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POLH antibody (AA 408-609)

POLH Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7150247
  • Target See all POLH Antibodies
    POLH (Polymerase (DNA Directed), eta (POLH))
    Binding Specificity
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 408-609
    Reactivity
    • 42
    • 12
    • 12
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 42
    • 3
    Rabbit
    Clonality
    • 44
    • 1
    Polyclonal
    Conjugate
    • 18
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLH antibody is un-conjugated
    Application
    • 32
    • 13
    • 13
    • 11
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human DNA polymerase eta protein (408-609AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    POLH (Polymerase (DNA Directed), eta (POLH))
    Alternative Name
    POLH (POLH Products)
    Synonyms
    POLH antibody, fc50a12 antibody, wu:fc50a12 antibody, zgc:136881 antibody, zgc:152642 antibody, RAD30 antibody, RAD30A antibody, XP-V antibody, XPV antibody, polymerase (DNA directed), eta S homeolog antibody, DNA polymerase eta antibody, polymerase (DNA directed), eta antibody, putative DNA polymerase eta antibody, polymerase (DNA directed), eta (RAD 30 related) antibody, polh.S antibody, POLH antibody, polh antibody, Tb10.70.6190 antibody, LINJ_21_0690 antibody, Polh antibody, LOC100443019 antibody
    Background

    Background: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5\\\'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.

    Aliases: DNA polymerase eta antibody, FLJ16395 antibody, FLJ21978 antibody, Polh antibody, POLH_HUMAN antibody, polymerase DNA directed eta antibody, RAD30 antibody, RAD30 homolog A antibody, RAD30A antibody, Xeroderma pigmentosum variant type protein antibody, XP V antibody, XPV antibody

    UniProt
    Q9Y253
    Pathways
    DNA Damage Repair
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