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COPS5 antibody

COPS5 Reactivity: Human WB, IHC, IF, ChIP Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7266497
  • Target See all COPS5 Antibodies
    COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
    Reactivity
    • 65
    • 49
    • 28
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 59
    • 9
    • 2
    Rabbit
    Clonality
    • 54
    • 16
    Monoclonal
    Conjugate
    • 35
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COPS5 antibody is un-conjugated
    Application
    • 46
    • 14
    • 14
    • 14
    • 14
    • 9
    • 9
    • 7
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)
    Purpose
    JAB1/CSN5/COPS5 Rabbit mAb
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthesized peptide derived from human JAB1/CSN5/COPS5
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,ChIP,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
    Alternative Name
    COPS5 (COPS5 Products)
    Synonyms
    BcDNA.LD14392 antibody, BcDNA:LD14392 antibody, CG14884 antibody, CH5 antibody, CSN-5 antibody, Csn5 antibody, DCH5 antibody, Dch5 antibody, Dmel\\CG14884 antibody, JAB1 antibody, JAB1/CSN5 antibody, Jab1 antibody, JadBp antibody, csn5 antibody, dch5 antibody, jab1/csn5 antibody, l(3)89Cf antibody, l(3)L4032 antibody, l(3)M203 antibody, quo antibody, COPS5 antibody, MGC76063 antibody, AI303502 antibody, CSN5 antibody, Mov34 antibody, Sgn5 antibody, zgc:73130 antibody, MOV-34 antibody, SGN5 antibody, COP9 signalosome subunit 5 antibody, COP9 signalosome complex subunit 5 antibody, COP9 signalosome subunit 5 S homeolog antibody, CSN5 antibody, COPS5 antibody, cops5 antibody, CpipJ_CPIJ012314 antibody, Bm1_46585 antibody, VDBG_06932 antibody, LOAG_01443 antibody, csn5 antibody, Cops5 antibody, cops5.S antibody, csn-5 antibody
    Background
    The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008],CSN5, JAB1, MOV-34, SGN5,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell cycle inhibitors,Epigenetics & Nuclear Signaling,Tumor suppressors,Tumor suppressors_p53 pathway,Ubiquitin,COPS5
    Molecular Weight
    38kDa
    Gene ID
    10987
    UniProt
    Q92905
    Pathways
    Cell Division Cycle
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