Browse our anti-EXT1 (EXT1) Antibodies

Full name:
anti-Exostosin 1 Antibodies (EXT1)
On www.antibodies-online.com are 57 Exostosin 1 (EXT1) Antibodies from 17 different suppliers available. Additionally we are shipping EXT1 Kits (16) and EXT1 Proteins (8) and many more products for this protein. A total of 89 EXT1 products are currently listed.
Synonyms:
AA409028, EXT, LGCR, LGS, TRPS2, TTV, xext1
list all antibodies Gene Name GeneID UniProt
EXT1 14042 P97464
EXT1 2131 Q16394
EXT1 299907  

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Most Popular Reactivities for anti-EXT1 (EXT1) Antibodies

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anti-Mouse (Murine) EXT1 Antibodies:

anti-Human EXT1 Antibodies:

anti-Rat (Rattus) EXT1 Antibodies:

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Top referenced anti-EXT1 Antibodies

  1. Human Polyclonal EXT1 Primary Antibody for EIA, WB - ABIN952144 : Zuntini, Pedrini, Parra, Sgariglia, Gentile, Pandolfi, Alberghini, Sangiorgi: Genetic models of osteochondroma onset and neoplastic progression: evidence for mechanisms alternative to EXT genes inactivation. in Oncogene 2010 (PubMed)
    Show all 3 references for 952144

  2. Human Polyclonal EXT1 Primary Antibody for IF, WB - ABIN515425 : Tian, Yan, Wen, Li, Li, Cai, Li, Du, Chen: A splice mutation and mRNA decay of EXT2 provoke hereditary multiple exostoses. in PLoS ONE 2014 (PubMed)

  3. Human Polyclonal EXT1 Primary Antibody for IHC, IHC (p) - ABIN4309793 : Coulson-Thomas, Gesteira, Esko, Kao: Heparan sulfate regulates hair follicle and sebaceous gland morphogenesis and homeostasis. in The Journal of biological chemistry 2014 (PubMed)

More Antibodies against EXT1 Interaction Partners

Zebrafish Exostosin 1 (EXT1) interaction partners

  1. the three zebrafish ext1 genes encode proteoglycan (show Vcan Antibodies) modifying enzymes and have distinct relationships to somitic Sonic hedgehog (show SHH Antibodies) signaling

Mouse (Murine) Exostosin 1 (EXT1) interaction partners

  1. reactivating SHH (show SHH Antibodies) signaling in mutant lungs rescued the tip dilation phenotype and attenuated FGF signaling. Importantly, the reduced SHH (show SHH Antibodies) signaling activity did not appear to be caused by decreased Shh (show SHH Antibodies) expression or protein stability; instead, biologically active form of SHH (show SHH Antibodies) proteins were reduced in both the Ext1 mutant epithelium and surrounding wild type mesenchymal cells.

  2. Normal heparin sulfate levels and Ext1 activity in the stromal microenvironment and hematopoietic stem cells are required for the transplant engraftment following non-myeloablative conditioning.

  3. Heterozygous loss of function of EXT1 and EXT2 results in a decreased arteriolar endothelial glycocalyx but improved flow mediated vasodilation.

  4. Ext genes and heparan sulfate are needed to establish and maintain perichondrium's phenotype and border function.

  5. Levels of Ext1 and HPSE (show HPSE Antibodies) influence the motility of FBJ osteosarcoma cells.

  6. stromal Ext1-levels modulate tumor cell proliferation and affect the interstitial fluid pressure in a 3-D spheroid model.

  7. The study indicates that formation of stereotypic exostoses requires a significant, but not complete, loss of Ext expression.

  8. local Ext1 expression and heparan sulfate production are needed to maintain the phenotype and function of joint-forming cells.

  9. Ext1 has a role in regulation of bone morphogenic protein signaling and skeletal defects

  10. inactivation of Ext1 in a small fraction of chondrocytes is sufficient for the development of osteochondromas and other skeletal defects associated with multiple hereditary exostoses

Human Exostosin 1 (EXT1) interaction partners

  1. EXT1, a gene not previously linked to acute lymphoblastic leukemia via mutations, is a common interactor of NOTCH1 (show NOTCH1 Antibodies) and FBXW7 (show FBXW7 Antibodies) regulating the NOTCH (show NOTCH1 Antibodies) pathway in an FBXW7 (show FBXW7 Antibodies)-dependend manner.

  2. A novel heterozygous point mutation (c.1164+1G to A) at the 5'splice sites of intron 3 of the EXT1 gene is associated with multiple osteochondroma.

  3. EXT1 is up regulated in patients after chronic rhinosinusitis, developing osteitis.

  4. We report the discovery of a non-sense mutation in EXT2 (show EXT2 Antibodies) in an 11 (show DCAF7 Antibodies)-y-old boy diagnosed with multiple osteochondroma.

  5. We found that the prevalence of EXT1 mutations was greater than that of EXT2 mutations in Japanese multiple osteochondromas families.

  6. Ext1 heterozygosity causes a modest effect on postprandial lipid clearance in humans

  7. EXT1 mutation is associated with multiple osteochondromatosis.

  8. Heterozygous loss of function of EXT1 and EXT2 results in a decreased arteriolar endothelial glycocalyx but improved flow mediated vasodilation.

  9. there is a putative genetic connection between TCF7L2 and EXT in the context of Hereditary Multiple Exostoses

  10. loss of function of EXT1 subjects with hereditary multiple exostoses affects pancreatic insulin (show INS Antibodies) secretion capacity and development.

EXT1 Antigen Profile

Antigen Summary

This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses.

Alternative names and synonyms associated with EXT1

  • exostoses (multiple) 1b (ext1b) antibody
  • exostoses (multiple) 1 (Ext1) antibody
  • exostoses (multiple)-like 1 (EXTL1) antibody
  • exostosin 1 (EXT1) antibody
  • exostosin glycosyltransferase 1 (EXT1) antibody
  • exostosin glycosyltransferase 1 (Ext1) antibody
  • exostosin glycosyltransferase 1 (ext1) antibody
  • exostosin-1-like (LOC100537794) antibody
  • AA409028 antibody
  • EXT antibody
  • LGCR antibody
  • LGS antibody
  • TRPS2 antibody
  • TTV antibody
  • xext1 antibody

Protein level used designations for anti-Exostosin 1 (EXT1) Antibodies

exostosin-1b , glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase 1b , multiple exostoses protein 1 homolog b , exostosin-1 , glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase , multiple exostoses protein 1 homolog , Heparan sulfate copolymerase , Multiple exostoses protein 1 homolog , exostosin 1 , exostoses-like 1 , Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase , exostoses (multiple) 1 , Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N- acetylglucosaminyltransferase , Langer-Giedion syndrome chromosome region , N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase , multiple exostoses protein 1 , putative tumor suppressor protein EXT1

GENE ID SPECIES
497280 Danio rerio
14042 Mus musculus
100689334 Cricetulus griseus
100347418 Oryctolagus cuniculus
538602 Bos taurus
2131 Homo sapiens
299907 Rattus norvegicus
399115 Xenopus laevis
100537794 Danio rerio
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