GLUT1 antibody (AA 92-492)
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- Target See all GLUT1 (SLC2A1) Antibodies
- GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))
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Binding Specificity
- AA 92-492
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GLUT1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Purpose
- Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 1(SLC2A1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 1(SLC2A1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Gene Name: solute carrier family 2 (facilitated glucose transporter), member 1
Protein Name: Solute carrier family 2, facilitated glucose transporter member 1 - Purification
- Immunogen affinity purified.
- Immunogen
- E.coli-derived human SLC2A1 recombinant protein (Position: R92-V492). Human SLC2A1 shares 98% and 98.3% amino acid (aa) sequence identity with mouse and rat SLC2A1, respectively.
- Isotype
- IgG
- Top Product
- Discover our top product SLC2A1 Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for SLC2A1 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) , IHC(F) and ICC.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma." in: International journal of oncology, Vol. 53, Issue 2, pp. 551-566, (2018) (PubMed).
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lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma." in: International journal of oncology, Vol. 53, Issue 2, pp. 551-566, (2018) (PubMed).
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- Target
- GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))
- Alternative Name
- SLC2A1 (SLC2A1 Products)
- Synonyms
- DYT17 antibody, DYT18 antibody, DYT9 antibody, EIG12 antibody, GLUT antibody, GLUT1 antibody, GLUT1DS antibody, HTLVR antibody, PED antibody, Glut-1 antibody, Glut1 antibody, GLUTB antibody, GTG1 antibody, Gtg3 antibody, RATGTG1 antibody, SLC2A1 antibody, GLT1 antibody, GLUCOSE TRANSPORTER 1 antibody, T21H19.70 antibody, T21H19_70 antibody, plastidic GLC translocator antibody, glut1 antibody, ped antibody, slc2a1 antibody, slc2a14 antibody, solute carrier family 2 member 1 antibody, solute carrier family 2 (facilitated glucose transporter), member 1 antibody, plastidic GLC translocator antibody, solute carrier family 2 (facilitated glucose transporter), member 1 L homeolog antibody, SLC2A1 antibody, Slc2a1 antibody, PGLCT antibody, slc2a1.L antibody
- Background
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GLUT1, also known as SLC2A1, is a major glucose transporter in the mammalian blood-brain barrier whose gene is mapped to 1p35-p31.3 and contains 10 exons. It is present at high levels in primate erythrocytes and brain endothelial cells. Not only can transport dehydroascorbic acid (the oxidized form of vitamin C) into the brain, GLUT1 is also likely to contribute to HTLV-associated disorders through interacting with HTLV envelope glycoproteins. Functionally, GLUT1 deficiency causes a decrease in embryonic glucose uptake and apoptosis, which may be involved in diabetic embryopathy, by contrast, an increased expression of GLUT1 in some malignant tumors may suggest a role for glucose-derivative tracers to detect in vivo thyroid cancer metastases by positron-emission tomography scanning.
Synonyms: DYT17 antibody|DYT18 antibody|erythrocyte/brain antibody|Erythrocyte/brain HepG2 glucose transporter antibody|Erythrocyte/hepatoma glucose transporter antibody|facilitated glucose transporter member 1 antibody|Glucose transporter 1 antibody|Glucose transporter type 1 antibody|Glucose transporter type 1 erythrocyte/brain antibody|Glucose transporter type 1, erythrocyte/brain antibody|GLUT antibody|GLUT-1 antibody|GLUT1 antibody|GLUT1DS antibody| GLUTB antibody|GT1 antibody|GTG1 antibody|Gtg3 antibody|GTR1_HUMAN antibody|HepG2 glucose transporter antibody|MGC141895 antibody|MGC141896 antibody|PED antibody|RATGTG1 antibody| SLC2A 1 antibody|SLC2A1 antibody|Solute carrier family 2 (facilitated glucose transporter), member 1 antibody|Solute carrier family 2 antibody|Solute carrier family 2 facilitated glucose transporter member 1 antibody|Solute carrier family 2, facilitated glucose transporter member 1 antibody - Gene ID
- 6513
- UniProt
- P11166
- Pathways
- Sensory Perception of Sound, Dicarboxylic Acid Transport, Warburg Effect
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