PKD1 antibody (AA 615-753)
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- Target See all PKD1 Antibodies
- PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))
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Binding Specificity
- AA 615-753
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PKD1 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Polycystin-1 protein (615-753AA)
- Isotype
- IgG
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anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (AA 131-230) antibody
PKD1 Reactivity: Human, Mouse ELISA, WB, IHC (p), FACS, IF (cc), IF (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) antibodyPKD1 Reactivity: Human, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (Thr310) antibodyPKD1 Reactivity: Human, Mouse, Rat ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (Thr312) antibodyPKD1 Reactivity: Human, Mouse, Rat ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (pSer205) antibodyPKD1 Reactivity: Human, Mouse, Rat ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (Thr266), (Thr312) antibodyPKD1 Reactivity: Human, Mouse, Rat ELISA, IHC, WB, IF Host: Rabbit Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (pSer910) antibodyPKD1 Reactivity: Human, Mouse, Rat ELISA, WB Host: Rabbit Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (AA 2281-2292) antibodyRecent PKD1 Reactivity: Human, Mouse, Rat, Dog, Pig ELISA Host: Goat Polyclonal unconjugated
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- Application Notes
- Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))
- Alternative Name
- PKD1 (PKD1 Products)
- Synonyms
- PBP antibody, Pc-1 antibody, TRPP1 antibody, PC1 antibody, mFLJ00285 antibody, polycystin 1, transient receptor potential channel interacting antibody, polycystin 1, transient receptor poteintial channel interacting antibody, polycystin-1 antibody, PKD1 antibody, Pkd1 antibody, LOC749291 antibody
- Background
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Background: Involved in renal tubulogenesis (PubMed:12482949). Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium (By similarity). Acts as a regulator of cilium length, together with PKD2 (By similarity). The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling (By similarity). The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling (By similarity). May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate interactions.
Aliases: Autosomal dominant polycystic kidney disease 1 protein antibody, Autosomal dominant polycystic kidney disease protein 1 antibody, nPKC-D1 antibody, nPKC-mu antibody, OTTHUMP00000208669 antibody, OTTHUMP00000208670 antibody, PBP antibody, Pc-1 antibody, PKD antibody, Pkd1 antibody, PKD1_HUMAN antibody, Polycystic Kidney Disease 1 antibody, polycystic kidney disease-associated protein antibody, Polycystin 1 Precursor antibody, Polycystin-1 antibody, Protein kinase C mu type antibody, Protein kinase D antibody, Serine/threonine-protein kinase D1 antibody, transient receptor potential cation channel, subfamily P, member 1 antibody, TRPP1 antibody
- UniProt
- P98161
- Pathways
- Myometrial Relaxation and Contraction, Maintenance of Protein Location
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