Browse our anti-TRIB3 (TRIB3) Antibodies

Full name:
anti-Tribbles Homolog 3 (Drosophila) Antibodies (TRIB3)
On are 138 Tribbles Homolog 3 (Drosophila) (TRIB3) Antibodies from 16 different suppliers available. Additionally we are shipping TRIB3 Kits (9) and TRIB3 Proteins (8) and many more products for this protein. A total of 168 TRIB3 products are currently listed.
C20orf97, Ifld2, Nipk, SINK, SKIP3, TRB-3, Trb3, TRIB3, zgc:76966
list all antibodies Gene Name GeneID UniProt
TRIB3 57761 Q96RU7
TRIB3 228775 Q8K4K2
TRIB3 246273 Q9WTQ6

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Top referenced anti-TRIB3 Antibodies

  1. Human Polyclonal TRIB3 Primary Antibody for EIA, IHC (p) - ABIN360673 : Du, Herzig, Kulkarni, Montminy: TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. in Science (New York, N.Y.) 2003 (PubMed)
    Show all 3 references for 360673

  2. Human Polyclonal TRIB3 Primary Antibody for ICC, IF - ABIN252371 : Loewen, Chen, Dudley, Sarthy, Mathura: Genomic response of hypoxic Müller cells involves the very low density lipoprotein receptor as part of an angiogenic network. in Experimental eye research 2009 (PubMed)
    Show all 3 references for 252371

  3. Human Polyclonal TRIB3 Primary Antibody for EIA, WB - ABIN360674 : Wu, Xu, Zhai, Shu: SINK is a p65-interacting negative regulator of NF-kappaB-dependent transcription. in The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for 360674

  4. Mouse (Murine) Polyclonal TRIB3 Primary Antibody for WB - ABIN3023241 : Wennemers, Bussink, Grebenchtchikov, Sweep, Span: TRIB3 protein denotes a good prognosis in breast cancer patients and is associated with hypoxia sensitivity. in Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011 (PubMed)

More Antibodies against TRIB3 Interaction Partners

Zebrafish Tribbles Homolog 3 (Drosophila) (TRIB3) interaction partners

  1. study proposes that Trb3 governs left-right (LR) axis patterning as a component of TGF-signaling in embryonic development

Human Tribbles Homolog 3 (Drosophila) (TRIB3) interaction partners

  1. TRIB3 promotes acute promyelocytic leukemia (show PML Antibodies) progression through stabilization of the oncoprotein PML (show PML Antibodies)-RARalpha (show RARA Antibodies) and inhibition of p53 (show TP53 Antibodies)-mediated senescence.

  2. Downregulation of TRIB3 is associated with lung cancer.

  3. This study aims to investigate whether the Tribbles 3 Q84R polymorphism has profound effects on serum semaphorin 3E (show SEMA3E Antibodies) and what effect semaphorin 3E (show SEMA3E Antibodies) exerts on carotid atherosclerosis.

  4. overexpression of TRIB3 is associated with tumor angiogenesis and a poor prognosis in patients with gastric cancer (GC) . Our findings indicate that TRIB3 is a promising target for antiangiogenic therapy in GC.

  5. Our findings suggest that good glucose and blood pressure control exhibited greater benefits on vascular outcomes in patients with TRIB3 (rs2295490) G allele.

  6. In this exploratory analysis, IRS1 (show IRS1 Antibodies), ENNP1 and TRIB3, known to be associated with type 2 diabetes and harboring genes playing a prominent role in mediating insulin (show INS Antibodies) signaling, may modulate a number of cardiometabolic phenotypes in patients of Italian ancestry with newly-diagnosed type 2 diabetes.

  7. TRIB3 acts as a crucial 'stress adjusting switch' that links homeostasis, metabolic disease and cancer; and is being actively investigated as a disease biomarker and therapeutic target

  8. TRB3 (show TAS2R13 Antibodies) is upregulated in macrophages upon treatment with ox-LDL. TRB3 (show TAS2R13 Antibodies) promotes lipid accumulation and suppresses cytokine expression, suggesting inflammation and foam cell formation can be reciprocally regulated.

  9. Studies suggest that pseudo-kinase family of tribbles (show TRIB1 Antibodies) (TRIB) proteins TRIB1 (show TRIB1 Antibodies), TRIB2 (show TRIB2 Antibodies) and TRIB3 play roles in pathogenesis of rheumatoid arthritis (RA) and osteoarthritis.

  10. Studies suggest that pseudo-kinase family of tribbles (show TRIB1 Antibodies) (TRIB) proteins TRIB1 (show TRIB1 Antibodies), TRIB2 (show TRIB2 Antibodies) and TRIB3 were involved in the pathogenesis of inflammation.

