CACNA1E antibody (Internal Region)
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- Target See all CACNA1E Antibodies
- CACNA1E (Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CACNA1E antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- CACNA1E Antibody detects endogenous levels of total CACNA1E.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CACNA1E, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product CACNA1E Primary Antibody
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anti-Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E) antibody
CACNA1E Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E) (AA 2014-2313) antibodyCACNA1E Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E) (AA 892-907), (Intracellular) antibodyCACNA1E Reactivity: Human, Rat, Mouse WB, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- CACNA1E (Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E))
- Alternative Name
- CACNA1E (CACNA1E Products)
- Synonyms
- caV2.3 antibody, CACNA1E antibody, BII antibody, CACH6 antibody, CACNL1A6 antibody, Cav2.3 antibody, A430040I15 antibody, Cach6 antibody, Cacnl1a6 antibody, Cchra1 antibody, alpha1E antibody, CACHA1E antibody, calcium voltage-gated channel subunit alpha1 E antibody, calcium channel, voltage-dependent, R type, alpha 1E subunit antibody, CACNA1E antibody, cacna1e antibody, Cacna1e antibody
- Background
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Description: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel, and partially by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), omega-conotoxin-GVIA (omega-CTx-GVIA), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing.
Gene: CACNA1E
- Molecular Weight
- 262 kDa
- Gene ID
- 777
- UniProt
- Q15878
- Pathways
- Carbohydrate Homeostasis
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