NCR1 Protein (mFc Tag)
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- Target See all NCR1 Proteins
- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NCR1 protein is labelled with mFc Tag.
- Sequence
- Gln22-Asn255
- Purity
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human NKp46, mFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-Nkp46 Antibody, hFc Tag with the EC50 of 18.7ng/ml determined by ELISA. See testing image for detail.
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Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-254) protein (His tag)
NCR1 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-255) protein (Fc Tag)NCR1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-254) protein (His tag)NCR1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-255) protein (His tag)NCR1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-254) protein (His tag,Biotin)NCR1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-257) (Active) protein (His tag,AVI tag,Biotin)NCR1 Origin: Cynomolgus Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-303) protein (GST tag)NCR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 17-255) protein (His tag)Crystallography grade NCR1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-258) protein (His tag)Crystallography grade NCR1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-304) protein (rho-1D4 tag)Crystallography grade NCR1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
- Alternative Name
- NKp46 (NCR1 Products)
- Synonyms
- CD335 Protein, LY94 Protein, NK-p46 Protein, NKP46 Protein, Ly94 Protein, NKp46 Protein, KILR-1 Protein, Nk-p46 Protein, Nkp46 Protein, natural cytotoxicity triggering receptor 1 Protein, NCR1 Protein, Ncr1 Protein
- Background
- CD335, Ly94, NCR1, NKp46, MAR-1, NKP46FLJ99094,NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells.
- Molecular Weight
- 52.9 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Tris-Bis PAGE result.
- Pathways
- Regulation of Leukocyte Mediated Immunity
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