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Human Monoclonal NR4A3 Primary Antibody for ELISA, WB - ABIN969434
Tsai, Chow, Chen, Huang, Hong, Jan, Kuo, Tsao, Chen, Cheng: Cef1p is a component of the Prp19p-associated complex and essential for pre-mRNA splicing. in The Journal of biological chemistry 1999
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Human Polyclonal NR4A3 Primary Antibody for IHC (p), ELISA - ABIN4369826
Nore, Mattsson, Antonsson, Bäckesjö, Westlund, Lennartsson, Hansson, Löw, Rönnstrand, Smith: Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases. in Biochimica et biophysica acta 2003
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Human Monoclonal NR4A3 Primary Antibody for IF, ELISA - ABIN521726
Rodríguez-Calvo, Guadall, Calvayrac, Navarro, Alonso, Ferrán, de Diego, Muniesa, Osada, Rodríguez, Martínez-González: Over-expression of neuron-derived orphan receptor-1 (NOR-1) exacerbates neointimal hyperplasia after vascular injury. in Human molecular genetics 2013
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Bat Polyclonal NR4A3 Primary Antibody for IHC (p) - ABIN270817
Nomiyama, Nakamachi, Gizard, Heywood, Jones, Ohkura, Kawamori, Conneely, Bruemmer: The NR4A orphan nuclear receptor NOR1 is induced by platelet-derived growth factor and mediates vascular smooth muscle cell proliferation. in The Journal of biological chemistry 2006
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Human Polyclonal NR4A3 Primary Antibody for WB - ABIN4235536
Cramer, Shao, Wang, Yuan: miR-190 is upregulated in Epstein-Barr Virus type I latency and modulates cellular mRNAs involved in cell survival and viral reactivation. in Virology 2014
Human Monoclonal NR4A3 Primary Antibody for IF, WB - ABIN393947
Medunjanin, Daniel, Weinert, Dutzmann, Burgbacher, Brecht, Bruemmer, Kähne, Naumann, Sedding, Zuschratter, Braun-Dullaeus: DNA-dependent protein kinase (DNA-PK) permits vascular smooth muscle cell proliferation through phosphorylation of the orphan nuclear receptor NOR1. in Cardiovascular research 2015
Human Monoclonal NR4A3 Primary Antibody for ELISA, WB - ABIN967165
van Dijk, van Den Akker, Amelsvoort, Mano, Löwenberg, von Lindern: Stem cell factor induces phosphatidylinositol 3'-kinase-dependent Lyn/Tec/Dok-1 complex formation in hematopoietic cells. in Blood 2000
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VTN (show VTN Antibodies) levels were increased in cell supernatants from vascular smooth muscle cells that overexpress NOR-1
NR4A2 (show NR4A2 Antibodies) and NR4A3 are components of a downstream transcriptional response to PKA activation in the neutrophil, and that they positively regulate neutrophil survival and homeostasis.
NOR1 suppresses cancer stem-like cell properties in nasopharyngeal carcinoma cells by inhibiting the AKT (show AKT1 Antibodies)-GSK-3beta (show GSK3b Antibodies)-Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies)-ALDH1A1 (show ALDH1A1 Antibodies) signaling circuit.
Transcript analysis of four different aggressive lymphoma cell lines overexpressing either NR4A3 or NR4A1 (show NR4A1 Antibodies) revealed that apoptosis was driven similarly by induction of BAK (show BAK1 Antibodies), Puma (show BBC3 Antibodies), BIK (show BIK Antibodies), BIM (show BCL2L11 Antibodies), BID (show BID Antibodies), and Trail. Overall, our results showed that NR4A3 possesses robust tumor suppressor functions of similar impact to NR4A1 (show NR4A1 Antibodies) in aggressive lymphomas
Study found a marked down-regulated gene expression of the NR4A subfamily (NR4A1 (show NR4A1 Antibodies), NR4A2 (show NR4A2 Antibodies), and NR4A3) obtained from Parkinson's disease patients, but only a NR4A1 (show NR4A1 Antibodies) decrease in Alzheimer's disease patients compared to healthy controls. This study reports that the entire NR4A subfamily and not only NR4A2 (show NR4A2 Antibodies) could be systemically involved in Parkinson's disease.
the role of intragenic DNA hypermethylation in reducing the expression of NR4A3 in AML (show RUNX1 Antibodies)
Overexpression of NR4A3 in adipocytes produces a complex phenotype characterized by impaired glucose metabolism and low serum catecholamines due to enhanced degradation by adipose tissue.
NOR1 promotes the progression of hepatocellular carcinoma cells by activating Notch (show NOTCH1 Antibodies) pathway.
using RNA interference, the identified compounds corroborate the role of Tec kinase in unconventional secretion of FGF2 (show FGF2 Antibodies).
accumulation of NR4A3 is specific to alpha-synucleinopathy.
these data indicate that in mature B cells, Tec and Btk may compete for activation of the Akt signaling pathway, whereby the activating capacity of Btk is limited by the presence of Tec kinase.
NR4A3 plays an important role in the regulation of CD103 (show ITGAE Antibodies)+ mDCs by regulating CCR7 (show CCR7 Antibodies)-dependent cell migration.
PLSCR1 (show PLSCR1 Antibodies) aggravates anaphylactic reactions by increasing Fc epsion RI-dependent mast cell degranulation.
Genetic knockdown of PLSCR1 (show PLSCR1 Antibodies) activity reduces intracellular calcium dysregulation, prevents phosphatidylserine externalization, and enables months-long protection of vector-transduced, transgene-expressing cells from microglial phagocytosis.
Study shows that NOR-1 can transduce survival signals in neuronal cells responsible for hypoxiainduced apoptotic insults through activation of a CREB (show CREB1 Antibodies)/cIAP2 (show BIRC3 Antibodies)-dependent mechanism
Promoting Liver X receptor-alpha (show NR1H3 Antibodies) expression inhibits lipopolysaccharide induced inflammation in Kupffer cells through elevating NOR-1 expression.
Identified Nur77 (show NR4A1 Antibodies)/Nor1 as novel regulators of thrombomodulin (show THBD Antibodies) expression and function in vascular endothelial cells.
Nr4a3 factor plays crucial role regulatory T cells, mediating the two defining characteristics of regulatory T cells: stability of cell lineage and immunosuppressive functions.
Tec enhances c-Maf (show MAF Antibodies)-dependent IL-4 (show IL4 Antibodies) promoter activity. This effect of Tec is counteracted by Ptpn22 (show PTPN22 Antibodies), which physically interacts with and facilitates tyrosine dephosphorylation of c-Maf (show MAF Antibodies) thereby attenuating its transcriptional activity.
Phospholipid scramblase 1 regulates phosphatidylserine exposure in response to oxygen stress, leading to beta2-glycoprotein I and IgM binding and lipid-mediated, inflammatory responses.
The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
nuclear receptor subfamily 4, group A, member 3
, chondrosarcoma, extraskeletal myxoid, fused to EWS
, mitogen-induced nuclear orphan receptor
, neuron-derived orphan receptor 1
, nuclear hormone receptor NOR-1
, nuclear receptor subfamily 4 group A member 3
, translocated in extraskeletal chondrosarcoma
, neural orphan nuclear receptor NOR1
, neural orphan receptor 1
, orphan nuclear receptor TEC
, neuron-derived orphan receptor 1/2
, nuclear hormone receptor NOR-1/NOR-2
, PL scramblase 1
, ca(2+)-dependent phospholipid scramblase 1
, transplantability-associated protein 1
, tyrosine-protein kinase Tec
, cytoplasmic tyrosine kinase, Dscr28C related