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Browse our anti-EXT1 (EXT1) Antibodies

Full name:
anti-Exostosin 1 Antibodies (EXT1)
On are 56 Exostosin 1 (EXT1) Antibodies from 17 different suppliers available. Additionally we are shipping EXT1 Kits (15) and EXT1 Proteins (8) and many more products for this protein. A total of 87 EXT1 products are currently listed.
AA409028, EXT, LGCR, LGS, TRPS2, TTV, xext1
list all antibodies Gene Name GeneID UniProt
EXT1 14042 P97464
EXT1 2131 Q16394
EXT1 299907  

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Most Popular Reactivities for anti-EXT1 (EXT1) Antibodies

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anti-Mouse (Murine) EXT1 Antibodies:

anti-Human EXT1 Antibodies:

anti-Rat (Rattus) EXT1 Antibodies:

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Top referenced anti-EXT1 Antibodies

  1. Human Polyclonal EXT1 Primary Antibody for EIA, WB - ABIN952144 : Zuntini, Pedrini, Parra, Sgariglia, Gentile, Pandolfi, Alberghini, Sangiorgi: Genetic models of osteochondroma onset and neoplastic progression: evidence for mechanisms alternative to EXT genes inactivation. in Oncogene 2010 (PubMed)
    Show all 3 references for ABIN952144

  2. Human Polyclonal EXT1 Primary Antibody for IHC, IHC (p) - ABIN4309793 : Coulson-Thomas, Gesteira, Esko, Kao: Heparan sulfate regulates hair follicle and sebaceous gland morphogenesis and homeostasis. in The Journal of biological chemistry 2014 (PubMed)

  3. Human Polyclonal EXT1 Primary Antibody for IF, WB - ABIN515425 : Tian, Yan, Wen, Li, Li, Cai, Li, Du, Chen: A splice mutation and mRNA decay of EXT2 provoke hereditary multiple exostoses. in PLoS ONE 2014 (PubMed)

  4. Human Polyclonal EXT1 Primary Antibody for WB - ABIN2161060 : de Andrea, Reijnders, Kroon, de Jong, Hogendoorn, Szuhai, Bovée: Secondary peripheral chondrosarcoma evolving from osteochondroma as a result of outgrowth of cells with functional EXT. in Oncogene 2012 (PubMed)

More Antibodies against EXT1 Interaction Partners

Zebrafish Exostosin 1 (EXT1) interaction partners

  1. the three zebrafish ext1 genes encode proteoglycan (show Vcan Antibodies) modifying enzymes and have distinct relationships to somitic Sonic hedgehog (show SHH Antibodies) signaling

Mouse (Murine) Exostosin 1 (EXT1) interaction partners

  1. Normal heparin sulfate levels and Ext1 activity in the stromal microenvironment and hematopoietic stem cells are required for the transplant engraftment following non-myeloablative conditioning.

  2. Heterozygous loss of function of EXT1 and EXT2 results in a decreased arteriolar endothelial glycocalyx but improved flow mediated vasodilation.

  3. Ext genes and heparan sulfate are needed to establish and maintain perichondrium's phenotype and border function.

  4. Levels of Ext1 and HPSE (show HPSE Antibodies) influence the motility of FBJ osteosarcoma cells.

  5. stromal Ext1-levels modulate tumor cell proliferation and affect the interstitial fluid pressure in a 3-D spheroid model.

  6. The study indicates that formation of stereotypic exostoses requires a significant, but not complete, loss of Ext expression.

  7. local Ext1 expression and heparan sulfate production are needed to maintain the phenotype and function of joint-forming cells.

  8. Ext1 has a role in regulation of bone morphogenic protein signaling and skeletal defects

  9. inactivation of Ext1 in a small fraction of chondrocytes is sufficient for the development of osteochondromas and other skeletal defects associated with multiple hereditary exostoses

  10. for a model of multiple osteochondromas, we created the chimeric tissue genotype of somatic loss of heterozygosity, by conditionally inactivating Ext1 in chondrocytes

Human Exostosin 1 (EXT1) interaction partners

  1. We report the discovery of a non-sense mutation in EXT2 (show EXT2 Antibodies) in an 11 (show DCAF7 Antibodies)-y-old boy diagnosed with multiple osteochondroma.

  2. We found that the prevalence of EXT1 mutations was greater than that of EXT2 mutations in Japanese multiple osteochondromas families.

  3. Ext1 heterozygosity causes a modest effect on postprandial lipid clearance in humans

  4. EXT1 mutation is associated with multiple osteochondromatosis.

  5. Heterozygous loss of function of EXT1 and EXT2 results in a decreased arteriolar endothelial glycocalyx but improved flow mediated vasodilation.

  6. there is a putative genetic connection between TCF7L2 and EXT in the context of Hereditary Multiple Exostoses

  7. loss of function of EXT1 subjects with hereditary multiple exostoses affects pancreatic insulin (show INS Antibodies) secretion capacity and development.

  8. Results provide a new frameshift mutation in EXT1, further emphasizing the dysfunction of the EXT gene family as a cause of hereditary multiple exostosis.

  9. exostosin 1 (EXT1), which is involved in biosynthesis of heparan sulfate, plays a role in filovirus entry

  10. EXT1 and EXT2 heterozygous mutations in 18 (54.6 %) and ten (30.3 %) probands respectively, which represents a total of 28 (84.9 %) index cases.

EXT1 Antigen Profile

Antigen Summary

This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses.

Alternative names and synonyms associated with EXT1

  • exostoses (multiple) 1b (ext1b) antibody
  • exostoses (multiple) 1 (Ext1) antibody
  • exostoses (multiple)-like 1 (EXTL1) antibody
  • exostosin 1 (EXT1) antibody
  • exostosin glycosyltransferase 1 (EXT1) antibody
  • exostosin glycosyltransferase 1 (Ext1) antibody
  • exostosin glycosyltransferase 1 (ext1) antibody
  • exostosin-1-like (LOC100537794) antibody
  • AA409028 antibody
  • EXT antibody
  • LGCR antibody
  • LGS antibody
  • TRPS2 antibody
  • TTV antibody
  • xext1 antibody

Protein level used designations for anti-Exostosin 1 (EXT1) Antibodies

exostosin-1b , glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase 1b , multiple exostoses protein 1 homolog b , exostosin-1 , glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase , multiple exostoses protein 1 homolog , Heparan sulfate copolymerase , Multiple exostoses protein 1 homolog , exostosin 1 , exostoses-like 1 , Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase , exostoses (multiple) 1 , Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N- acetylglucosaminyltransferase , Langer-Giedion syndrome chromosome region , N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase , multiple exostoses protein 1 , putative tumor suppressor protein EXT1

497280 Danio rerio
14042 Mus musculus
100689334 Cricetulus griseus
100347418 Oryctolagus cuniculus
538602 Bos taurus
2131 Homo sapiens
299907 Rattus norvegicus
399115 Xenopus laevis
100537794 Danio rerio
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