- NCK2 (NCK2 Products)
- Synonyms
- GRB4 Protein, NCKbeta Protein, NCK2 Protein, 4833426I10Rik Protein, Grb4 Protein, Nck-2 Protein, Nck2 Protein, zgc:55283 Protein, fd20h08 Protein, im:7147817 Protein, si:ch211-147g19.3 Protein, wu:fd20h08 Protein, zgc:92024 Protein, NCK adaptor protein 2 Protein, cytoplasmic protein NCK2-like Protein, non-catalytic region of tyrosine kinase adaptor protein 2 Protein, NCK adaptor protein 2a Protein, NCK adaptor protein 2b Protein, NCK2 Protein, Nck2 Protein, LOC100227348 Protein, nck2a Protein, nck2b Protein
- Background
- Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling.
- Molecular Weight
- 58.9 kDa
- UniProt
- O43639
- Pathways
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization
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