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LINGO1 antibody (C-Term)
LINGO1
Reactivity: Human, Mouse
WB, IHC (p)
Host: Rabbit
Polyclonal
RB15362
unconjugated
Product Details anti-LINGO1 Antibody
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Target
See all LINGO1 Antibodies
LINGO1
(Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))
Binding Specificity
All epitopes for LINGO1 antibodies
AA 575-603, C-Term
Reactivity
All reactivities for LINGO1 antibodies
Human, Mouse
Host
All hosts for LINGO1 antibodies
Rabbit
Clonality
All clonalities for LINGO1 antibodies
Polyclonal
Conjugate
All conjugates for LINGO1 antibodies
This LINGO1 antibody is un-conjugated
Application
All applications for LINGO1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
C, Pr
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This LINGO-1(LRRN6A) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-603 amino acids from the C-terminal region of human LINGO-1(LRRN6A).
Clone
RB15362
Isotype
Ig Fraction
Alternatives
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Application Details
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Application Notes
IHC: 1:50. IHC: 1:125. WB: 1:1000-1:2000. IHC-P: 1:50~100. IHC: 1:250. IHC: 1:125
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
References for anti-LINGO1 antibody (ABIN651289)
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Towner, Jensen, Vaillant, Colman, Saunders, Giles, Wren : "Experimental validation of 5 in-silico predicted glioma biomarkers. " in: Neuro-oncology , Vol. 15 , Issue 12 , pp. 1625-34 , (2013 ) (PubMed ).
Target Details for LINGO1
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Target
LINGO1
(Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))
Alternative Name
LINGO-1 (LRRN6A) (LINGO1 Products )
Synonyms
lern1 antibody, lrrn6a antibody, unq201 antibody, DKFZp459P0736 antibody, LERN1 antibody, LRRN6A antibody, UNQ201 antibody, 4930471K13Rik antibody, AV148400 antibody, LINGO-1 antibody, Lrrn6a antibody, leucine rich repeat and Ig domain containing 1 antibody, LINGO1 antibody, lingo1 antibody, Lingo1 antibody
Background
LINGO-1 is functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. LINGO-1 is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.
Molecular Weight
69101
Gene ID
235402
NCBI Accession
NP_851419
UniProt
Q9D1T0
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