Mouse (Murine) Tribbles Homolog 3 (Drosophila) (TRIB3) interaction partners

  1. Chac1 (show CHAC1 Antibodies) expression is detrimental to arsenite-treated cell survival and TRIB3 is critical for restraining the pro-death potential of Chac1 (show CHAC1 Antibodies) during arsenite stress.

  2. Under physiological conditions, muscle TRIB3 also influences energy expenditure and substrate metabolism, indicating that the decrease and increase in muscle TRIB3 under fasting and nutrient excess, respectively, are critical for metabolic homeostasis.

  3. In a knockout mouse model, Trib3 disruption modestly increased steady-state erythrocyte numbers and decreased mean corpuscular volume.

  4. Palmitate increased TRB3 expression, activated IRE1alpha (show ERN1 Antibodies) signaling, and reduced the insulin (show INS Antibodies)-dependent Akt (show AKT1 Antibodies) phosphorylation. Knocking down TRB3 or IRE1alpha (show ERN1 Antibodies) did not prevent the inhibitory effect of palmitate on Akt (show AKT1 Antibodies) phosphorylation. Results support the idea that ER stress is not responsible for lipid-induced IR in C2C12 myotubes.

  5. These data demonstrate that TRB3 inhibits insulin (show INS Antibodies) signaling in BAT (show BAAT Antibodies), resulting in impaired differentiation and function.

  6. TRB3 is a novel profibrotic mediator in SSc (show CYP11A1 Antibodies). TGF-beta (show TGFB1 Antibodies) induces TRB3, which in turn activates canonical TGF-beta (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies) signaling and stimulates the release of collagen, creating a positive feedback loop that may contribute to aberrant TGF-beta (show TGFB1 Antibodies) signalling in SSc (show CYP11A1 Antibodies).

  7. study presents the finding that activation of the NF-kappaB (show NFKB1 Antibodies) pathway by Porphyromonas endodontalis LPS (show TLR4 Antibodies) is important for Wnt5a (show WNT5A Antibodies) expression in osteoblasts, and that TRIB3 may modulate the sustained expression of Wnt5a (show WNT5A Antibodies) in osteoblasts stimulated by P. endodontalis

  8. TRIB1 (show TRIB1 Antibodies) and TRIB3 are more strongly expressed than TRIB2 (show TRIB2 Antibodies) in cumulus cells (CC) surrounding oocytes from preovulatory follicles than in CC of immature ones.

  9. Trib3 interferes with the Parkinson's disease-associated prosurvival protein Parkin (show PARK2 Antibodies) to mediate death

  10. These observations support the notion that loss of TRIB3 is associated with a more aggressive phenotype in various types of tumors by enhancing the activity of the mTORC2 (show CRTC2 Antibodies)/AKT (show AKT1 Antibodies)/FOXO (show FOXO3 Antibodies) axis.

Pig (Porcine) Tribbles Homolog 3 (Drosophila) (TRIB3) interaction partners

  1. This work aimed to study the porcine tribbles homolog 3 (TRIB3) gene and to evaluate its association with meat quality and carcass traits in pigs.

TRIB3 Antigen Profile

Antigen Summary

The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1.

Alternative names and synonyms associated with TRIB3

  • tribbles homolog 3 (Drosophila) (trib3) antibody
  • tribbles homolog 3 (Drosophila) (TRIB3) antibody
  • tribbles 3 (TRIB3) antibody
  • tribbles homolog 3 (Drosophila) (Trib3) antibody
  • C20orf97 antibody
  • Ifld2 antibody
  • Nipk antibody
  • SINK antibody
  • SKIP3 antibody
  • TRB-3 antibody
  • Trb3 antibody
  • TRIB3 antibody
  • zgc:76966 antibody

Protein level used designations for TRIB3

tribbles homolog 3 , tribbles homolog 3 (Drosophila) , tribbles homolog 3-like , TRB-3 , neuronal cell death inducible putative kinase , neuronal cell death-inducible putative kinase , p65-interacting inhibitor of NF-kappa-B , p65-interacting inhibitor of NF-kappaB , induced in fatty liver dystrophy 2 , Neuronal cell death Inducible Putative Kinase , kinase , tribbles 3

405805 Danio rerio
714636 Macaca mulatta
100439080 Pongo abelii
100603917 Nomascus leucogenys
745623 Pan troglodytes
57761 Homo sapiens
485819 Canis lupus familiaris
228775 Mus musculus
246273 Rattus norvegicus
538465 Bos taurus
100518810 Sus scrofa
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