×
For best experience we recommend to activate Javascript in your browser.
IKBKB antibody (AA 630-730)
IKBKB
Reactivity: Human
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IKBKB Antibody
(hide)
Target
See all IKBKB Antibodies
IKBKB
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
Binding Specificity
All epitopes for IKBKB antibodies
AA 630-730
Reactivity
All reactivities for IKBKB antibodies
Human
Host
All hosts for IKBKB antibodies
Rabbit
Clonality
All clonalities for IKBKB antibodies
Polyclonal
Conjugate
All conjugates for IKBKB antibodies
This IKBKB antibody is un-conjugated
Application
All applications for IKBKB antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Sequence
EEVVSLMNED EKTVVRLQEK RQKELWNLLK IACSKVRGPV SGSPDSMNAS RLSQPGQLMS QPSTASNSLP EPAKKSEELV AEAHNLCTLL ENAIQDTVRE Q
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 630-730 of human IKKbeta (NP_001547.1).
Isotype
IgG
Alternatives
(show)
Application Details
(hide)
Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:200
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
References for anti-IKBKB antibody (ABIN3022876)
(hide)
Wang, Wang, Liu, Wang, Xu, Liu, Zhu, Chen, Situ, Lin : "Broadleaf Mahonia attenuates granulomatous lobular mastitis‑associated inflammation by inhibiting CCL‑5 expression in macrophages. " in: International journal of molecular medicine , Vol. 41 , Issue 1 , pp. 340-352 , (2018 ) (PubMed ).
Gao, Yang, Yuan, Huang, Xu, Mao, Yuan, Bi : "TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration. " in: Oncogenesis , Vol. 6 , Issue 9 , pp. e383 , (2017 ) (PubMed ).
Target Details for IKBKB
(hide)
Target
IKBKB
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
Alternative Name
IKBKB (IKBKB Products )
Synonyms
ikk-beta antibody, ikk2 antibody, ikkb antibody, ikkbeta antibody, IKBKB antibody, IKKB antibody, CG4201 antibody, DIK antibody, DLAK antibody, DmIKK antibody, DmIKKBeta antibody, DmIKKb antibody, DmIKKbeta antibody, DmIkkbeta antibody, Dmel\\CG4201 antibody, Dmikkb antibody, Dmikkbeta antibody, IK antibody, IKK antibody, IKK-beta antibody, IKKb antibody, IKKbeta antibody, IRD-5 antibody, IRD5 antibody, Ik antibody, Ikkb antibody, Ikkbeta antibody, Ird-5 antibody, Ird5 antibody, LRK antibody, Lak antibody, anon-89Bd antibody, dIKK antibody, dIKK-beta antibody, dIKKbeta antibody, dLak antibody, dmIKKbeta antibody, ikk antibody, ird antibody, ird5/DmIkk[beta] antibody, IKK2 antibody, NFKBIKB antibody, AIM-1 antibody, AI132552 antibody, IKK-2 antibody, IKK[b] antibody, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta L homeolog antibody, inhibitor of nuclear factor kappa B kinase subunit beta antibody, I-kappaB kinase beta antibody, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta antibody, inhibitor of kappaB kinase beta antibody, ikbkb.L antibody, IKBKB antibody, ikbkb antibody, IKKbeta antibody, Ikbkb antibody
Background
The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.,IKBKB,IKK-beta,IKK2,IKKB,IMD15,NFKBIKB,IKK beta,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,IKBKB
Molecular Weight
29 kDa/79 kDa/85 kDa/86 kDa
Gene ID
3551
UniProt
O14920
Pathways
NF-kappaB Signaling , RTK Signaling , TCR Signaling , TLR Signaling , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Production of Molecular Mediator of Immune Response , Hepatitis C , Toll-Like Receptors Cascades , BCR Signaling , Ubiquitin Proteasome Pathway , S100 Proteins
Recently viewed
(hide)