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DLC1 antibody (N-Term)

Verified DLC1 Reactivity: Human, Mouse IHC, ELISA, IF Host: Goat Polyclonal unconjugated
Catalog No. ABIN185264
  • Target See all DLC1 Antibodies
    DLC1 (Deleted in Liver Cancer 1 (DLC1))
    Binding Specificity
    • 15
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 36
    • 8
    • 8
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 36
    • 2
    Goat
    Clonality
    • 38
    Polyclonal
    Conjugate
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DLC1 antibody is un-conjugated
    Application
    • 13
    • 13
    • 10
    • 9
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    Purpose
    DLC1 (Isoforms 1 and 3)
    Sequence
    SVAIRKRSWE EHC
    Specificity
    This antibody is expected to recognise isoforms 1 and 3 ( NP_872584.2 and NP_079043.3 resp) but NOT isoform 2 (NP_006085.2).
    Cross-Reactivity
    Human, Mouse, Pig
    Purification
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Grade
    Verified
    Immunogen
    Peptide with sequence SVAIRKRSWEEHC, from the N Terminus of the protein sequence according to NP_872584.2, NP_079043.3.
    Isotype
    IgG
  • Application Notes

    Immunohistochemistry: Paraffin embedded Mouse Adrenal Gland. Recommended concentration: 4 μg/mL.

    Peptide ELISA: antibody detection limit dilution 1:64000.

    Comment

    Immunofluorescence: Expression of the protein seen in the cytoplasm and nucleus of U251 and U2OS cells. Recommended concentration: 10μg/ml.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Minimize freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Ko, Yeung, Wong, Chan, Poon, Ng, Yam: "Deleted in liver cancer 1 isoforms are distinctly expressed in human tissues, functionally different and under differential transcriptional regulation in hepatocellular carcinoma." in: Liver international : official journal of the International Association for the Study of the Liver, Vol. 30, Issue 1, pp. 139-48, (2009) (PubMed).

  • Target
    DLC1 (Deleted in Liver Cancer 1 (DLC1))
    Alternative Name
    DLC1 (DLC1 Products)
    Synonyms
    ARHGAP7 antibody, HP antibody, STARD12 antibody, p122-RhoGAP antibody, rhogap7 antibody, DLC-1 antibody, StARD12 antibody, Dlc-1 antibody, A730069N07Rik antibody, Arhgap7 antibody, dlc-1 antibody, RhoGAP antibody, Dlc1 antibody, DLC1 Rho GTPase activating protein antibody, DLC1 Rho GTPase activating protein S homeolog antibody, rho GTPase-activating protein 7 antibody, deleted in liver cancer 1 antibody, DLC1 antibody, dlc1.S antibody, dlc1 antibody, LOC100456847 antibody, Dlc1 antibody, LOC100729904 antibody
    Background
    DLC1, HP, ARHGAP7, STARD12, FLJ21120, p122-RhoGAP, deleted in liver cancer 1, Rho-GTPase-activating protein 7, START domain containing protein 12, StAR-related lipid, transfer protein 12, StAR-related lipid transfer (START) domain containing 12, deleted
    Gene ID
    10395, 50768
    NCBI Accession
    NP_872584, NP_079043
    Pathways
    Tube Formation, Positive Regulation of Endopeptidase Activity
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