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anti-Human HYAL3 Antibodies:
anti-Mouse (Murine) HYAL3 Antibodies:
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Human Monoclonal HYAL3 Primary Antibody for ELISA - ABIN563606
Monzón, Manzanares, Schmid, Casalino-Matsuda, Forteza: Hyaluronidase expression and activity is regulated by pro-inflammatory cytokines in human airway epithelial cells. in American journal of respiratory cell and molecular biology 2008
the relative expression of hyalurosome (CD44 (show CD44 Antibodies), HAS3 (show HAS3 Antibodies), HB-EGF (show HBEGF Antibodies)) genes was found to be reduced in patients prior to topical treatment and to be notably increased following treatment.
mutations of the HYAL3 (show SPAM1 Antibodies) gene are rare in Chinese lung squamous cell carcinoma patients and might contribute to lymph node metastasis
polymorphisms in HYAL3 (show SPAM1 Antibodies) are potentially involved in glaucomatous neurodegeneration.
Nodular basal cell carcinoma is associated with increased levels of hyaluronic acid concomitant with upregulation of gene expression of HAS3 (show HAS3 Antibodies), HYAL3 (show SPAM1 Antibodies) and RHAMM (show HMMR Antibodies), when compared with normal adjacent skin.
Overexpression of HYAL3 (show SPAM1 Antibodies) is associated with colorectal cancer.
Hyal3 (show SPAM1 Antibodies) null sperm showed delayed cumulus penetration and reduced acrosomal exocytosis.
Characterization of the murine hyaluronidase (show HAase Antibodies) gene region reveals complex organization and cotranscription of Hyal1 (show HYAL1 Antibodies) with downstream genes, Fus2 (show NAT6 Antibodies) and Hyal3 (show SPAM1 Antibodies).
Alternative mRNA splicing controls cellular expression of enzymatically active hyaluronidase (show HAase Antibodies).
Down-regulation of HYAL3 (show SPAM1 Antibodies) is associated with small cell lung cancer and glioma
Data show that Hyal-1 (show HYAL1 Antibodies), but not Hyal-3,is an ovarian regulator factor for follicle development, and show an interrelationship between this enzyme and the follistatin (show FST Antibodies)/activin (show Actbeta Antibodies)/Smad3 (show SMAD3 Antibodies) pathway.
Hyal3 null sperm showed delayed cumulus penetration and reduced acrosomal exocytosis.
Characterization of the murine hyaluronidase (show HAase Antibodies) gene region reveals complex organization and cotranscription of Hyal1 (show HYAL1 Antibodies) with downstream genes, Fus2 (show NAT6 Antibodies) and Hyal3.
Hyal3 may contribute to hyaluronan metabolism by augmenting the activity of Hyal1 (show HYAL1 Antibodies).
Hyaluronidase (show HAase Antibodies) induces ovarian granulosa cell apoptosis and is involved in follicular atresia.
HYAL3 does not play a major role in constitutive hyaluronan degradation
the porcine hyaluronidase (show HAase Antibodies) cluster consisting of genes HYAL1 (show HYAL1 Antibodies), HYAL2 (show HYAL2 Antibodies) and HYAL3 was characterized
This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon.
, hyaluronoglucosaminidase 1
, hyaluronoglucosaminidase 3
, hyaluronidase 3
, lung carcinoma protein 3