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MAPKSP1 antibody

MAPKSP1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856785
  • Target See all MAPKSP1 Antibodies
    MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
    Reactivity
    • 27
    • 18
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 30
    • 3
    Rabbit
    Clonality
    • 30
    • 3
    Polyclonal
    Conjugate
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAPKSP1 antibody is un-conjugated
    Application
    • 13
    • 13
    • 12
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Rabbit Polyclonal antibody to MP1 (MAPK scaffold protein 1)
    MP1 antibody [N1C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Full length human MP1 Recombinant protein.
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: 293T , Rat2 , Neuro2A , Raw264.7 , C2C12

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.88 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
    Alternative Name
    late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 (MAPKSP1 Products)
    Synonyms
    MAPKSP1 antibody, MAP2K1IP1 antibody, MAPBP antibody, MP1 antibody, PRO0633 antibody, Ragulator3 antibody, AW556229 antibody, Map2k1ip1 antibody, Mapbp antibody, Mapksp1 antibody, Mp1 antibody, mapksp1 antibody, zgc:110207 antibody, late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 antibody, LAMTOR3 antibody, Lamtor3 antibody, lamtor3 antibody
    Background
    This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Multiple transcript variants are expressed by this gene, but only one variant is thought to express a protein.

    Molecular Weight
    14 kDa
    Gene ID
    8649
    UniProt
    Q9UHA4
    Pathways
    PI3K-Akt Signaling
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