Browse our TSPY-Like 2 Proteins (TSPYL2)

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TSPY-Like 2 Proteins (TSPYL2)
On are 3 TSPY-Like 2 (TSPYL2) Proteins from 2 different suppliers available. Additionally we are shipping TSPY-Like 2 Antibodies (73) and many more products for this protein. A total of 82 TSPY-Like 2 products are currently listed.
CDA1, CINAP, CTCL, DENTT, DXBwg1396e, DXHXS1008E, E130307F10Rik, HRIHFB2216, NP79, RGD1563283, SE204, TSPX, TSPYQ1
list all proteins Gene Name GeneID UniProt
TSPYL2 64591 A6NKD2
TSPYL2 52808 Q7TQI8
Rat TSPYL2 TSPYL2 302612  

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TSPY-Like 2 Proteins (TSPYL2) by Origin

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More Proteins for TSPY-Like 2 Interaction Partners

Human TSPY-Like 2 (TSPYL2) interaction partners

  1. TSPY and TSPX exert opposing effects on the transactivation functions of AR and AR-Vs important for various physiological and disease processes sensitive to male sex hormone actions, thereby not only affecting the pathogenesis of male-specific prostate cancer but also likely contributing to sex differences in the health and diseases of man.

  2. the extent of the duplicated regions in each case encompassing a minimum of three known disease genes TSPYL2, KDM5C and IQSEC2, is reported.

  3. homozygous Asp3779Asn and a hemizygous Ile262Met mutations in the LRP2 (show LRP2 Proteins) and TSPYL2 genes, respectively, in a Pakistani family with two boys affected with mild nonsyndromic intellectual disability

  4. Authors demonstrate that human coilin-interacting nuclear ATPase protein (hCINAP) is a novel negative regulator in NF-kappaB (show NFKB1 Proteins) signaling by deactivating IkappaB kinase (show CHUK Proteins) (IKK (show CHUK Proteins)) complex.

  5. TSPYL2 is an essential component of the REST/NRSF transcriptional complex for TGFbeta (show TGFB1 Proteins) signaling activation

  6. The oncogenic events leading to an ectopic activation of TSPY and/or inactivating mutation/epigenetic silencing of TSPX could collectively contribute to the sexual dimorphism(s) in HCC (show FAM126A Proteins) and related liver cancers in male-biased manners.

  7. More importantly, RPS14 (show RPS14 Proteins) was specifically modified with NEDD8 (show NEDD8 Proteins) and hCINAP inhibited RPS14 (show RPS14 Proteins) NEDDylation by recruiting NEDD8-specific protease 1 (show SENP8 Proteins)

  8. TSPX is principally expressed in Sertoli cells in the human testis.

  9. knockdown of CINAP expression results in marked reduction of histone transcription, lower levels of U small nuclear RNAs (U1, U2, U4, and U5), and a loss of cell viability

  10. Overexpression of cell division autoantigen-1 (CDA1) slowed parasite growth and induced expression of bradyzoite-specific proteins. Results showed that changes in host cell transcription can influence the molecular environment for bradyzoite development.

Mouse (Murine) TSPY-Like 2 (TSPYL2) interaction partners

  1. These findings suggest that disrupting Tspyl2 gene expression leads to behavioral and brain morphological alterations that mirror a number of neurodevelopmental psychiatric traits.

  2. Following infection with T. gondii, myotubes but not myoblasts or fibroblasts further upregulate the negative cell cycle regulator Tspyl2.

  3. We conclude that TSPYL2 contributes to cognitive variability through regulating the expression of Grin2a (show GRIN2A Proteins) and Grin2b (show GRIN2B Proteins).

  4. CDA1 deletion reduces but does not block renal TGF-beta (show TGFB1 Proteins) signaling.

  5. TSPYL2 serves a biological role in maintaining the G1 checkpoint under stress condition.

  6. DENTT may play a role in development of the endocrine tissues, nervous system, lung, oocytes, and thecal cells, and testis [DENTT]

  7. DENTT may play multiple roles in modulating transcriptional responses suggesting new roles for the TTSN superfamily during embryogenesis and differentiation.

  8. Mice treated with hypertonic saline expressed higher CINAP protein levels in the PVN, supporting a role of CINAP in neural response in vivo.

TSPY-Like 2 (TSPYL2) Protein Profile

Protein Summary

This gene encodes a member of the testis-specific protein Y-encoded, TSPY-like/SET/nucleosome assembly protein-1 superfamily. The encoded protein is localized to the nucleolus where it functions in chromatin remodeling and as an inhibitor of cell-cycle progression. This protein may play a role in the suppression of tumor growth.

Alternative names and synonyms associated with TSPY-Like 2 (TSPYL2)

  • TSPY-like 2 (tspyl2)
  • TSPY-like 2 (TSPYL2)
  • TSPY-like 2 (Exig_1158)
  • testis specific protein, Y-linked 2 (TSPY2)
  • TSPY-like 2 (Tspyl2)
  • CDA1 protein
  • CINAP protein
  • CTCL protein
  • DENTT protein
  • DXBwg1396e protein
  • DXHXS1008E protein
  • E130307F10Rik protein
  • HRIHFB2216 protein
  • NP79 protein
  • RGD1563283 protein
  • SE204 protein
  • TSPX protein
  • TSPYQ1 protein

Protein level used designations for TSPY-Like 2 Proteins (TSPYL2)

TSPY-like 2 , testis-specific Y-encoded protein 2 , testis-specific Y-encoded protein Q1 , CASK-interacting nucleosome assembly protein , CTCL tumor antigen se20-4 , CTCL-associated antigen se20-4 , TSPY-like protein 2 , cell division autoantigen 1 , cutaneous T-cell lymphoma-associated antigen se20-4 , cutaneous T-cell lymphoma-associated tumor antigen se20-4 , differentially expressed nucleolar TGF-beta1 target , differentially-expressed nucleolar TGF-beta1 target protein , nuclear protein of 79 kDa , testis-specific Y-encoded-like protein 2 , testis-specific protein Y encoded-like 2 , CASK interacting nucleosome assembly protein , cell division autoantigen 1 nucleolar protein , nucleolar TGF-beta1 target protein

549565 Xenopus (Silurana) tropicalis
698766 Macaca mulatta
744228 Pan troglodytes
6173128 Exiguobacterium sibiricum 255-15
100158427 Xenopus laevis
100341465 Oryctolagus cuniculus
64591 Homo sapiens
64061 Homo sapiens
52808 Mus musculus
491893 Canis lupus familiaris
617179 Bos taurus
302612 Rattus norvegicus
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