MICB Protein (AA 23-309) (His tag)
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- Target See all MICB Proteins
- MICB (MHC Class I Polypeptide-Related Sequence B (MICB))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-309
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MICB protein is labelled with His tag.
- Purpose
- Recombinant Human MICB Protein with C-terminal 6xHis tag
- Specificity
- MICB (Ala23-Asp309) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- MICB (MHC Class I Polypeptide-Related Sequence B (MICB))
- Alternative Name
- MICB (MICB Products)
- Synonyms
- PERB11.2 Protein, MHC class I polypeptide-related sequence B Protein, MHC class I-related protein-like Protein, MICB Protein, LOC512825 Protein
- Background
- This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
- Molecular Weight
- predicted molecular mass of 33.5 kDa after removal of the signal peptide.The apparent molecular mass of MICB-His is 35-55 kDa due to glycosylation.
- Gene ID
- 4277
- UniProt
- Q29980
- Pathways
- Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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