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PITRM1 antibody (AA 758-1037)

PITRM1 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7164274
  • Target See all PITRM1 Antibodies
    PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 758-1037
    Reactivity
    • 31
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 29
    • 3
    Rabbit
    Clonality
    • 30
    • 2
    Polyclonal
    Conjugate
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    This PITRM1 antibody is un-conjugated
    Application
    • 30
    • 18
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Cross-Reactivity
    Human, Mouse
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Presequence protease, mitochondrial protein (758-1037AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))
    Alternative Name
    PITRM1 (PITRM1 Products)
    Synonyms
    MP1 antibody, PreP antibody, 2310012C15Rik antibody, AA410010 antibody, MP-1 antibody, Ntup1 antibody, mKIAA1104 antibody, PITRM1 antibody, wu:fa03d09 antibody, zgc:55469 antibody, pitrilysin metallopeptidase 1 antibody, pitrilysin metallepetidase 1 antibody, pitrilysin metallopeptidase 1 L homeolog antibody, PITRM1 antibody, Pitrm1 antibody, pitrm1.L antibody, pitrm1 antibody
    Background

    Background: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

    Aliases: hMP1 antibody, hPreP antibody, KIAA1104 antibody, Metalloprotease 1 antibody, MGC138192 antibody, MGC141929 antibody, mitochondrial antibody, MP1 antibody, Pitrilysin metallopeptidase 1 antibody, Pitrilysin metalloproteinase 1 antibody, PITRM 1 antibody, PITRM1 antibody, PreP antibody, PreP peptidasome antibody, PREP_HUMAN antibody, Presequence protease antibody, Presequence protease mitochondrial antibody

    UniProt
    Q5JRX3
    Pathways
    PI3K-Akt Signaling, SARS-CoV-2 Protein Interactome
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