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PIM3 antibody (AA 278-326)

PIM3 Reactivity: Human ELISA, WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7169149
  • Target See all PIM3 Antibodies
    PIM3 (Pim-3 Oncogene (PIM3))
    Binding Specificity
    • 9
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 278-326
    Reactivity
    • 27
    • 12
    • 2
    Human
    Host
    • 25
    • 2
    Rabbit
    Clonality
    • 25
    • 2
    Polyclonal
    Conjugate
    • 11
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PIM3 antibody is un-conjugated
    Application
    • 15
    • 14
    • 12
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Mouse
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Serine/threonine-protein kinase pim-3 protein (278-326AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    PIM3 (Pim-3 Oncogene (PIM3))
    Alternative Name
    PIM3 (PIM3 Products)
    Synonyms
    pim1-a antibody, pim-3 antibody, BC026639 antibody, Kid1 antibody, Serine/threonine-protein kinase Pim-3 antibody, Pim-3 proto-oncogene, serine/threonine kinase S homeolog antibody, Pim-3 proto-oncogene, serine/threonine kinase antibody, pim-3 oncogene antibody, proviral integration site 3 antibody, pim3 antibody, pim3.S antibody, PIM3 antibody, Pim3 antibody
    Background

    Background: Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.

    Aliases: Kid 1 antibody, Kid1 antibody, Kinase induced by depolarization antibody, ONCOGENE PIM3 antibody, PIM 3 antibody, Pim 3 oncogene antibody, Pim-3 proto-oncogene, serine/threonine kinase antibody, PIM3 antibody, Pim3 oncogene antibody, PIM3_HUMAN antibody, Protein kinase Kid 1 antibody, Protein kinase Kid1 antibody, Serine/threonine kinase Pim 3 antibody, Serine/threonine kinase Pim3 antibody, Serine/threonine protein kinase Pim 3 antibody, Serine/threonine protein kinase Pim3 antibody, Serine/threonine-protein kinase Pim-3 antibody

    UniProt
    Q86V86
    Pathways
    Negative Regulation of Hormone Secretion
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